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Living mycelium composites discern weights via patterns of electrical activity

Journal of Bioresources and Bioproducts 2022年第1期7卷 26-32页

作者： Andrew Adamatzky Antoni Gandia Unconventional Computing Laboratory University of the West of EnglandBristolUK Institute for Plant Molecular and Cell Biology CSIC-UPVValenciaSpain

Fungal construction materials-substrates colonised by mycelium-are getting increased recog-nition as viable ecologically friendly alternatives to conventional building materials.A function-ality of the constructions made from fungal materials would be enriched if blocks with living mycelium,known for their ability to respond to chemical,optical and tactile stimuli,were *** investigated how large blocks of substrates colonised with mycelium of Ganoderma resinaceum responded to stimulation with heavy *** analysed details of the electrical re-sponses to the stimulation with weights and show that ON and OFF stimuli can be discriminated by the living mycelium composites and that a habituation to the stimulation *** of the results cast in the reporting on changes in electrical spiking activity of mycelium bound composites in response to a heavy loads.

关键词： Fungi Unconventional materials electrical activity Bionics

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Structured PDMS Chambers for Enhanced Human Neuronal Cell activity on MEA Platforms

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Journal of Bionic Engineering 2012年第1期9卷 1-10页

作者： Joose Kreutzer Laura Yla-Outinen Paula Karna Tiina Kaarela Jarno Mikkonen Heli Skottman Susanna Narkilahti Pasi KaUio Department of Automation Science and Engineering Tampere University of Technology Korkeakoulunkatu 3 33720 Tampere Finland BioMediTech Biokatu 10 33520 Tampere Finland NeuroGroup Institute of Biomedical Technology University of Tampere Biokatu 12 33520 Tampere Finland The Science Center of Pirkanmaa Hospital District Biokatu 12 33521 Tampere Finland Department of Psychology University of Jyvdskyld Ylistonmgientie 33 40500 Jyvdskyla Finland

Structured poly（dimethylsiloxane）（PDMS） chambers were designed and fabricated to enhance the signaling of human Embryonic Stem Cell （hESC） - derived neuronal networks on Microelectrode Array （MEA） platforms. The structured PDMS chambers enable cell seeding on restricted areas and thus, reduce the amount of needed coating materials and cells. In addition, the neuronal cells formed spontaneously active networks faster in the structured PDMS chambers than that in control chambers. In the PDMS chambers, the neuronal networks were more active and able to develop their signaling into organized signal trains faster than control cultures. The PDMS chamber design enables much more repeatable analysis and rapid growth of functional neuronal network in vitro. Moreover, due to its easy and cheap fabrication process, new configurations can be easily fabricated based on investigator requirements.

关键词： cell culturing electrical activity human embryonic stem cells microelectrode array poly(dimethylsiloxane)

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孕兔子宫平滑肌自发电活动的研究

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中华生殖与避孕杂志 1986年第3期 45-48页

作者：李钦选王合轩新乡医学院生理教研室

用不锈钢记录电极对妊娠中期、妊娠晚期、分娩期和分娩后的48只家兔子宫平滑肌自发电活动进行在体和离体测定的记录表明,从妊娠中期至分娩后期,自发电活动存在着一定的规律性:先以单波为主(62.6±6.3个/10分),偶有爆发波(2.5±1.5个/10... 详细信息

用不锈钢记录电极对妊娠中期、妊娠晚期、分娩期和分娩后的48只家兔子宫平滑肌自发电活动进行在体和离体测定的记录表明,从妊娠中期至分娩后期,自发电活动存在着一定的规律性:先以单波为主(62.6±6.3个/10分),偶有爆发波(2.5±1.5个/10分);随着妊娠的进程,单波频率减低,爆发波频率增加,分娩期爆发波频率最高(10.8±1.6个/10分);分娩后,则爆发波逐渐减少,而单波逐渐增加。另外,爆发波的产生均伴随着宫内压的升高,且先于宫内压的升高。

关键词： Rabbit Myometrium electrical activity Intrauterine pressure

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SPONTANEOUS electrical WAVEFORMS IN IMMATURE AND OLDER GUINEA-PIG PROSTATES

SPONTANEOUS ELECTRICAL WAVEFORMS IN IMMATURE AND OLDER GUINE...

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第十五届国际药理学大会

作者： Exintaris Betty Dey Anupa Nguyen Dan -Thanh Lang Rick Prostate Research Co - operative Victorian College of Pharmacy Monash University Parkville VIC Prostate Research Co - operative Victorian College of Pharmacy Monash University Parkville VIC Prostate Research Co - operative Victorian College of Pharmacy Monash University Parkville VIC Department of Physiology Monash University Clayton VIC

＜正＞ Objective: To characterise the spontaneous electrical activity in prostates of immature and older guinea - pigs. Methods: Prostates were removed from guinea pigs（300 - 1200g） killed humanely. electrical activity from the guinea - pig prostate was recorded using intracellular microelectrodes. Results: Four types of electrical activity were recorded in the guinea - pig prostate. In young animals the majority of electrical recordings comprised of slow wave activity （88 %） which consisted of a depolarising component with several superimposed nifedipinesensitivespikes （n = 36）. Pacemaker activity consisted of a simple waveform of alternating depolarising and repolarising phases and was recorded in 5% of cells;the remaining cells exhibited spike potential discharge （7 % ）. In contrast, the most prevalent electrical activity recorded in the older prostates （56% ） was spike potentials （n = 22）. Slow wave activity was recorded in 28 % of cells （n = 11）. standard transient depolarisations comprised 15% of all electrical recordings and pacemaker potentials were not observed. Conclusion: With age. there is a change in the proportion of cells exhibiting slow wave activity.

关键词： Prostate electrical activity

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electrical activities of neural systems exposed to sinusoidal induced electric field with random phase

Electrical activities of neural systems exposed to sinusoida...

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第四届全国神经动力学学术会议

作者：都琳曹子露雷佑铭邓子辰 School of Nature and Applied Science Northwestern Polytechnical University

The brain neural system is often disturbed by electromagnetic and noise environments, and research on dynamic response of its interaction has received extensive attention. This paper investigates electrical activity of Morris–Lecar neural systems exposed to sinusoidal induced electric field(IEF) with random phase generated by electromagnetic effect. By introducing a membrane depolarization model under the effect of random IEF,transition state of firing patterns, including Mix-Mode Oscillations with layered inter-spike intervals(ISI) and intermittency with a power law distribution in probability density function of ISI, is obtained in a single neuron. Considering the synergistic effects of frequency and noise, coherence resonance is performed by phase noise of IEF under certain parameter conditions. For the neural network without any internal coupling, we demonstrate that synchronous oscillations can be induced by IEF coupling, and suppression of synchronous spiking is achieved effectively by phase noise of IEF. Results of the study enrich the dynamical response to electromagnetic induction and provide insights into mechanisms of noise affecting information coding and transmission in neural systems.

关键词： induced electric field random phase electrical activity transition coherence resonance synchronous suppression

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