检索结果-南通市图书馆

Association between serum cartilage oligomeric matrix protein and coronary artery calcification in maintenance hemodialysis patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2020年第2期17卷 67-73页

作者： Lahati HA Jun-Bao SHI Hai-Yi YU Kun YANG Hai-Ning WANG Fang-Fang WANG Jiang-Li HAN Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesKey Laboratory of Molecular Cardiovascular ScienceMinistry of EducationBeijing Key Laboratory of Cardiovascular Receptors ResearchBeijingChina Department of Nephrology Peking University Third HospitalBeijingChina Department of Endocrinology Peking University Third HospitalBeijingChina

Background Coronary artery calcification(CAC)is common in end-stage renal disease(ESRD)patients,and the extent of CAC is closely related to cardiovascular outcomes in ESRD *** oligomeric matrix protein(COMP),as a component of the vascular matrix,has been found to be an inhibitor of arterial calcification in basic ***,there is no clinical research on the correlation between COMP and CAC in maintenance hemodialysis(MHD)*** aim of this study was to explore the relationship between serum COMP levels and CAC and cardiovascular events in MHD *** Serum COMP levels were compared between 54 MHD patients and 66 healthy *** patients were then divided into three groups according to the tertiles of the concentration of COMP level and were followed up for major adverse cardiac events(MACEs),which were defined as a combined end point of new onset angina pectoris,nonfatal myocardial infarction,heart failure,coronary artery revascularization,hospitalization due to angina pectoris and all-cause *** CAC score was calculated based on computed tomography *** The serum COMP level in MHD patients was significantly higher than that in the general population[984.23(248.43-1902.61)ng/mL vs.219.01(97.26-821.92)ng/mL,P<0.01].Serum COMP levels were positively correlated with CAC(r=0.313,P=0.021)and serum parathyroid hormone in MHD patients(r=0.359,P<0.01).Linear regression suggested that after adjusting for age,fasting blood glucose(Glu)and glycosylated hemoglobin(HbAlc),CAC score was an independent predictor in the final model for COMP level(β=0.424,t=3.130,P<0.01).The receiver operating characteristic(ROC)curve showed that COMP≥994 mg/mL had 68.0%sensitivity and 72.4%specificity for the prediction of severe CAC[area under the curve(AUC):0.674,P=0.030,95%CI:0.526-0.882].After a median follow-up of 16 months(8-24 months),there was no difference in the incidence rate of MACEs between the upper,middle and lower serum COMP gr

关键词： Biomarker Cartilage oligomeric matrix protein Coronary artery calcification maintenance hemodialysis

Acupoint Selection Standards of Auricular Therapy in the Treatment of maintenance hemodialysis Insomnia Based on Data Mining

在线全文

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2024年第1期10卷 53-64页

作者： Jun-Xin Wang Bing-Qian Zou Yu-Feng Chen Cheng-Long Wang Wei-Hong Li Xue-Ling Ma Xiang-Di Liu Department of TCM Nursing School of NursingBeijing University of Chinese MedicineBeijingChina Department of Healthcare Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesP.R.China Pharmacology of Integrated Chinese and Western Medicine School of Traditional Chinese MedicineBeijing University of Chinese MedicineBeijingChina Beijing Key Laboratory of TCM Syndrome and Formula School of Traditional Chinese MedicineBeijing University of Chinese MedicineBeijingChina Key Laboratory of TCM Syndrome and Formula School of Traditional Chinese MedicineBeijing University of Chinese MedicineMinistry of EducationBeijingChina

Background:Insomnia is a high-incidence complication in patients undergoing maintenance hemodialysis(MHD).Auricular therapy can effectively improve sleep with few adverse *** selection affects the impact of auricular ***,there is currently a lack of analysis on the standards of acupoint *** study used data mining technology to investigate the acupoint selection principles and characteristics of auricular therapy for the treatment of MHD-related ***:The objective of the study is to explore the standards of acupoint selection in auricular therapy for the treatment of MHD-related insomnia through data mining *** and Methods:We searched three English(PubMed,WOS,and Embase)and four Chinese(CNKI,VIP,Wangfang,and CBM)databases for studies on auricular therapy for MHD-related insomnia from self-establishment to November 14,***:Eighty-one publications were involved,which included 33 *** most common auricular points in patients with MHD-related insomnia were the Shenmen,heart,and kidney *** applications involved the visceral,nervous system,and specific *** effective clusters and two clusters were obtained through cluster analysis,including specific auricular points for insomnia,such as the multi-dream area,neurasthenia area,deep sleep point,and anterior ear *** network analysis showed that the core auricular acupoint combinations for the intervention of MHD-related insomnia were Shenmen with kidney,Shenmen with heart,heart with kidney,heart with Shenmen,and heart and Shenmen with ***:The selection of auricular points for the treatment of MHD-related insomnia was guided by the heart theory of traditional Chinese *** treatment attaches importance to the use of the multi-dream area,neurasthenia area,and other acupoints.

