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检索条件"主题词=frequent targets"
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Mediator complex components are frequent targets for genetic alterations in various types of human cancer
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Journal of Genetics and Genomics 2017年 第12期44卷 587-591页
作者: Libin Deng Cheng Zhang Duling Miao Xiaoli Tang Shiwen Luo Hong-Bo Xin Huidong Shi Institute of Translational Medicine Nanchang UniversityNanchang 330031China Medical School of Nanchang University Nanchang 330031China Center for Experimental Medicine The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Biochemistry and Molecular Biology Medical College of GeorgiaAugusta UniversityAugustaGA 30912USA Georgia Cancer Center Augusta UniversityAugustaGA 30912USA
The Mediator co-activator complex is a highly conserved,multisubunit protein complex required for gene transcription by RNA polymerase Ⅱ(RNAPⅡ)in all eukaryotes(Allen and Taatjes,2015).This complex,which consist... 详细信息
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