检索结果-南通市图书馆

Serum sodium concentration is significantly associated with the angiographic characteristics of coronary atherosclerosis

引用

Acta Pharmacologica Sinica 2007年第8期28卷 1136-1142页

作者： En-zhi JIA~2 Zhi-jian YANG Tie-bing ZHU Lian-sheng WANG Bo CHEN Ke-jiang CAO Jun HUANG Wen-zhu MA Department of Cardiovascular Medicine,First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China Department of Cardiovascular Medicine First Affiliated Hospital of Nanjing Medical University Nanjing China

Aim:To explore the relationship between serum sodium concentration and coro-nary ***:The study population consisted of 896 consecu-tive patients(684 males and 212 females)who underwent coronary angiographyfor suspected or known coronary *** and drinking *** anthropometric measurements,including body mass index,systolic blood pressure and diastolic blood pressure,and the serum measurements,including sodium,potassium,chlorine,lipids,blood glucose,urea,creatinine,anduric acid for every patient were *** severity of coronary atheroscle-rosis was defined by the Gensini score *** statistical methods,includingone-way ANOVA,Kruskal-Wallis test,Spearman correlation analysis,partial cor-relation analysis,multivariate stepwise linear regression analysis,and multinomiallogistic regression analysis were employed to explore the relationship betweenserum sodium concentration and the Gensini ***:The analysis of theKruskal-Wallis test indicated that the distribution of the Gensini score(P=0.000)differed among the groups according to serum sodium concentration,quartilevalues of which were used as cut-off *** Spearman correlation and partialcorrelation analysis controlling for gender,smoking status,and drinking statusindicated that the Gensini score significantly correlated with the sodium concen-tration(r=-0.241,P=0.000 for the Spearman correlation,r=-0.114,P=0.000 for thepartial correlation).The results from the multivariate stepwise linear regressionanalysis showed that the left ventricular ejection fraction(β=-0.228,P=0.000),age(β=0.137,P=0.010),glucose level(β=0.129,P=0.000),and sodium level(β=-0.106,P=0.004)were significantly and independently associated with the Gensini *** results of the multinomial logistic regression analysis suggested that thehyponatremia was the risk factor for the higher Gensini ***:Theserum sodium concentration was significantly and negatively ass

关键词： sodium coronary atherosclerosis Gensini score

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Relationship between leukocyte count and angiographical characteristics of coronary atherosclerosis

引用

Acta Pharmacologica Sinica 2005年第9期26卷 1057-1062页

作者： En-zhi JIA~(2,5) Zhi-jian YANG~2 Biao YUAN~3 Xiao-ling ZANG~4 Rong-hu WANG~4 Tie-bing ZHU~2 Lian-sheng WANG~2 Bo CHEN~2 Wen-zhu MA~22 Departments of Cardiovascular Medicine,3 Chest Surgery and4 Clinical Laboratory,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China Departments of Cardiovascular Medicine the First Affiliated Hospital of Nanjing Medical University Nanjing China Chest Surgery the First Affiliated Hospital of Nanjing Medical University Nanjing China Clinical Laboratory the First Affiliated Hospital of Nanjing Medical University Nanjing China

Aim:To explore the relationship between differential leucocyte count and coro-nary ***:The study population consisted of 507 consecu-tive patients(376 male and 131 female)who underwent coronary angiography forsuspected or known coronary *** patients’ smoking and drink-ing habits were investigated,and anthropometric measurements,serummeasurements,and hematological measurements were conducted for every *** severity of coronary atherosclerosis was defined by using Gensini’s ***-way ANOVA,Spearman’s correlation analysis,and multivariatestepwise linear regression analysis were employed to explore the relationshipbetween differential leucocyte count and coronary ***:One-way ANOVA indicated that the diastolic blood pressure,glucose,urea,creatinine,leukocyte count,neutrophil count,monocyte count,hemoglobin,and plateletcount differed among the groups according to Gensini’s score,the tertile valuesof which were used as cutoff ***’s correlation analysis suggestedthat Gensini’s score was significantly correlated with age,diastolic blood pressure,glucose,urea,creatinine,leukocyte count,neutrophil count,monocyte count,hemoglobin,and erythrocyte count,*** stepwise linearregression analysis show that neutrophil count(β=0.247,P=0.000),age(β=0.141,P=0.001),glucose(β=0.173,P=0.000),creatinine(β=0.088,P=0.063),hemoglobin(β=-0.168,P=0.013)and sex(men were coded as 1 and women were coded as 2;β=-0.121,P=0.012)were significantly independently associated with the Gensini’***:The independent association of neutrophil count with theangiographical characteristics of coronary atherosclerosis,as estimated byGensini’s score,strongly suggests that granulocytosis may play a role in thedevelopment of coronary atherosclerosis.

