检索结果-南通市图书馆

Paravertebral block's effect on analgesia and inflammation in advanced gastric cancer patients undergoing transarterial chemoembolization and microwave ablation

引用

World Journal of Gastrointestinal Surgery 2024年第1期16卷 196-204页

作者： Ying-Fen Xiong Ben-Zhong Wei Yu-Feng Wang Xiao-Feng Li Cong Liu Department of Anesthesiology The First Affiliated Hospital of Nanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Anesthesiology Nanjing Gulou Hospital Group Yizheng HospitalYangzhou 211400Jiangsu ProvinceChina Nuclear Medicine Department Xuzhou Cancer HospitalXuzhou 221000Jiangsu ProvinceChina Department of Radiology Xuzhou Cancer HospitalXuzhou 221000Jiangsu ProvinceChina Department of Minimally Invasive Oncology Xuzhou New Health Hospital(Xuzhou Hospital Affiliated to Jiangsu University)Xuzhou 221000Jiangsu ProvinceChina

BACKGROUND Transarterial chemoembolization(TACE)combined with microwave ablation(MWA)is an effective treatment strategy for patients with advanced gastric cancer and liver ***,it may cause severe postoperative pain and inflammatory *** paravertebral block(PVB)is a regional anesthetic technique that provides analgesia to the thoracic and abdominal *** To evaluate the effect of PVB on postoperative analgesia and inflammatory response in patients undergoing TACE combined with MWA for advanced gastric cancer and liver *** Sixty patients were randomly divided into PVB and control *** PVB group received ultrasound-guided PVB with 0.375%ropivacaine preoperatively,whereas the control group received intravenous analgesia with *** primary outcome was the visual analog scale(VAS)score for pain at 6 h,12 h,24 h,and 48 h after the *** outcomes were the dose of sufentanil used,incidence of adverse events,and levels of inflammatory markers(white blood cell count,neutrophil percentage,C-reactive protein,and procalcitonin)before and after the *** The PVB group had significantly lower VAS scores at 6 h,12 h,24 h,and 48 h after the procedure compared with the control group(P<0.05).The PVB group also had a significantly lower consumption of sufentanil and a lower incidence of nausea,vomiting,and respiratory depression than did the control group(P<0.05).Compared with the control group,the PVB group had significantly lower levels of inflammatory markers 24 h and 48 h after the procedure(P<0.05).CONCLUSION PVB can effectively reduce postoperative pain and inflammatory responses and improve postoperative comfort and recovery in patients with advanced gastric cancer and liver metastasis treated with TACE combined with MWA.

关键词： Transarterial chemoembolization microwave ablation Paravertebral block Visual analog scale Sufentanil Inflammatory markers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Camrelizumab,apatinib and hepatic artery infusion chemotherapy combined with microwave ablation for advanced hepatocellular carcinoma

引用

World Journal of Gastrointestinal Oncology 2024年第8期16卷 3481-3495页

作者： Meng-Xuan Zuo Chao An Yu-Zhe Cao Jia-Yu Pan Lu-Ping Xie Xin-Jing Yang Wang Li Pei-Hong Wu Department of Minimally Invasive Interventional Therapy Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina Department of Interventional Ultrasound Chinese General PLA HospitalBeijing 100853China Department of Medical Imaging and Interventional Radiology Sun Yatsen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Hepatic arterial infusion chemotherapy and camrelizumab plus apatinib(TRIPLET protocol)is promising for advanced hepatocellular carcinoma(Ad-HCC).However,the usefulness of microwave ablation(MWA)after TRIPLET is still *** To compare the efficacy and safety of TRIPLET alone(T-A)vs TRIPLET-MWA(TM)for *** From January 2018 to March 2022,217 Ad-HCC patients were retrospectively *** them,122 were included in the T-A group,and 95 were included in the T-M group.A propensity score matching(PSM)was applied to balance *** survival(OS)was compared using the Kaplan-Meier curve with the log-rank *** overall objective response rate(ORR)and major complications were also *** After PSM,82 patients were included both the T-A group and the T-M *** ORR(85.4%)in the T-M group was significantly higher than that(65.9%)in the T-A group(P<0.001).The cumulative 1-,2-,and 3-year OS rates were 98.7%,93.4%,and 82.0%in the T-M group and 85.1%,63.1%,and 55.0%in the T-A group(hazard ratio=0.22;95%confidence interval:0.10-0.49;P<0.001).The incidence of major complications was 4.9%(6/122)in the T-A group and 5.3%(5/95)in the T-M group,which were not significantly different(P=1.000).CONCLUSION T-M can provide better survival outcomes and comparable safety for Ad-HCC than T-A.

