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Delivered dose verification for Lung Cancer Stereotactic Body Radiotherapy Using Cone-Beam CT

Journal of Cancer Therapy 2021年第7期12卷 453-459页

作者： Yechao Feng Xi Liu Xiang Pan Chang Hu Ning Zhan Zongda Zhu Zhenxiang Deng Department of Radiation Oncology Hunan Academy of Traditional Chinese Medicine Affiliated Hospital Changsha China School of Medical Information and Engineering Guangdong Pharmaceutical University Guangzhou China Guangdong Province Precise Medicine and Big Data Engineering Technology Research Center for Traditional Chinese Medicine Guangzhou China Department of Radiation Oncology Yunnan Tumor Hospital The Third Affiliated Hospital of Kunming Medical University Kunming China The Second Af?liated Hospital of Hainan Medical University Haikou China Department of Radiation Oncology School of Medicine Xiang’an Hospital of Xiamen University Xiamen University Xiamen China

Purpose: Verified the delivered dose distribution of lung cancer Stereotactic Body Radiotherapy (SBRT) using the cone-beam CT images. Methods: Twenty lung cancer patients who underwent SBRT with 100 CBCT images were enrolled in this study. Delivered dose distributions were recalculated on CBCT images with the deformed and non-deformed methods, respectively. The planned and delivered dose distributions were compared using the dose-volume histograms. Results: The delivered target coverage (V100) per patient inside target volume deviated on average were 0.83% ± 0.86% and 1.38% ± 1.40% for Pct vs. Pcbct and Pct

关键词： Lung Cancer Stereotactic Body Radiotherapy Cone Beam CT dose verification

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Research Progress of Two-d imensional Matrix Detectors in IMRT dose verification

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Proceedings of Anticancer Research 2021年第3期5卷 30-33页

作者： Yufen Shang Yuqing Xu Fang Wang Department of Radiophysics Technology Dezhou’s Second People's HospitalDezhou 253000China Department of Burns Dezhou’s Second People's HospitalDezhou 253000China Department of Oncology Dezhou’s Second People's HospitalDezhou 253000China

With the continuous development of science and technolog ies in China,radiotherapy technology in medical field has been very significant ly developing,and intensity modulated radiation therapy(IMRT)technology has been the most widely *** paper first introduces the components and types of two-dimensional matrix detector,two-dimensional ionization chamber matrix detector and two-dimensional semiconductor matrix detector,then analyzes the dosimetric characteristics of the two-dimensional matrix *** the end,the various applications of the two-dimensional matrix detector are analyzed and discussed in *** paper aims to promote the two-dimensional matrix detector’s development in the field of radiotherapy in China.

关键词： Two dimensional matrix detector Intensity modulated radiation therapy technology dose verification

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Application of Statistical Process Control for Setting Action Thresholds as Quality Assurance of dose verifications in External Beam Radiotherapy

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2022年第1期11卷 22-35页

作者： Philip Kioko Ndonye Samuel Nii Adu Tagoe Oncology & Cancer Treatment Centre The Nairobi Hospital Nairobi Kenya School of Biomedical & Allied Health Sciences University of Ghana/Korle Bu Teaching Hospital Accra Ghana

Purpose: To test the concept of Statistical Process Control (SPC) as a Quality Assurance (QA) procedure for dose verifications in external beam radiation therapy in conventional and 3D Conformal Radiotherapy (3D-CRT) treatment of cervical cancer. Materials and Methods: A study of QA verification of target doses of 198 cervical cancer patients undergoing External Beam Radiotherapy (EBRT) treatments at two different cancer treatment centers in Kenya was conducted. The target doses were determined from measured entrance doses by the diode in vivo dosimetry. Process Behavior Charts (PBC) developed by SPC were applied for setting Action Thresholds (AT) on the target doses. The AT set was then proposed as QA limits for acceptance or rejection of verified target doses overtime of the EBRT process. Result and Discussion: Target doses for the 198 patients were calculated and SPC applied to test whether the action limits set by the Process Behavior Charts could be applied as QA for verified doses in EBRT. Results for the two sub-groups of n = 3 and n = 4 that were tested produced action thresholds which are within clinical dose specifications for both conventional AP/PA and 3D-CRT EBRT treatment techniques for cervical cancer. Conclusion: Action thresholds set by SPC were within the clinical dose specification of ±5% uncertainty for both conventional AP/PA and 3D-CRT EBRT treatment techniques for cervical cancer. So the concept of SPC could be applied in setting QA action limits for dose verifications in EBRT.