关键词： Acupoint selection standards auricular therapy data mining insomnia maintenance hemodialysis

Mediating role of social support in dysphoria,despondency,and quality of life in patients undergoing maintenance hemodialysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第3期14卷 409-420页

作者： Xiang Zhou Hong Jiang Yi-Peng Zhou Xiao-Yu Wang Hai-Yan Ren Xue-Fei Tian Qing-Qing Zhang Department of Nephrology People’s Hospital of Xinjiang Uygur Autonomous RegionXinjiang Clinical Research Center for Kidney DiseaseUrumqi 832000Xinjiang Uygur Autonomous RegionChina Department of Endocrinology and Metabolism People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi 832000Xinjiang Uygur Autonomous RegionChina Section of Nephrology Department of Internal MedicineYale University School of MedicineNew HavenCT 06510United States

BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing maintenance hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can significantly improve the physical and mental well-being of patients undergoing ***,there is limited research on how social support mediates the relationship between dysphoria,despondency,and overall QOL in patients undergoing *** is imperative to investigate this mediating effect to mitigate dysphoria and despondency in patients undergoing MHD,ultimately enhancing their overall *** To investigate the mediating role of social support in relationships between dysphoria,despondency,and QOL among patients undergoing *** Participants comprised 289 patients undergoing MHD,who were selected using a random sampling *** Social Support Rating Scale,Self-Rating Anxiety Scale,Self-Rating Depression Scale,and QOL Scale were *** analysis was performed to examine the associations between social support,dysphoria,despondency,and QOL in patients undergoing *** assess the mediating impact of social support on dysphoria,despondency,and QOL in patients undergoing MHD,a bootstrap method was *** Significant correlations among social support,dysphoria,despondency,and quality in patients undergoing MHD were observed(all P<0.01).Dysphoria and despondency negatively correlated with social support and QOL(P<0.01).Dysphoria and despondency had negative predictive impacts on the QOL of patients undergoing MHD(P<0.05).The direct effect of dysphoria on QOL was statistically significant(P<0.05).Social support mediated the relationship between dysphoria and QOL,and this mediating effect was significant(P<0.05).Similarly,the direct effect of despondency on QOL was significant(P<0.05).Moreover,social support played a mediating role between despondency and QOL,with a significant mediating effect(P<0.05).CONCLUSION These find

关键词： maintenance hemodialysis Social support Dysphoria Despondency Quality of life Mediating effect

Construction and verification of a model for predicting fall risk in patients with maintenance hemodialysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Nursing 2024年第4期11卷 387-394页

作者： Yue Liu Yan-Li Zeng Shan Zhang Li Meng Xiao-Hua He Qing Tang College of Nursing Chengdu University of Traditional Chinese MedicineChengduSichuan 610075China Blood Purification Center Sichuan Academy of Medical Science and Sichuan Provincial People’s HospitalChengduSichuan 610072China

Objective:To construct a risk prediction model for fall in patients with maintenance hemodialysis(MHD)and to verify the prediction effect of the ***:From June 2020 to December 2020,307 patients who underwent MHD in a tertiary hospital in Chengdu were divided into a fall group(32 cases)and a non-fall group(275 cases).Logistic regression analysis model was used to establish the influencing factors of the ***–Lemeshow and receiver operating characteristic(ROC)curve were used to test the goodness of fit and predictive effect of the model,and 104 patients were again included in the application research of the ***:The risk factors for fall were history of falls in the past year(OR=3.951),dialysis-related hypotension(OR=6.949),time up and go(TUG)test(OR=4.630),serum albumin(OR=0.661),frailty(OR=7.770),and fasting blood glucose(OR=1.141).Hosmer–Lemeshow test was P=0.475;the area under the ROC curve was 0.907;the Youden index was 0.642;the sensitivity was 0.843;and the specificity was ***:The risk prediction model constructed in this study has a good effect and can provide references for clinical screening of fall risks in patients with MHD.