关键词： Hepatic arterial infusion chemotherapy Hepatocellular carcinoma Molecular targeting agent Programmed cell death protein 1 inhibitors microwave ablation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Short-term efficacy of microwave ablation in the treatment of liver cancer and its effect on immune function

引用

World Journal of Clinical Cases 2024年第18期12卷 3395-3402页

作者： Li-Jun Yao Xiao-Ding Zhu Liu-Min Zhou Li-Li Zhang Na-Na Liu Min Chen Jia-Ying Wang Shao-Jun Hu Department of Oncology Suzhou Ninth People's HospitalSuzhou 215200Jiangsu ProvinceChina Department of Rehabilitation Suzhou Xiangcheng District Rehabilitation HospitalSuzhou 215132Jiangsu ProvinceChina

BACKGROUND Hepatectomy is the first choice for treating liver ***,inflammatory factors,released in response to pain stimulation,may suppress perioperative immune function and affect the prognosis of patients undergoing *** To determine the short-term efficacy of microwave ablation in the treatment of liver cancer and its effect on immune *** Clinical data from patients with liver cancer admitted to Suzhou Ninth People’s Hospital from January 2020 to December 2023 were retrospectively ***-five patients underwent laparoscopic hepatectomy for liver cancer(liver cancer resection group)and 35 patients underwent medical image-guided microwave ablation(liver cancer ablation group).The short-term efficacy,complications,liver function,and immune function indices before and after treatment were compared between the two *** One month after treatment,19 patients experienced complete remission(CR),8 patients experienced partial remission(PR),6 patients experienced stable disease(SD),and 2 patients experienced disease progression(PD)in the liver cancer resection *** the liver cancer ablation group,21 patients experienced CR,9 patients experienced PR,3 patients experienced SD,and 2 patients experienced *** significant differences in efficacy and complications were detected between the liver cancer ablation and liver cancer resection groups(P>0.05).After treatment,total bilirubin(41.24±7.35 vs 49.18±8.64μmol/L,Pablation and liver cancer resection *** The short-term efficacy and safety of microwave ablation and laparoscopic surgery for the treatment of liver cancer are similar,but liver function recovers quickly after microwave ablation,and microwave ablation

关键词： microwave ablation Liver cancer Short-term efficacy Liver function Immunologic function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

microwave ablation of solitary T1N0M0 papillary thyroid carcinoma:A case report

引用

World Journal of Clinical Cases 2023年第20期11卷 4883-4889页

作者： Teresa Dionísio Leando Lajut Filipa Sousa Liliana Violante Pedro Sousa Department of Radiology Centro Hospitalar de Vila Nova de Gaia e EspinhoVila Nova de Gaia 4430-000Portugal Department of Sugery Centro Hospitalar de Tras-os-Montes e Alto DouroVila Real 5000-508Portugal Department of Radiology CHVNGEVila Nova de Gaia 4430-000Portugal Department of Nuclear Medicine Instituto Portugues de Oncologia do Porto Francisco GentilPorto 4200-072Portugal

BACKGROUND The gold standard treatment for papillary thyroid carcinoma is total thyroidectomy and indications for microwave thermal ablation for primary thyroid cancers have not yet been clearly established However,some patients refuse surgery and others have no indication for it,for example patients under palliative care as in this case,or cannot undergo surgery,based on their *** indications are described in the most recent Korean,North American and European *** ablation,radiofrequency ablation,and microwave ablation are similarly safe and effective,so the choice should be based on the specific competences and resources of the pertaining *** indications are Percutaneous minimally-invasive techniques;they can be useful to stop disease progression and as an alternative to surgery in patients with contraindication or who refuse *** present a case of a thyroid papillary carcinoma with 17 mm effectively treated with microwave thermal ablation and without recurrence after one year of follow *** SUMMARY The authors present a case of a 71-years-old patient with a left lobe papillary thyroid carcinoma with 13 mm×17 mm×13 mm,with no indication for thyroid surgery given the context of another cancer in palliative *** thermoablation was performed on December *** months later he repeated computed tomography(CT)scan,which showed that the tumor had *** months after ablation he underwent a positron emission tomography/CT-fluorodeoxyglucose scan,which didn’t show any evidence of hypermetabolic tumor *** This case shows microwave thermoablation can be a safe and effective alternative to surgery in patients with no conditions to undergo surgery or when they refuse *** treating the tumor,with this minimally invasive technique,we are stopping its growth and avoiding disease progression.

