检索结果-南通市图书馆

A mouse model of weight-drop closed head injury:emphasis on cognitive and neurological deficiency

neural regeneration Research 2016年第4期11卷 630-635页

作者： Igor Khalin Nor Laili Azua Jamari Nadiawati Bt Abdul Razak Zubaidah Bt Hasain Mohd Asri bin Mohd Nor Mohd Hakimi bin Ahmad Zainudin Ainsah Bt Omar Renad Alyautdin Faculty of Medicine and Defence Health National Defence University of MalaysiaKem Sungai BesiKuala LumpurMalaysia chemistry Department Centre for Defence Foundation StudiesNational Defence University of MalaysiaKem Sungai BesiKuala LumpurMalaysia Department of civil Engineering Faculty of EngineeringNational Defence University of MalaysiaKem Sungai BesiKuala LumpurMalaysia centre for Research and Innovation Management National Defence University of MalaysiaKem Sungai BesiKuala LumpurMalaysia Scientific centre for Expertise of Medical Application Products Petrovsky BlvdMoscowRussia

traumatic brain injury（TBI） is a leading cause of death and disability in individuals *** a clinically relevant TBI model in small-sized animals remains fairly *** good screening of potential therapeutics,which are effective in the treatment of TBI,animal models of TBI should be established and *** this study,we established mouse models of closed head injury using the Shohami weight-drop method with some modifications concerning cognitive deficiency assessment and provided a detailed description of the severe TBI animal *** found that 250 g falling weight from 2 cm height produced severe closed head injury in c57bl/6 male *** disorders in mice with severe closed head injury could be detected using passive avoidance test on day 7 after *** from this study indicate that weight-drop injury animal models are suitable for further screening of brain neuroprotectants and potentially are similar to those seen in human TBI.

关键词： nerve regeneration traumatic brain injury neurological severity score passive avoidance weightdrop injury model c57bl/6 mice neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：