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Effect of early stepwise cardiopulmonary rehabilitation on function and quality of life in sepsis patients

World Journal of Clinical Cases 2024年第4期12卷 729-736页

作者： Ming-Hui Zheng Wen-Jun Liu Juan Yang Division of Cardiovascular First Ward Departments of Internal Medicine Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430077Hubei ProvinceChina Department of Respiratory Medicine PuRen Hospital Affiliated to Wuhan University of Science and Technology/Respiratory MedicineWuhan 430000Hubei ProvinceChina Department of Cardiology Huanggang Central HospitalHuanggang 438000Hubei ProvinceChina

BACKGROUND Sepsis,as a non-limiting host infection disease,can be accompanied by serious complications such as organ failure,which seriously threatens patient quality of *** To investigate the effect of early stepwise cardiopulmonary rehabilitation on cardiopulmonary function and quality of life in patients evacuated from mechanical ventilation with *** A total of 80 patients with sepsis who were hospitalized in our hospital from January 2021 to January 2022 were selected and divided into the observation group(n=40)and the control group(n=40)according to the random number table *** observation group was treated with early stepwise cardiopulmonary rehabilitation,and the control group was treated with a conventional treatment *** function indexes(central venous pressure,cardiac troponin I,B-type brain natriuretic peptide),lung function indicators(diaphragmatic mobility,changes in central venous oxygen saturation,oxygenation index),and quality of life(Quality of Life Evaluation Scale)were compared between the two groups after *** After treatment,the central venous pressure,diaphragm mobility,central venous oxygen saturation,oxygenation index,and Quality of Life Evaluation Scale scores in the observation group were higher than those in the control group,and the differences were statistically significant(Pcardiopulmonary rehabilitation can effectively enhance cardiac and pulmonary function and improve the quality of life in patients evacuated from mechanical ventilation with sepsis.

关键词： Stepwise cardiopulmonary rehabilitation Sepsis Evacuation of mechanical ventilation cardiopulmonary function Quality of life

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Protective effects of hypovolemic hypotension preconditioning on cardiopulmonary function after myocardium ischemia/reperfusion injury

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Chinese Journal of Traumatology 2004年第6期7卷 368-371页

作者：陈雪君王昕夏中元罗涛涂仲凡 Department of Anesthesiology Renmin Hospital Wuhan University Wuhan 430060 China Department of Cardiac Surgery Renmin Hospital Wuhan University Wuhan 430060 China

Objective: To identify the protective effects of hypovolemic hypotension preconditioning on cardiopulmonary function after myocardial ischemia/reperfusion injury and to explore the possible ***: Twenty-four male white rabbits were randomly assigned to two groups. In the control group, ischemia/reperfusion animals(Group I/R, n=10) were subjected to thirty-minute occlusion of left anterior descending coronary artery and two-hour reperfusion. Animals in hypovolemic hypotension preconditioning group (Group HHP, n=14) experienced brief systemic ischemia preconditioning through blood withdrawl to lower blood pressure to 40%-50% of the baseline before myocardial ischemia/reperfusion. Hemodynamic parameters were recorded. Blood sample was taken to measure superoxide dismutase (SOD), malondialdehyde (MDA) and nitrogen monoxide (NO) changes with blood gas analysis. Myocardium specimens were sampled to examine apoptosis-related gene interleukin-1 beta converting enzyme (ICE) mRNA. Results: Cardiac mechanical function and lung gas exchange remained stable in Group HHP with a significant increase in NO level; while in Group I/R without preconditioning, cardiopulmonary dysfunction was present after 2 h reperfusion associated with a significant reduction in NO formation and an increase in MDA (Pcardiopulmonary function and increases NO formation and the protective benefit associated with hypovolemic hypotension preconditioning of the heart may be regulated through NO mediated mechanism.

关键词： Hypotension Ischemic preconditioning, myocardial Reperfusion injury cardiopulmonary function

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Impact of 60 Days of 6° Head Down Bed Rest on cardiopulmonary function,and the Effects of Taikong Yangxin Prescription(太空养心方) as A Countermeasure

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Chinese Journal of Integrative Medicine 2014年第9期20卷 654-660页

作者：石宏志李勇枝唐志忠仲崇发范全春高建义刘军莲米涛赵爽李莹辉 State Key Laboratory of Space Medicine Fundamentals and Application China Astronaut Research and Training Center