关键词： Quality Assurance Statistical Process Control Action Thresholds dose verification External Beam Radiation Therapy

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dose Distribution verifications of IMRT for NPC

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2009年第5期29卷 673-676页

作者：李勤李良韩军梁志文 Cancer Center Union HospitalTongji Medical CollegeHuazhong University of Science and Technology

In order to explore a dose distribution verification procedure of intensity modulated radiation therapy （IMRT） for nasopharyngeal carcinoma （NPC） and establish its evaluation criteria, we performed 35 two-dimensional （2D） patient-specific IMRT verifications over the year i006. The percent of pixels passing 7 and the normalized agreement test （NAT） index were mainly used to represent the agreement between the measured and computed dose distributions with three criteria （2%/2 mm, 3%/3 mm and 5%/3 mm） as recommended in the literature. The results were that all cases passed through verifications with three criteria except that the NAT index of one case was beyond the limitation, and the three tolerance levels of 2%/2mm, 3%/3 mm and 5%/3 mm produced similar clinical verification results but led to different percent of pixels passing Y and NAT index. Our data showed that the percent of pixels passing y and the NAT index were complementary to evaluate future IMRT verifications as two significant metrics. Due to the influence of the noise and the trait of the software, we considered an IMRT plan as acceptable in case of the percent ofpixels passing y 〉95% and the NAT index 〈5 with the 5%/3 mm criteria for IMRT patient-specific quality assurance （QA）.

关键词： dose distribution dose verification intensity modulated radiation therapy

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Evaluation of photon beam dose calculation accuracy of treatment planning systems using in vivo dosimetry

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Oncology and Translational Medicine 2016年第5期2卷 234-238页

作者： Mohamed Ibrahim Wahib M.Attia Khaled M.Elshahat Radiation Oncology Department El Hussein Hospital Al Azahr University Physics Department Faculty of Sciences Suez Canal University

Objective The treatment planning system currently represents one of the basics of radiation therapy,because it is the only method to estimate patient dose delivery fast forward and accurately represent estimated tumor location of the tumor with the possibility of estimating densities in the tissue surrounding the tumor to overcome dose calculation defects but radial estimated the *** the flaws associated with the systems and calculates the dose of your programs in all programs currently existing in the *** necessary,to the existence of a review of the accuracy of accounts and how to confirm the radiation dose to the patient *** A total of 35 cancer patients were considered for this study,with 245 field measurements made with low-and high-energy diode detectors for brain and prostate *** treatments for all patients were planned using Eclipse Treatment Planning System version *** Of the 105 field measurements made for the prostate cancer patients,16 included discrepancies outside the ±5% action *** the 145 measurements taken of the brain cases,there were four outside the ±5% action *** results indicated a higher degree of *** study revealed that,for the prostate measurements,the higher discrepancy in the doses for the particular fields(exceeding the action level) may have been due to the isocenter being very close to the jaws and multi-leaf collimator of the linear accelerator *** a result,scatter from the jaws and the multi-leaf collimator could have contributed to the high dose delivered to the diode;hence,a probable higher discrepancy of the dose in more brain cases due highest quality of VMAT technique and fixation *** A greater percentage of the observed discrepancies were well within the set tolerance ***,it is recommended that the positioning of the diode on the patient's skin and the angular sensitivity of the diodes be *** is also recommended that a m

关键词： diodes in vivo dosimetry radiotherapy dose verification

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Development of Accurate/Advanced Radiotherapy Treatment Planning and Quality Assurance System(ARTS)

Development of Accurate/Advanced Radiotherapy Treatment Plan...

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第十二届反应堆数值计算与粒子输运学术会议

作者：吴宜灿宋钢曹瑞芬吴爱东程梦云汤正道李贵景佳刘慧李佳兰海洋孟耀郑华庆金雏凤曾勤郑善良黄群英吴李君李国丽林辉陶声祥施常备 Institute of Plasma Physics Chinese Academy of Science

A prototype of accurate/advanced radiotherapy treatment planning and quality assurance system (ARTS) has been developed and key technical issues related to the improvement of the trcatment accuracy have been *** a brief introduction to the prototype of ARTS,the advanced development in key technical issues is presented,covering image data processing and human body modeling,fast and accurate hybrid dose calculation,multi-objective optimization of inverse planning,intelligent patient positioning,and dose verification.

关键词： radiotherapy treatment planning system modeling hybrid dose calculation inverse planning positioning dose verification

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