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Association of Protein Energy wasting with Income in CKD Stage 3 Patients

World Journal of Engineering and Technology 2015年第3期3卷 45-51页

作者： Anita Saxena Amit Gupta Department of Nephrology Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow India

Protein energy wasting (PEW) is a major challenge in CKD. Objective: To assess PEW in predialysis patients on their first visit to a nephrologist. Methods: Three day dietary intake of 484 CKD stage 3 patients was taken. Appetite was assessed with ADAT. Patients were divided into groups based on appetite and BMI. Results: Male and female parameters are serum albumin 3.7 ± 0.84/3.68.8 ± 0.81 g/dL, total protein 7.02 ± 1.27/6.94 ± 1.26 g/dL, creatinine 4.68 ± 4.19/3.74 ± 3.36 mg% creatinine clearance 33.22 ± 30.48/37.55 ± 33.87 ml/minute, BMI 22.60 ± 4.29/23.43 ± 4.77kg/m2 energy/kg 16.97 ± 0.65/16.8 ± 0.64, protein g/kg 0.65 ± 0.28/0.64 ± 0.30, carbohydrate g/kg 2.98 ± 1.54/2.98 ± 0.1.36, fat g/kg 2.98 ± 0.23/2.79 ± 0.22, respectively. As appetite decreased, dietary protein and energy intake decreased significantly. Appetite in males and females: Average 14.46%, 4.13%, poor 9.7%, 18.18%, anorexic 13.2%, 7.4%. Income had strong correlation with BMI (p 0.000), dietary protein (p 0.000), energy (p 0.000) and carbohydrate (p 0.000). Appetite correlated with creatinine (p 0.019), dietary energy, protein, carbohydrate and fat (p 0.000) intake. BMI correlated (p 0.000) with fat, carbohydrate, energy and creatinine clearance. ANOVA showed significant difference within and between appetite groups in energy, protein, fat, carbohydrate, creatinine clearance (p 0.000) and serum albumin (p 0.025). There was significant difference in protein (p 0.026), energy intake (p 0.000) and creatinine clearance (p 0.038) within and between BMI groups. Based on income, there was significant difference among groups in BMI (p 0.000), energy (p 0.019), protein (p 0.031) and albumin (0.001).

关键词： Protein Energy wasting Appetite Income BMI Chronic Kidney Disease

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Geographic Information Technologies for the Study of Mass wasting Hazards

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International Journal of Geosciences 2014年第5期5卷 519-526页

作者： Henry Pacheco Carlos Suárez Universidad Pedagógica Experimental Libertador Instituto Pedagógico de Caracas Departamento de Ciencias de La Tierra. Centro de Investigación “Estudios del Medio Físico Venezolano” Venezuela

The purpose of the research was to obtain the mass wasting hazard map for the state of Vargas, central coast of Venezuela, using GIS technology. The work was developed through the heuristic method with the generation of thematic digital maps, univariate statistical treatment, weighting of each variable and quantifying the relationship of each parameter unit regarding mass wasting processes. The algorithm designed to perform map algebra was designed using the variables: surface geology, slope, slope orientation, terrain curvature, moisture topographic index, power index surface flow rate and capacity sediment transport and the rate normalized difference vegetation. The results show a distribution of landslide hazard with the highest values in the west central part of Vargas state, where the dominant lithology is incompetent, and combined with topographic elements, determining high instability, meanwhile the lower hazard areas were found in specific areas such as the middle watershed areas east of the state. The calibration of this model shows a reliability of 80%, so it is highly advisable to use the information generated in this work by governmental and non-governmental organizations in the planning, management and use of land.

关键词： Mass wasting Hazards GIS Vargas State Venezuela

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Hyponatremia during a Severe Pneumococcal Meningitis with Renal Salt wasting: A Cerebral Salt wasting Syndrome?