Objective： To study the changes in cardiopulmonary function induced by mid/long-term simulated microgravity with 6^° head down bed rest （HDBR）, and the effects of Taikong Yangxin Prescription （太空养心方, TYP） as a countermeasure. Methods： Fourteen healthy male volunteers were randomly divided into a control group and a Chinese medicine （CM） group （7 in each group） by a random digital table based on their body weight. Both groups underwent6^° HDBR for 60 days. Subjects in the CM group received daily TYP pills and subjects in the control group received daily placebo pills. Cardiac systolic and pumping functions were measured by echocardiography before HDBR; on days 20, 42, and 57 of HDBR; and on day 3 of recovery after HDBR （R＋3）. cardiopulmonary functional reserve and exercise capacity were evaluated before HDBR, on day 29, and on day R＋3 by exercise testing. Results： The heart rate （HR） increased gradually during HDBR. The HR was significantly higher on day 57 than before HDBR in the control group （P〈0.05）, but did not increase significantly in the CM group. The stroke volume/stroke volume index, ejection fraction, and left ventricular fractional shortening tended to decrease over time in the control group, but not in the CM group. These parameters were significantly higher in the CM group than in the control group on day 42 （P〈0.05 or P〈0.01）. Exercise testing showed that maximum 02 consumption （VO2max）, metabolic equivalents, relative 02 consumption （VO2）, 02 pulse, and exercise duration were significantly lower on day 29 than before HDBR in the control group, but not in the CM group. Conclusions： Sixty days of 6^° HDBR induced a reduction in cardiac systolic and pumping functions, and reduced cardiopulmonary functional reserve and exercise capacity. Administration of TYP significantly improved cardiac systolic and pumping functions, and maintained cardiopulmonary functional reserve and exercise capacity.

关键词： 6^°head down bed rest weightlessness simulation cardiopulmonary function Taikong Yangxin Prescription

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Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure

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World Journal of Clinical Cases 2024年第17期12卷 3027-3034页

作者： Ji-Jie Xu Jian Dai Qi-Hai Xie Pei-Chao Du Cha Li Hua Zhou Department of Cardiology&Cardiovascular Research Institute Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western MedicineShanghai 201999China

BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically *** optimization of treatments for this disease needs to be explored and *** To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function(CPF)and *** In total,160 patients with CHF admitted between June 2022 and June 2023 were selected,including 75 receiving perindopril(control group)and 85 receiving Luhong Formula(research group).We conducted comparative analyses on the curative effects of traditional Chinese medicine(TCM)syndromes and cardiac function,CPF[oxygen consumption at the anaerobic threshold(VO2 AT)and at peak exercise(peak VO2)],echocardiographic indexes[left atrial volume index(LAVI),left ventricular muscle mass index(LVMI),left ventricular ejection fraction(LVEF)],and prognosis[major adverse cardiovascular events(MACEs)at 6 months follow-up].RESULTS The research group showed markedly higher curative effects of TCM syndromes and cardiac function than the control *** addition,post-treatment VO2 AT,peak VO2,LVMI and LVEF in the research group were significantly higher,whereas LAVI was significantly lower,than those of the control ***,fewer patients in the research group developed MACEs at the 6-month *** Luhong Formula is more therapeutically effective than perindopril for the cardiac rehabilitation of patients with CHF,specifically in enhancing CPF and prognosis.

关键词： Luhong formula Chronic heart failure cardiopulmonary function Cardiac rehabilitation Prognosis

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Research and Practice of cardiopulmonary Rehabilitation Training Programs

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World Journal of Cardiovascular Diseases 2024年第9期14卷 557-566页

作者： Na Yan Maiding He Jinyue Jiang Juan Luo Ping Zhan Xichan Wang Xia Gao Jianzhu Wang Na Yin Fang Ye Jinghua Yu Shiying Zhang Rehabilitation Medicine Qujing No. 1 Hospital Qujing China Rehabilitation Medicine Qujing Multi-Rehabilitation Hospital Qujing China

In today’s society, the incidence of cardiopulmonary diseases is increasing annually, seriously affecting patients’ quality of life. Therefore, developing a scientific and effective rehabilitation training program is of great significance. This study first analyzes the theoretical basis of cardiopulmonary rehabilitation training, including the effects of aerobic exercise, interval training, and strength training on cardiopulmonary function. Based on this, a comprehensive rehabilitation training program is designed, which includes personalized training plans, comprehensive interventions, multidisciplinary collaboration, patient education, and regular follow-up visits. The cardiopulmonary rehabilitation training plan developed in this study has certain scientific practicability, which provides a theoretical basis for cardiopulmonary rehabilitation training, and also provides a reference for medical institutions, rehabilitation centers and communities, which is helpful for promotion and application to a wider range of patients with cardiopulmonary diseases.

关键词： cardiopulmonary function Rehabilitation Training Program Aerobic Exercise Interval Training

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Effects of chest compressions on cardiorespiratory function in a non-arrested porcine model

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Chinese Medical Journal 2013年第12期126卷 2348-2353页

作者： CONG Lu-hong LI Chun-sheng GUO Zhi-jun WANG Shuo WU Jun-yuan YUAN Wei Department of Emergency Medicine Beijing Chaoyang Hospital Capital Medical University Beijing 100020 China