关键词： leukocyte count lymphocyte count monocyte count neutrophils coronary atherosclerosis Gensini’s score

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Correlation among obstructive sleep apnea syndrome,coronary atherosclerosis and coronary heart disease

引用

Chinese Medical Journal 2007年第18期120卷 1632-1634页

作者： LU Gan XU Zhuo-wen ZHANG Yu-lin YANG Zhi-jian ZHANG Xi-long YIN Kai-sheng Department of Pulmonary Medicine Gerontology ResearchInstitution of Jiangsu Province Nanjing 210024 China Department of Cardiology First Affiliated Hospital oi~ Nanjing Medical University Nanjing 210029 China Department of Respiratory Medicine First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China

Epidemiologic investigations have shown that the morbidity of obstructive sleep apnea syndrome （OSAS） among adults is 2%-4%, among the population aged 30 years and over is 4.63%, and among patients with hypertension or coronary atherosclerostic disease （CAD） is as high as 30%-50%.1 Many studies have indicated that OSAS may be closely associated with the development of CAD since increased incidence and mortality of CAD were found in OSAS patients. However, although it has been confirmed that OSAS is an independent risk factor for hypertension, its exact correlation with CAD has not been entirely elucidated. The aim of the present study was to explore the correlation between the degrees of OSAS and CAD with the application of coronary artery angiography （CAA）, Gensini scoring evaluation system, and other risk factors which may contribute to CAD.

关键词： obstructive sleep apnea syndrome coronary artery disease coronary atherosclerosis coronary artery angiography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relationship between high-sensitivity C-reactive protein level and angiographical characteristics of coronary atherosclerosis

引用

Chinese Medical Journal 2006年第4期119卷 319-323页

作者： JIA En-zhi YANG Zhi-jian YUAN Biao ZANG Xiao-ling WANG Rong-hu ZHU Tie-bing WANG Lian-sheng CHEN Bo CAO Ke-jiang HUANG Jun MA Wen-zhu Department of Cardiovascular Medicine First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China Department of Chest Surgery First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China Department of Clinical Laboratory First affiliated hospital of Nanjing Medical University Nanjing 210029 China

A role for inflammation has become well established over the past decade or more in theories describing the atherosclerotic disease process. From a pathological viewpoint, all stages, ie, initiation, growth, and complication of the atherosclerotic plaque, might be considered to be an inflammatory response to injury. Several prospective studies recently showed that plasma high sensitivity C-reactive protein （hsCRP） levels, which are one of the markers of systemic inflammation, are a powerful predictor of future myocardial infarction and cardiac death among apparently healthy individuals. However, the association between the plasma hsCRP levels and the extent of coronary stenosis in subjects remains controversial. Some studies previously demonstrated such associations, whereas other could not found. Gensini＇s score assigns a severity score for a stenosed vessel depending on the degree of luminal narrowing and the importance of its location.

关键词： C-reactive protein coronary atherosclerosis Gensini's score

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insights Into Evaluating the Total coronary atherosclerosis Burden

引用

Cardiology Discovery 2024年第3期4卷 221-230页

作者： Jinxing Liu Naqiang Lv Yingzhen Gu Xiaorong Han Yifan Li Xuze Lin Wei Zhang Aimin Dang Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China

The coronary plaque burden represents an essential tool for evaluating coronary blood flow and cardiovascular ***,the concept of“coronary plaque burden”does not accurately reflect the complex pathological progression of coronary artery *** this review,various aspects of the total coronary atherosclerosis burden are present,including its mechanics,geometrical characteristics,plaque morphology,coronary artery calcium deposition,and coronary inflammation,to provide a complete *** tools used to evaluate the coronary atherosclerosis burden are also assessed according to the most recent *** evidence is provided by our findings to advocate for a comprehensive use of the term“coronary atherosclerosis burden”.

