Experimental Tibetan monkey domestication and its application for intraocular pressure measurement

作     者：Yong Yi, Xu-Yang Liu 

作者机构：Institute of Laboratory Animals of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital Chengdu 610212 Sichuan Province China Shenzhen Eye Hospital Jinan University Shenzhen 518000 Guangdong Province China Ophthalmic Laboratories & Department of Ophthalmology West China Hospital Sichuan University Chengdu 610041 Sichuan Province China 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2012年第5卷第3期

页      面：277-280页

核心收录：

学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：National Natural Science Foundation of China (No.81170851) Capital Project of the Transfer of Scientific and Technological Achievements in Research Institutes of Sichuan Province, China (2009 Chuan fiscal teach No.36) Sichuan Provincial Health Department Scientific Research Project, China (No.100474) 

主　　题：Macaca thibetana domestication conscious intraocular pressure measurement 

摘      要：AIM: To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque. METHODS: The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training. RESULTS: Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVete (R) rebound tonometer without sedation or anesthesia and their IOP values were similar to other primates. CONCLUSION: Human-cultivated Thibetan monkeys are tamable, and can be used for biomedical research such as ophthalmic research without anesthesia.