Background The effects of chest compressions to hemodynamic and respiratory parameters during hands-only cardiopulmonary resuscitation （CPR） in a non-arrested patient who suddenly collapses are *** this research,we investigated the effects of chest compressions in a non-arrested porcine *** Fourteen male domestic pigs were randomized into sham control group （SHAM group,only anesthetized and instrumented without chest compression,n=6） or chest compression group （CC group,2 minutes of chest compressions,n=8）.Continuous hemodynamic parameters,dynamic lung compliance （Cdyn）,and blood gas analysis outcomes were *** levels of catecholamine were measured at baseline and 2 minutes,30 minutes,4 hours,and 24 hours after chest *** computed tomography （CT） was performed at 30 minutes and 24 *** histopathology evaluation was *** After two minutes of chest compressions in the CC group,heart rate and extravascular lung water increased significantly; mean arterial pressure,stroke volume,and global ejection fraction significantly *** significantly decreased to valley levels at 30 minutes and slowly *** with the baseline,serum levels of catecholamine significantly increased at 2 minutes and rapidly decreased 24 hours *** 30 minutes after chest compressions,chest CT showed local exudation,which was absorbed 24 hours *** This research showed that 2 minutes of chest compressions causes various heart and lung tissue damage in the normal a normal porcine *** also impacts the hemodynamic and Cdyn.

关键词： chest compression lung contusion cardiopulmonary function non-arrested

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A Study of Real-time Peak Oxygen Consumption and Six-minute Walk Test

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South China Journal of Cardiology 2007年第4期8卷 179-182页

作者： Guolin Zhang Lan Guo He Li Jingzhuang Mai Zhi Liu Sixian Huang Guangdong Cardiovascular Institute Guangdong Provincial People＇s Hospital Guangzhou 510080 China

Objectives To assess the relationship between peak oxygen consumption （PVO2） and the ambulation distance in six-minute walk test （6MWT）among the healthy subjects. Methods The 51 healthy subjects were recruited for the six-minute walk test. Data of pulmonary gas exchange breath by breath, such as VO2 , VCO2 were real-time measured with wireless remote sensing K4B2, so to study the relationship between peak oxygen uptake and the ambulation distance. Results It was noticed that there was a positive linear correlation between the ambulation distance and PVO2 （ r =0. 619, P 〈0. 001 ） in six-minute walk test. The regression equation was set up （ VO2/kg =0. 05D -6. 331, P 〈 0. 001 ）. PVO2 〉 PVCO2 ,R 〈 1 were found,which suggested that 6MWT was a test below anaerobic threshold. Conclusions There was a closely positive linear correlation between the ambulation distance and PVO2, which is safety, convenient and valuable for the evaluation of cardiopulmonary function and the treatment of cardiopulmonary rehabilitation.

关键词： six-minute walk test oxygen consumption(PVO2) cardiopulmonary function

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Cardiac exercise rehabilitation for heart failure:a review of the literature

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TMR Clinical Research 2021年第2期4卷 1-12页

作者： Yu Liu xian-Liang Wang Ying-Fei Bi Ya-Wen Cao Shuai Wang Ya-Zhu Hou Zhi-Qiang Zhao Shan-Shan Lin Zhe Wang Jing-Yuan Mao Cardiovascular Department First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjinChina

The most common symptom of patients with heart failure is reduced exercise tolerance,as indicated by decreased peak oxygen uptake(VO2peak),which is associated with both reduced quality of life and *** rehabilitation is a safe and effective treatment for clinically stable patients with heart failure,and is associated with improvements in cardiopulmonary function,muscle strength,physical functional performance,and quality of ***,cardiac rehabilitation is associated with a reduction in heart failure hospitalization and *** evidence of these benefits,cardiac rehabilitation referral and compliance among patients with heart failure remains *** this review,we discuss exercise and training program selection for patients with heart failure,including optimal exercise training intensity,and a summary of recent literature on the use of cardiac rehabilitation for patients with heart failure.

关键词： Cardiac rehabilitation Heart failure Exercise training Quality of life cardiopulmonary function

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中小学生身体形态、心肺功能与学业成绩的关系

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体育 2016年第12期

作者：梁哲张羽

本文利用西部某地区大样本学生数据，根据《国家学生体质健康标准》与《国家学生体质健康标准(2014年修订)》测试结果对比同一批学生的体质特点，通过描述统计、构建随机截距广义最小二乘法回归分析模型、引入交互项等数理统计方法，分... 详细信息

本文利用西部某地区大样本学生数据，根据《国家学生体质健康标准》与《国家学生体质健康标准(2014年修订)》测试结果对比同一批学生的体质特点，通过描述统计、构建随机截距广义最小二乘法回归分析模型、引入交互项等数理统计方法，分析身体形态、心肺功能与学业成绩的关系，进而对我国学校体育工作提出建议。结果表明：1)在新标准下，同一批学生的偏瘦现象大幅减少，高中学生肥胖问题有所凸显；中小学生普遍存在明显的肺活量不足；2)从体质指标与学业成绩的关系看，肺活量不达标的学生成绩较差，尤其是女生。心肺功能可能是影响学业表现的关键因素。因此，新标准将肺活量设为必测项目彰显了心肺功能监测的重要意义，指引着“多维健康、全面发展”的育人方向，通过学校重视、家庭支持以及社区开放等方面合力改善青少年体质健康刻不容缓。

关键词：中小学生身体形态心肺功能体质学业成绩国家标准 students physical shape cardiopulmonary function academic scores physical fitness national guideline

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