关键词： Thyroid carcinoma microwave ablation Thyroid nodules Papillary thyroid cancer Thyroid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of CT-Guided microwave ablation Combined with TACE on Liver Function and Survival of Patients with Primary Liver Cancer

引用

Journal of Clinical and Nursing Research 2024年第1期8卷 119-124页

作者： Bo Chen Donghong Shi Min Ai Longjiang Zhang Department of Medical Imaging Eastern Theater Command General HospitalNanjing 210002Jiangsu ProvinceChina

Objective:To explore the effect of transarterial chemoembolization(TACE)+CT-guided microwave ablation(MWA)on treating patients with primary liver ***:78 primary liver cancer cases were enrolled and divided into groups according to their assigned surgical *** control group was treated with TACE alone,and the observation group was treated with TACE+CT-guided *** efficacy of the treatment and the liver function indicators and follow-up results of the patients of the two groups were ***:The efficacy of the treatment received by the observation group was higher than that of the control ***,the patients in the observation group exhibited better improvement in liver function indicators after 3 months of ***,the survival rates of 1 and 2 years after surgery of the observation group were all higher than those of the control group(P<0.05).Conclusion:TACE combined with CT-guided MWA is more effective in treating primary liver cancer compared to TACE ***,it resulted in better improvement of liver function and long-term survival ***,this treatment regime should be popularized.

关键词： CT guidance microwave ablation TACE Primary liver cancer Liver function Survival status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

microwave ablation combined with transarterial chemoembolization containing doxorubicin hydrochloride liposome for treating primary and metastatic liver cancers

引用

Journal of Interventional Medicine 2023年第3期6卷 121-125页

作者： Qin Shi Zihan Zhang Wen Zhang Jingqin Ma Minjie Yang Jianjun Luo Lingxiao Liu Zhiping Yan Department of Interventional Radiology Zhongshan HospitalFudan UniversityShanghai200032China Shanghai Institution of Medical Imaging Shanghai200032China National Clinical Research Center for Interventional Medicine Zhongshan HospitalFudan UniversityShanghai200032China

Aims:To determine the safety and efficacy of microwave ablation(MWA)and transarterial chemoembolization(TACE)with doxorubicin hydrochloride liposome(DHL)in patients with primary liver cancer(PLC)and metastatic liver cancer(MLC).Materials and methods:The medical records of patients with primary or metastatic liver cancer who underwent MWA combined with TACE containing DHL from March 2019 to March 2022 were collected and ***-related adverse events(AEs)were *** tumor response was evaluated according to the modified RECIST *** tumor progression-free survival(LTPFS)and overall survival(OS)were calculated using the Kaplan-Meier ***:Altogether,96 patients with liver cancer were included(PLC,n=45;MLC,n=51).Forty(41.7%)patients experienced AEs during treatment,and eight(8.3%)patients developed grade 3 *** to before treatment,the serum total bilirubin level and neutrophil to lymphocyte ratio significantly increased after *** median LTPFS was 14.5 months in patients with PLC and 10.7 months in patients with *** median OS was not reached in patients with PLC or *** 1-month and 3-month disease control rates reached more than 80%in both ***:MWA combined with TACE with DHL may be a safe and effective method for the treatment of liver cancer.