关键词： coronary artery disease coronary plaque burden coronary atherosclerosis coronary artery calcium coronary inflammation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Expression characteristics of neutrophil and mononuclear-phagocyte related genes mRNA in the stable angina pectoris and acute myocardial infarction stages of coronary artery disease

引用

Journal of Geriatric Cardiology 2015年第3期12卷 279-286页

作者： Chuan-Rong LI Le-Min WANG Zhu GONG Jin-Fa JIANG Qiang-Lin DUAN Wen-Wen YAN Xiao-Hui LIU Department of Cardiology Tongji Hospital Tongji University School of Medicine Shanghai China

Objective To investigate expression differences of neutrophil and mononuclear phagocyte related gene mRNAs among acute myocardial infarction （AMI）, stable angina （SA） and control groups, and then discuss their expression characteristics in the stable angina pectoris （SAP） and AMI stages of coronary artery disease （CAD）. Methods Whole Human Genome Oligo Microarrays were applied to assess the differential expression characteristics of neutrophil and mononuclear phagocyte related mRNAs in patients with AMI （n = 20）, SA （n = 20） and controls （n = 20）. Results （1） Almost all colony-stimulating factors （CSF） and their receptors related mRNAs was up-regulated in AMI and SA groups compared with the control group, and the expression of granulocyte-macrophage colony stimulating factor receptor （GM-CSFR） and granulocyte colony stimulating factor receptor （G-CSFR） mRNAs in the AMI group was significantly up-regulated compared with the other two groups （P 〈 0.01）. （2） The expression of mRNAs related to monocyte chemoattractant protein-1 （MCP-1）, CCR2 （MCP-1 receptor） and CXCR2 （IL-8 receptor） was significantly up-regulated （P 〈 0.01） in AMI group compared with SA and control groups IL-8 mRNA expression in the AMI group was clearly higher than the controls （P 〈 0.05）. （3） All mRNAs expression related to opsonic re- ceptors （IgG FoR and C3bR/C4bR） was significantly up-regulated in AMI group compared with SA and control group （P 〈 0.01）, and the SA group showed an upward trend compared with controls. （4） Most pattern recognition receptor （PRR）-related mRNAs expression was up-regulated in AMI group compared with SA and control groups. Most toll-like receptor （TLR） mRNAs expression was significantly up-regulated （P 〈 0.01） than the SA and control groups, macrophage scavenger receptor （MSR） mRNA was significantly up-regulated in AMI group compared with the control group （P 〈 0.01）, and the SA group showed an upward trend compared with the controls. Conclusions The expression of most n

关键词： Acute myocardial infarction coronary atherosclerosis Mononuclear-macrophage Neutrophil

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intelligent H_(2)S release coating for regulating vascular remodeling

引用

Bioactive Materials 2021年第4期6卷 1040-1050页

作者： Bingyang Lu Xiao Han Ansha Zhao Dan Luo Manfred FMaitz Haohao Wang Ping Yang Nan Huang Key Laboratory of Advanced Technologies of Materials Ministry of EducationSouthwest Jiaotong UniversityChengdu610031China School of Materials Science and Engineering Southwest Jiaotong UniversityChengdu610031China Leibniz-Institute of Polymer Research Dresden Max Bergmann Center of Biomaterials DresdenHohe Strasse 601069DresdenGermany

coronary atherosclerotic lesions exhibit a low-pH chronic inflammatory *** to insufficient drug release control,drug-eluting stent intervention can lead to delayed endothelialization,advanced thrombosis,and unprecise *** this study,hyaluronic acid and chitosan were used to prepare pH-responsive self-assembling *** hydrogen sulfide(H2S)releasing aspirin derivative ACS14 was used as drug in the *** film regulates the release of the drug adjusted to the microenvironment of the lesion,and the drug balances the vascular function by releasing the regulating gas H2S,which comparably to NO promotes the self-healing capacity of blood *** releasing profiles of the films at different pH,and other biological effects on blood vessels were evaluated through blood compatibility,cellular,and implantation *** novel method of self-assembled films which H2S in an amount,which is adjusted to the condition of the lesion provides a new concept for the treatment of cardiovascular diseases.