关键词： construction fall maintenance hemodialysis risk prediction model verification

Analysis of current status of and barriers to exercise participation among patients on maintenance hemodialysis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Nursing 2024年第2期6卷 96-102页

作者： Xin TIAN Xiuli LI Jianhua DENG Department of Traditional Chinese Medicine Air Force Medical CenterPLABeijingChina Department of Nephrology Dongfang HospitalBeijing University of Chinese MedicineBeijingChina

Objective:The objective of this study was to analyze the current status of barriers to exercise participation(EP)among patients on maintenance hemodialysis(MHD).Materials and Methods:A cross-sectional study was conducted on 277 outpatients undergoing MHD in 2 tertiary first-class hospitals in Beijing from February 2023 to June 2023 who were selected using convenience sampling *** data of patients on MHD were collected using the general information questionnaire,Physical Activity Rating Scale,Exercise Benefits/Barriers Scale(EBBS),and Exercise Self-Efficacy Scale(ESES).The relationship between EP and barriers to EP was analyzed through univariate and multivariate linear regression ***:Patients on MHD had a low exercise volume score of 13.71±0.68 points and a medium EBBS score of 63.36±0.40 *** logistic analysis showed that exercise volume was significantly related to the following four aspects,including low monthly household income per capita(odds ratio[OR]=86.741,95%confidence interval[CI][1.164-6.465],P=0.042),primary underlying disease of diabetic nephropathy(OR=45.993,95%CI[1.353-1.564],P=0.033),the belief that“fatigue in lower extremities hinders exercise”(OR=4.697,95%CI[1.127-19.585],P=0.034),and the belief that“physical exercise bringing optimistic and positive life attitude”(OR=0.074,95%CI[0.007-0.830],P=0.035).Conclusions:Since patients on MHD had low physical exercise volume,the health-care provider should pay more attention on the controllable factors that affect the EP of patients on ***,feasible and effective intervention measures can be formulated based on ESES in clinical nursing.

关键词： Barrier(s) exercise rehabilitation exercise maintenance hemodialysis physical activity renal dialysis

The effect of Levocarnitine on nutritional status and lipid metabolism during long-term maintenance hemodialysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2010年第3期22卷 203-207页

作者： Rong-Guo Fu1,Li Wang1,Jian-Ping Zhou2,Feng Ma1,Xiao-Dan Liu1,Heng Ge1,Jun Zhang3 1.Department of Nephrology 2.Department of Pediatrics 3.Department of Digestive Internal Medicine,the Second Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an,710004,China Department of Nephrology Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China Department of Pediatrics Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China Department of Digestive Internal Medicine Second Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710004 China

Objective To investigate the effect of Levocarnitine on lipid metabolism and nutritional status of maintenance hemodialysis(MHD)patients and possible *** A total of 40 MHD patients [mean age(53.5±7.1)years] who underwent normal hemodialysis more than 6 months were randomly classified into two groups,Levocarnitine supplemented group(LS-G)(n=20;Levocarnitine supplementation after each normal hemodialysis session,at a dose of 1.0 g/day by intravenous administration)and control group(C-G)(n=20;normal hemodialysis).Before treatment,one month and three months after treatment we respectively measured or observed the following items,the tolerance to hemodialysis,carnitine level in plasma,C-reactive protein,IL-6,TNF-α,percentage of neutrophil,and some relevant nutritional parameters,such as lipid profile,transferrin,total protein,albumin and prealbumin *** analysis was conducted between the two *** In LS-G three months after treatment,the levels of carnitine,hemoglobin,and prealbumin in plasma were significantly increased(Pmaintenance hemodialysis patients with Levocarnitine *** this improvement is related to the decrease of inflammatory factors.

关键词： inflammatory factors nutritional status maintenance hemodialysis lipid metabolism Levocarnitine

Current status and influencing factors of post-traumatic growth in maintenance hemodialysis

在线全文

学校读者我要写书评

暂无评论

International Journal of Nursing Sciences 2017年第4期4卷 362-366页

作者： Chuyun Cui Kuijie Wang Jinye An Changde Jin Tianjin University of Traditional Chinese Medicine TianjinChina Tianjin First Center Hospital TianjinChina The Third Hospital of Hebei Medical University ShijiazhuangChina

Objective:To study the post-traumatic growth level and influencing factors in patients with maintenance ***:A total of 179 patients receiving maintenance hemodialysis from a third-level grade A hospital in Tianjin,China were investigated using Post-traumatic Growth Inventory(PTGI),Perceived Social Support Scale,and Medical Coping Modes ***:The total score for the PTGI was 53.73±*** linear regression analysis showed that social support,coping style,marital status,and family income significantly influenced the post-traumatic growth level in patients undergoing maintenance *** factors explained 41.4%of the ***:Medical staff should help patients under maintenance hemodialysis to fulfill their potentials by boosting the level of social support and to effectively cope with internal *** addition,nursing staff should provide relevant psychological health education to patients to improve their post-traumatic growth.