关键词： Liver cancer Doxorubicin hydrochloride liposome Transarterial chemoembolization microwave ablation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Combination therapy using microwave ablation and d-mannose-chelated iron oxide nanoparticles inhibits hepatocellular carcinoma progression

引用

Acta Pharmaceutica Sinica B 2022年第9期12卷 3475-3485页

作者： Rui Cui Luo Wang Dongyun Zhang Kun Zhang Jianping Dou Linan Dong Yixuan Zhang Jiapeng Wu Longfei Tan Jie Yu Ping Liang Department of Interventional Ultrasound PLA General HospitalBeijing 100853China Department of Medical Ultrasonics the Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655China Laboratory of Controllable Preparation and App Department of Medical Ultrasound Shanghai Tenth People's HospitalTongji University School of MedicineShanghai 200072China Ultrasound Research and Education Institute Tongji University School of MedicineShanghai 200072China Laboratory of Controllable Preparation and Application of Nanomaterials Key Laboratory of CryogenicsTechnical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Despite being a common therapy for hepatocellular carcinoma(HCC),insufficient thermal ablation can leave behind tumor residues that can cause *** is believed to augment M2 inflammatory macrophages that usually play a pro-tumorigenic *** address this problem,we designed D-mannose-chelated iron oxide nanoparticles(man-IONPs) to polarize M2-like macrophages into the antitumor Ml *** vitro and in vivo experiments demonstrated that man-IONPs specifically targeted M2-like macrophages and accumulated in peri-ablation zones after macrophage infiltration was augmented under insufficient microwave ablation(MWA).The nanoparticles simultaneously induced polarization of pro-tumorigenic M2 macrophages into antitumor M1 phenotypes,enabling the transformation of the immunosuppressive microenvironment into an immunoactivating ***-MWA macrophage polarization exerted robust inhibitory effects on HCC progression in a well-established orthotopic liver cancer mouse ***,combining thermal ablation with man-IONPs can salvage residual tumors after insufficient *** results have strong potential for clinical translation.

关键词： microwave ablation Hepatocellular carcinoma Iron oxide nanoparticle Macrophage polarization Targeted therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficacy and safety of computed tomography-guided microwave ablation with fine needle-assisted puncture positioning technique for hepatocellular carcinoma

引用

World Journal of Gastrointestinal Oncology 2022年第9期14卷 1727-1738页

作者： Ming-Zhi Hao Yu-Bin Hu Qi-Zhong Chen Zhang-Xian Chen Hai-Lan Lin Department of Tumor Interventional Radiology Fujian Medical University Cancer HospitalFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina Department of Fujian Provincial Key Laboratory of Translational Cancer Medicine Fujian Cancer HospitalFuzhou 350014Fujian ProvinceChina

BACKGROUND In microwave ablation(MWA), although computed tomography(CT) scanning can overcome gas interference, it cannot achieve real-time localization. Therefore, the puncture technique is more important in CT-guided *** To compare the fine needle-assisted puncture(FNP) positioning technique and the conventional puncture(CP) technique for the safety and efficacy of CT-guided MWA in treating hepatocellular carcinoma(HCC).METHODS This retrospective study included 124 patients with 166 tumor nodules from February 2018 and June 2021. Seventy patients received CT-guided MWA under the FNP technique(FNP group), and 54 patients received MWA under the CP technique(CP group). Intergroup comparisons were made regarding local tumor progression(LTP), recurrence-free survival(RFS), overall survival(OS), and complications. The influencing variables of LTP and RFS were analyzed through univariate and multivariate *** The 1-, 2-, and 3-year cumulative incidences of LTP in the FNP group were significantly lower than those in the CP group(7.4%, 12.7%, 21.3% vs 13.7%, 32.9%, 36.4%;P = 0.038). The 1-, 2-, and 3-year RFS rates in the FNP group were significantly higher than those in the CP group(80.6%, 73.3%, 64.0% vs 83.3%,39.4%, and 32.5%, respectively;P = 0.008). The FNP technique independently predicted LTP and RFS. Minor complications in the FNP group were lower than those in the CP group(P < 0.001). The difference in median OS was insignificant between the FNP and CP groups(P = 0.229).CONCLUSION The FNP technique used in CT-guided MWA may improve outcomes in terms of LTP, RFS, and procedure-related complications for HCC.

