Dose Distribution Verifications of IMRT for NPC
Dose Distribution Verifications of IMRT for NPC作者机构:Cancer CenterUnion HospitalTongji Medical CollegeHuazhong University of Science and Technology
出 版 物:《Journal of Huazhong University of Science and Technology(Medical Sciences)》 (华中科技大学学报(医学英德文版))
年 卷 期:2009年第29卷第5期
页 面:673-676页
核心收录:
学科分类:1001[医学-基础医学(可授医学、理学学位)] 10[医学]
主 题:dose distribution dose verification intensity modulated radiation therapy
摘 要:In order to explore a dose distribution verification procedure of intensity modulated radiation therapy (IMRT) for nasopharyngeal carcinoma (NPC) and establish its evaluation criteria, we performed 35 two-dimensional (2D) patient-specific IMRT verifications over the year i006. The percent of pixels passing 7 and the normalized agreement test (NAT) index were mainly used to represent the agreement between the measured and computed dose distributions with three criteria (2%/2 mm, 3%/3 mm and 5%/3 mm) as recommended in the literature. The results were that all cases passed through verifications with three criteria except that the NAT index of one case was beyond the limitation, and the three tolerance levels of 2%/2mm, 3%/3 mm and 5%/3 mm produced similar clinical verification results but led to different percent of pixels passing Y and NAT index. Our data showed that the percent of pixels passing y and the NAT index were complementary to evaluate future IMRT verifications as two significant metrics. Due to the influence of the noise and the trait of the software, we considered an IMRT plan as acceptable in case of the percent ofpixels passing y 〉95% and the NAT index 〈5 with the 5%/3 mm criteria for IMRT patient-specific quality assurance (QA).