关键词： maintenance hemodialysis Patients Post-traumatic growth Root cause analysis

Effects of Lanthanum Carbonate on Vascular Calcification in Elderly maintenance hemodialysis Patients

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 2015年第4期35卷 508-513页

作者：王晓慧张新穆昌军何泳彭清平杨国胜李明梅刘端李静丁国华 Department of Nephrology Renmin Hospital of Wuhan University Department of Nephrology Wuhan Fifth Hospital

Summary： The effect of lanthanum carbonate on abdominal aortic calcification （AAC） in the elderly maintenance hemodialysis （MHD） patients was investigated. Fifty-four cases subjected to routine MHD complicated with skin pruritus admitted to our hospital were selected and randomly divided into case group （n=28） and control group （n=26）. The control group was given routine MHD alone. The case group was given lanthanum carbonate additionally on the basis of routine MHD. The changes of itching degrees at first and third month, and serum calcium, phosphorus, calcium-phosphorus products, intact parathyroid hormone （iPTH） levels and AAC scores at third month after treatments were compared be- tween the two groups. The correlation between calcium-phosphorus products and AAC scores was also analyzed. There was no significant difference in the baseline of blood urea nitrogen （BUN）, serum creatinine （Scr）, uric acid, albumin, hemoglobin, C reactive protein （CRP）, low density lipoprotein （LDL）, high density lipoprotein （HDL）, triglyceride, total cholesterol between case group and control group （P〉0.05 for all）. There was also no significant difference in the baseline itching scores between the case group and the control group （P〉0.05）. At 1st and 3rd month after treatment, the itching scores in the case group were 14.2±3.2 and 10.5±2.3, respectively, which were significantly lower than the baseline and those in the control group （P〈0.05 for all）. At 1 st and 3rd month after treatment, the itching scores in the control group were 23.6v5.9 and 24.8±6.3, respectively, which were significantly higher than the baseline （P〈0.05）. There was no significant difference in the baseline of serum calcium, phos- phorus, calcium-phosphorus products, iPTH levels between the case group and control group （P〉0.05）. At 3rd month after treatment, serum phosphorus, calcium-phosphorus products and iPTH levels in the case group were decreased significantly as compared with the baseline （P〈0.05）, and t

关键词： maintenance hemodialysis lanthanum carbonate intact parathyroid hormone serum phosphorus abdominal aortic calcification

Glycated albumin may be a choice, but not an alternative marker of glycated hemoglobin for glycemic control assessment in diabetic patients undergoing maintenance hemodialysis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2013年第17期126卷 3295-3300页

作者： CHEN Fengskun SUN Xue-feng ZHANG Dong CUI Shao-yuan CHEN Xiang-mei WEI Ri-bao LU Ju-ming LI Ji-jun LIU Wen-hu ZHANG Dong-liang ZHANG Zhi-min Department of Nephrology First Affiliated Hospital of People's Liberation Army General Hospital Beijing 100048 China Institute of Nephrology People's Liberation Army General Hospital Beijing 100853 China Department of Endocrinology People's Liberation Army General Hospital Beijing 100853 China Department of Nephrology Affiliated Beijing Friendship Hospital of Capital Medical University Beijing 100050 China Department of Nephrology People's Liberation Army the 309th Hospital Beijing 100091 China

Background It has been suggested that glycated hemoglobin （HbAlc） underestimate the actual glycemic control levels in maintenance hemodialysis （MHD） patients, because of anemia and the using of erythropoietin （EPO）; it was recommended that glycated albumin （GA） should be an alternative marker. Therefore, the assessment performances of glycemic control were compared between GA and HbAlc in this research by referring to mean plasma glucose （MPG） in diabetes mellitus （DM） patients undergoing MHD or not. Methods MPG was calculated according to the data registered at enrollment and follow-up 2 months later and corresponding HbAlc, albumin （ALB）, GA, etc. were measured in 280 cases. A case-control study for comparing GA and HbAlc was done among the groups of MHD patients with DM （n=88） and without DM （NDM; n=90）, and non-MHD ones with DM （n=102） using MPG for an actual glycemic control standard. Results In these 3 groups, only for DM patients＇（whether undergoing MHD or not）, GA and HbAlc correlated with MPG significantly （P 〈0.01）. Through linear regression analysis, it could be found that the regression curves of GA almost coincided in MHD and non-MHD patients with DM, because the intercepts （2.418 vs. 2.329） and slopes （0.053 vs. 0.057） were very close to each other. On the contrary, regression curves of HbAlc did not coincide in the two groups, because variance of the slopes （0.036 vs. 0.052） were relatively large. Through comparing receiver operating characteristic （ROC） areas under the curve （AUC）, it could be understood that the assessment performances of GA and HbAlc in MHD patients were lower than those in non-MHD ones, and assessment performance of HbAlc in MHD patients was better than GA （P 〈0.05）. In addition, the effects of Hb and EPO dose on HbAlc, or that of ALB on GA were unobvious in our study. Conclusions Actual glycemic control level in MHD patients with DM may be underestimated by HbAlc, and it could be avoided by GA; however, glycemic evaluating perfo

关键词： maintenance hemodialysis diabetes mellitus glycated albumin glycated hemoglobin