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Systemic Lupus Erythematosus Complicated with femoral head ischemic necrosis Treated by Chinese Medicine Therapy for Activating Blood and Dredging Collaterals Method

引用

Chinese Journal of Integrative Medicine 2011年第3期17卷 105-110页

作者：汪卫于健宁陶筱娟 Departement of Rheumatology Immunology and Nephropathy Zhejiang Provincial Hospital of Integrated Chinese and Western Medicine

Objective：To observe the effect and mechanism of Chinese medicine therapy for activating blood and dredging collaterals（ABDC） on treating systemic lupus erythematosus complicated with avascular necrosis of the femoral head（SLE-ANFH）.Methods：Thirty-four patients（51 joints） with SLE-ANFH were assigned by a random number table to two groups：22 patients（32 joints） in the treatment group and 12 patients （19 joints） in the control *** received Western medical conventional treatment for anti-inflammation and immunosuppression,but an additional Chinese medicine decoction prescribed based on ABDC principle was administered to patients in the treatment *** observation on the patients＇ condition and therapeutic effect lasted for 3 ***：The patients＇ conditions in the two groups,as assessed by Association for Research Circulation Osseous（ARCO） staging,were similar before *** treatment,comparison between groups showed significant difference（P0.05）,and the raised Harris functional scores in the treatment group were higher than that in the control group（P0.01）.The post-treatment symptom improving rate in the treated group was 72.73%,which was higher than that in the control group（50.00%,P0.05）.Moreover,the former was superior in improving hematologic and hemorrheologic parameters in terms of prolonging activated partial thromboplastin time,lowering whole blood middle/low shear viscosity,and plasma viscosity（P0.05 or P0.01）. Two patients in the control group but none in the treatment group received hip joint replacement operation during the observation ***：Chinese medicine ABDC therapy could effectively alleviate clinical symptoms and improve joint function of patients with *** mechanism may be related to its effects on improving high coagulation manner and trend for getting embolism.

关键词： systemic lupus erythematosus femoral head ischemic necrosis Chinese medicine activating blood and dredging collaterals

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