关键词： pH responsive Layer-by-layer self-assembly film H_(2)S coronary atherosclerosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cardiac evaluation of liver transplant candidates

引用

World Journal of Gastroenterology 2008年第22期14卷 3445-3451页

作者： Mercedes Susan Mandell JoAnn Lindenfeld Mei-Yung Tsou Michael Zimmerman Department of Anesthesiology University of Colorado Health Sciences Center Aurora Colorado 80045 United States Department of Cardiology University of Colorado Health Sciences Center Aurora Colorado 80045 United States Department of Anesthesiology Taipei Veterans General Hospital and National Yang-Ming University School of MedicineTaipei Taiwan Department of Surgery University of Colorado Health Sciences Center Aurora Colorado 80045 United States

Physicians previously thought that heart disease was rare in patients with end stage liver disease. However, recent evidence shows that the prevalence of ischemic heart disease and cardiomyopathy is increased in transplant candidates compared to most other surgical candidates. Investigators estimate that up to 26% of all liver transplant candidates have at least one critical coronary artery stenosis and that at least half of these patients will die perioperatively of cardiac complications. Cardiomyopathy also occurs in greater frequency. While all patients with advanced cardiac disease have defects in cardiac performance, a larger than expected number of patients have classical findings of dilated, restrictive and hypertropic cardiomyopathy. This may explain why up to 56% of patients suffer from hypoxemia due to pulmonary edema following transplant surgery. There is considerable controversy on how to screen transplant candidates for the presence of heart disease. Questions focus upon, which patients should be screened and what tests should be used. This review examines screening strategies for transplant candidates and details the prognostic value of common tests used to identify ischemic heart disease. We also review the physiological consequences of cardiomyopathy in transplant candidates and explore the specific syndrome of "cirrhotic cardiomyopathy".

关键词： coronary artery disease coronary atherosclerosis Echocardiography Cirrhosis Cardiomyo pathy Cardiac electrophysiology liver transplantation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Congenital absence of the right coronary artery:A case report

引用

World Journal of Clinical Cases 2022年第34期10卷 12799-12803页

作者： Xiao-Yong Zhu Xin-Hu Tang Department of Cardiology Jiujiang University Affiliated HospitalJiujiang 332000Jiangxi ProvinceChina

BACKGROUND As a rare anomaly,congenital absence of the right coronary artery(RCA)occurs during the development of coronary *** with congenital absence of the RCA often show no clinical symptoms,and this disease is considered *** left coronary artery gives blood supply to the whole *** prevalence of congenital absence of the RCA is approximately 0.024%-0.066%.There are few cases reported as for this *** this work,a patient,with congenital absence of the RCA diagnosed by coronary angiography(CAG),was *** SUMMARY A 41-year-old man arrived at our hospital for treatment,due to the repeated palpitations for a duration of one *** the possibility of coronary heart disease,the patient underwent CAG that indicated the congenital absence of the ***,the patient refused to accept computed tomography coronary angiography(CTCA),to further confirm the congenital absence of the *** Single coronary artery is a rare type of coronary artery abnormality,which usually has no obvious clinical manifestations and is considered as a benign *** is the main means by which congenital absence of the RCA can be diagnosed,and the disease can also be further confirmed by CTCA.

关键词： Single coronary artery coronary atherosclerosis Absence of right coronary artery coronary angiography Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pathology of atherosclerotic coronary artery disease in the young Indian population

引用

Forensic Sciences Research 2019年第3期4卷 241-246页

作者： Pradeep Vaideeswar Shashank Tyagi Saranya Singaravel Department of Pathology(Cardiovascular&Thoracic Division) Seth GS Medical College&KEM HospitalMumbaiIndia Department of Forensic Medicine&Toxicology Seth GS Medical College&KEM HospitalMumbaiIndia

Atherosclerotic coronary artery disease (CAD) is of great concern in young adults because of its potential to cause great *** arena of cardiology has gained importance in South Asian countries,particularly India due to increased prevalence that is related to traditional risk factors,altered life styles and inherent risk *** this study,we sought to evaluate,at autopsy,the pathology of atherosclerotic CAD in young patients with ischemic heart disease (IHD).A 10-year retrospective autopsy-based study was carried out in a large tertiary-care centre and patients aged ≤45 years with IHD were *** of 545 autopsied cases of IHD,95 patients (17.4%) were *** these 95 patients,84 (88.4%) had IHD related to atherosclerotic CAD;the youngest patient was 18years *** there was sole involvement of left anterior descending artery and the presence of fibrous *** of the plaque morphology,the commonest complication was thrombosis produced by plaque erosion seen in 36.9% of *** coronary insufficiency was noted in 52 patients (61.9%),while healed infarctions were surprisingly noted in 28 patients (33.3%).Screening for IHD in the young population may help to improve prognosis by detecting subclinical disease,although more studies are necessary to establish reference limits for this young *** research must also focus on treatment concerns that are specific to young patients.

关键词： Forensic sciences forensic pathology ischemic heart disease coronary atherosclerosis young adults sudden cardiac death

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：