关键词： Hepatocellular carcinoma Fine needle puncture microwave ablation Recurrence-free survival Local tumor progression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ultrasound-guided microwave ablation as a palliative treatment for mycosis fungoides eyelid involvement:A case report

引用

World Journal of Clinical Cases 2022年第17期10卷 5825-5832页

作者： Yan-Wei Chen Hai-Zhen Yang Shuang-Shuang Zhao Zheng Zhang Zhe-Ming Chen Hua-Hui Feng Mao-Hui An Ke-Ke Wang Ran Duan Bao-Ding Chen Department of Medical Ultrasound The Affiliated Hospital of Jiangsu UniversityZhenjiang 212000Jiangsu ProvinceChina

BACKGROUND Mycosis fungoides(MF)is a form of lymphoma derived from heterogeneous T cells,and eyelid involvement is extremely *** common methods to treat eyelid involvement are radiotherapy and chemotherapy,but their efficacies are ***,we report a case of advanced-stage MF eyelid involvement,propose ultrasound(US)-guided microwave ablation(MWA)therapy and present a literature *** SUMMARY A male patient was admitted to our hospital in June 2018 and diagnosed with MF via radiological and histopathological *** patient’s condition was not well controlled by various conventional ***-guided MWA was performed to relieve the patient’s symptoms and improve his quality of life,showing satisfactory *** Eyelid involvement is one of the most troublesome clinical problems for advanced-stage MF *** is the first report on the use of US-guided MWA as a palliative therapy for MF eyelid involvement;the treatment successfully relieved the patient’s clinical symptoms and reduced his anxiety *** study sheds new light on methods for improving the clinical management of eyelid involvement in MF.

关键词： Mycosis fungoides Cutaneous lymphomas Eyelid involvement microwave ablation Palliative care Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of microwave ablation on serum Golgi protein 73 in patients with primary liver cancer

引用

World Journal of Gastroenterology 2022年第29期28卷 3971-3980页

作者： Zheng-Ju Xu Mei-Juan Wei Xiao-Man Zhang Hui-Guo Liu Jin-Piao Wu Jin-Fa Huang Yong-Fei Li Zhi-Jie Huang Yan-Yan Yan The Liver Disease Center The 910th Hospital of the PLA Joint Logistics Support ForceQuanzhou 362000Fujian ProvinceChina Central Laboratory Decheng HospitalQuanzhou 362104Fujian ProvinceChina Central Laboratory of Clinical Hepatology The 910th Hospital of the PLA Joint Logistics Support ForceQuanzhou 362000Fujian ProvinceChina

BACKGROUND microwave ablation(MWA)is an effective treatment option for patients with primary liver ***,it has been reported that the MWA procedure induces a hepatic inflammatory response and injury,which may negatively affect the efficacy of *** such,the discovery of reliable markers to monitor the patient’s response to MWA is *** protein 73(GP73)has been shown to be associated with chronic liver *** date,the potential value of serum GP73 in the dynamic monitoring during MWA of liver cancer remains *** To examine the effects of MWA on the serum levels of GP73 in patients with primary liver *** A total of 150 primary liver cancer patients with a single small lesion(≤3 cm in diameter)were retrospectively enrolled spanning the period between January 2016 and October *** of the patients received MWA for the treatment of primary liver *** GP73,alpha-fetoprotein(AFP),and widely used liver biochemical indicators[serum albumin,total bilirubin(TBIL),alanine aminotransferase(ALT),and aspartate aminotransferase(AST)]were compared before MWA and at different time points,including 1,2,and 4 wk following the ablation *** Complete tumor ablation was achieved in 95.33%of the patients at 1 mo after *** 1-,2-,and 3-year disease-free survival rates were 74.67%,59.33%,and 54.00%,*** serum AFP levels were significantly decreased at 1,2,and 4 wk after MWA;they returned to the normal range at 12 wk after MWA;and they remained stable thereafter during follow-up in those cases without *** contrast,the serum GP73 levels were significantly increased at 1 and 2 wk after *** serum GP73 levels reached the peak at 2 wk after MWA,started to decline after hepatoprotective treatment with glycyrrhizin and reduced glutathione,and returned to the pretreatment levels at 12 and 24 wk after ***,the changes of serum GP73 in response to MWA were similar to those of TBIL,ALT,and ***

关键词： Liver cancer microwave ablation ablation therapy Golgi protein 73 Biomarker Liver injury

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：