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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 956-961页

作者： Haseena Banu Hedayathullah Khan Kaladevi Siddhi Vinayagam Shanthi Palanivelu Sachdanandam Panchanadham Department of Medical Biochemistry DR.A.L.M.P-G.I.B.M.S.University of MadrasTaramani CampusChennai-600113India

Objective:To explore the protective effect of the drug Semecarpus anacardium(***) on altered glucose metabolism in diabetic ***:Type 2 diabetes mellitus was induced by feeding rats with high fat diet followed by single intraperitoneal injection of streptozotocin (STZ)(35 mg/kg b.w.).Seven days after STZ induction,diabetic rats received nut milk extract of *** *** milk extract orally at a dosage of 200 mg/kg daily for 4 *** effect of nut milk extract of *** on blood glucose,plasma insulin,glucose metabolising enzymes and GSK were ***:Treatment with SA extract showed a significant reduction in blood glucose levels and increase in plasma insulin levels and also increase in HOMA-βand decrease in HOMA -*** drug significantly increased the activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase activity and increased the glycogen content in liver of diabetic rats while reducing the activities of gluconeogenic *** drug also effectively ameliorated the alterations in GSK-3 mRNA ***:Overall,the present study demonstrates the possible mechanism of glucose regulation of *** suggestive of its therapeutic potential for the management of diabetes mellitus.

关键词： Semecarpus anacardium Streptozotocin Carbohydrate metabolism Insulin signalling

Phytochemical and Antifungal Activity of Leaf Extracts of Prosopis africana and anacardium occidentale against Macrophomina Root Rot of Sesamum indicum L. in Benue State, Central Nigeria

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Journal of Geoscience and Environment Protection 2018年第7期6卷 66-76页

作者： Matthew Elaigwu Hyacinth Ocheigwu Apeh Oluma Amana Onekutu Department of Integrated Science College of Education Oju Benue State Nigeria Department of Biological Sciences University of Agriculture Makurdi Benue State Nigeria

This study investigated the antifungal activity of leaf extracts of Prosopis africana and anacardium occidentale against Macrophomina phaseolina, the causal agent of root rot of Sesamum indicum L. Phytochemical analysis of the two plants showed the presence of alkaloids, saponins, tannins, flavonoids and anthraquinones in petroleum ether, ethyl acetate, methanol and water extracts. The effectiveness of the two medicinal plants viz: P. africana and A. occidentale was tested against the causative agent of root rot of Sesamum indicum L. The effect of plant leaf extracts on mycelia growth of the test organism shows that both P. africana and A. anacardium reduced the mycelia growth significantly as compared to the control (plate, 2, 3, 4). The antifungal property of P. africana and A. occidentale makes these plants of potential interest for the control of the fungi Macrophomina phaseolina.

关键词： Phytochemical Antifungal Screening Prosopis africana anacardium occidentale Leaf Extracts Macrophomina Phaseolina (Tassi) Goid

Radical Scavenging and Antioxidant Potential of Nuts and Leaves Extracts of <i>Semecarpus anacardium</i>(L.)

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American Journal of Plant Sciences 2013年第8期4卷 1679-1683页

作者： Nachiketa Barman Archna Sharma Ashwani Kumar Department of Botany Vedic Girls P. G. College University of Rajasthan Jaipur India Laboratory of Bioactive Compounds and Algal Biotechnology Department of Botany University of Rajasthan Jaipur India.

In the present investigation, antioxidant activity of the crude extracts from nuts and leaves of S. anacardium was carried out. The antioxidant potential of various extracts (ethanol, acetone and aqueous) of S. anacardium was determined by using DPPH assay, ABTS assay and metal chelating activity assay. Among the extracts the ethanol extract of nut showed significant scavenging activity (DPPH-88.73 ± 2.26;ABTS assay-81.65 ± 1.57 and metal chelating activity-72.37 ± 2.26) compared with antioxidant controls, ascorbic acid and BHA respectively. The findings of the present investigation suggest that the S. anacardium extracts can prove to be a potent source of biologically active compounds that can be further subjected to isolation of therapeutic antioxidant agents.

关键词： Semecarpus anacardium Anacardiaceae Antioxidant Activity

Ethanolic extract of cashew apple inhibits lipid metabolism and ameliorates obesity in atherogenic diet-induced obese rats

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Asian Pacific Journal of Tropical Biomedicine 2019年第10期9卷 405-414页

作者： Thatiparthi Jhansyrani Dodoala Sujatha Koganti Bharathi KVSRG Prasad Department of Pharmacology Institute of Pharmaceutical TechnologySri Padmavati Mahila VisvavidyalayamTirupati-517502Andhra PradeshIndia

Objective:To evaluate the anti-obesity activity of ethanolic extract of cashew apple using various in vitro and in vivo ***:Phytochemical screening was carried out in ethanolic extract of cashew apple,followed by quantification of phenol and *** potential was evaluated using 2,2-diphenyl-1-picrylhydrazyl and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)scavenging *** inhibitory effect of ethanolic extract of cashew apple on atic lipase was also *** addition,anti-obesity activity was determα-amylase and pancreined in two in vivo models,lipid emulsion model and atherogenic diet-induced obese rat *** of postprandial plasma triglycerides were assessed in lipid emulsion model,whereas serum lipid profile,in vivo antioxidants and histopathological studies of the carotid artery and liver were performed in an atherogenic diet-induced obese ***:Phytochemical screening revealed the presence of carbohydrates,alkaloids,polyphenols,terpenoids,and *** in vitro assays showed inhibition of *** extract of cashew appα-amylase and pancreatic lipase and strong antioxidant ple showed significant and timedependent inhibitory activity on postprandial triglycerides after administration of lipid emulsion for 5 *** extract of cashew apple at 200 and 400 mg/kg on day 60 showed a significant reduction in body weight,body mass index and atherogenic index,whereas lipid profile and liver function marker levels in the serum were decreased in a dose-dependent manner at time intervals(day 0,20,40,and 60)compared to the atherogenic diet-induced obese *** observations showed reduced non-alcoholic fatty liver deposits and decreased atherosclerotic fatty streak plaques(carotid artery)after treatment with ethanolic extract of cashew ***:Ethanolic extract of cashew apple ameliorates obesity,which may be partly mediated by its delayed absorption of cholesterol and carbohydrates

关键词： anacardium occidentale Atherogenic diet Lipid emulsion Lipid profile Obesity