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Experimental Tibetan monkey domestication and its application for intraocular pressure measurement

International Journal of Ophthalmology(English edition) 2012年第3期5卷 277-280页

作者： Yong Yi, Xu-Yang Liu Institute of Laboratory Animals of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital Chengdu 610212 Sichuan Province China Shenzhen Eye Hospital Jinan University Shenzhen 518000 Guangdong Province China Ophthalmic Laboratories & Department of Ophthalmology West China Hospital Sichuan University Chengdu 610041 Sichuan Province China

AIM: To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque. METHODS: The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training. RESULTS: Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVete (R) rebound tonometer without sedation or anesthesia and their IOP values were similar to other primates. CONCLUSION: Human-cultivated Thibetan monkeys are tamable, and can be used for biomedical research such as ophthalmic research without anesthesia.

关键词： Macaca thibetana domestication conscious intraocular pressure measurement

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Experimental Tibetan monkey domestication and its application for intraocular pressure measurement

Experimental Tibetan monkey domestication and its applicatio...

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第十届中国实验动物科学年会

作者： Yong Yi Tao Zeng Liang Zhou Su-Ping Cai Yan Yin Yun Wang Xu Cao Yue-Zhong Xu Hong-Xing Wang Xu-Yang Liu Institute of Laboratory Animals of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital Shenzhen Eye Hospital Jinan University Ophthalmic Laboratories & Department of Ophthalmology West China HospitalSichuan University

AIM:To train Tibetan monkey(Macaca thibetana) for intraocular pressure(IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque. METHODS:The training was based on award-conditioned *** stimulation and human-animal interaction were used in this training. RESULTS:Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVetrebound tonometer without sedation or anesthesia and their IOP values were similar to other primates. CONCLUSION:Human-cultivated Thibetan monkeys are tamable,and can be used for biomedical research such as ophthalmic research without anesthesia.

关键词： Macaca thibetana domestication conscious intraocular pressure measurement

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