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Open Journal of Nephrology 2011年第1期1卷 1-4页

作者： Jean-Philippe Delabre Stephane Pommet Laurent Amigues Olivier Jonquet Kada Klouche 不详

Background: The existence and prevalence of cerebral salt wasting and its differentiation from syndrome of inappropriate antidiuretic hormone have been controversial. This controversy stems from overlapping clinical and laboratory findings and an inability to assess the volume status of these patients. Objectives:To present a case of a cerebral salt wasting syndrome secondary to a bacterial mengitis and to emphasize the difficulty to assess the diagnosis. Case report: A 51-year-old male admitted to the ICU for a severe bacterial meningitis who developed, four days later, hyponatremia associated with hypovolemia due to a renal salt wasting. Clinical and biological parameters were collected;electrolytes balances and salt clearances were calculated to best investigate this hydroelectrolytic disorder. Patient's volume status and improvement after fluid and sodium replacement highly suggests the diagnosis of a cerebral salt wasting syndrome. Conclusion: A thorough analysis of this case showed that occurrence of hyponatremia and renal salt wasting after brain agression is not univocal underlying the fact that the diagnosis of cerebral salt wasting should be assessed only after a careful examination of the different determinants of the hydroelectrolytical balance.

关键词： Bacterial Meningitis Cerebral Salt wasting Hyponatremia Natriuresis

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Impact of muscle wasting on survival in patients with liver cirrhosis

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World Journal of Gastroenterology 2015年第24期21卷 7357-7361页

作者： Maria Kalafateli Christos Konstantakis Konstantinos Thomopoulos Christos Triantos Department of Gastroenterology University Hospital of Patras

Muscle wasting is defined as the progressive and generalized loss of muscle mass. Muscle depletion is a common feature of chronic liver disease foundin approximately 40% of patients with cirrhosis. Its etiology is multifactorial subsequent to liver failure and its prevalence increases along with disease severity. Cross-sectional analytic morphometry using computed tomography(CT) scan or magnetic resonance imaging are considered by consensus the gold standards to assess muscle size in cirrhosis for research purposes because they are not biased by fluid accumulation. Several studies have assessed the impact of muscle wasting on overall survival of patients in the waiting list for liver transplantation and there is a general agreement that decreased muscle size assessed by CT scan is an independent predictor for mortality in cirrhosis. It has been proposed that the addition of cross-sectional muscle area into the Model for End-stage Liver Disease can increase its prognostic performance. Nevertheless, the use of CT scan in assessing muscle size is inappropriate for routine clinical practice and an alternative cost-effective, easy to use and accurate tool should be developed. In conclusion, muscle wasting has a detrimental impact on survival of patients with cirrhosis and, thus, it remains to be elucidated if nutritional interventions and exercise could improve muscle wasting and, subsequently, survival in this setting.

关键词： Cirrhosis Sarcopenia Malnutrition Survival Muscle wasting

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Prolonged coexistent central diabetes insipidus and cerebral salt wasting syndrome following neurosurgery

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Open Journal of Pediatrics 2013年第2期3卷 74-77页

作者： D. López de Lara B. Joyanes A. Llaneza O. Pérez B. Llorente I. Runkle Department of Endocrinology Hospital Clínico San Carlos Madrid Spain Department of Pediatrics Hospital Clínico San Carlos Madrid Spain

The coexistence of different water homeostasis abnormalities following neurosurgery represents a diagnostic and therapeutic challenge for intensive care units. This paper reports the case of a 13 year-old boy who underwent surgery for a suprasellar tumour and, immediately after surgery, developed a cerebral abscess, persistent diabetes insipidus (DI) as well as cerebral salt wasting syndrome (CSWS). The early onset of CSWS following DI has been associated with a poor prognosis and increased mortality. In cases in which these abnormalities coexist, the increased polyuria secondary to the rise in natriuresis associated with CSWS might be erroneously interpreted as a sign of poor control of the DI, thereby leading to therapeutic mistakes. Treatment basically consists of restoring electrolytes and the joint administration of desmopressin and fludrocortisone.

关键词： Electrolyte Disorder Diabetes Insipidus Cerebral Salt wasting Syndrome Neurosurgery

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Cyberloafing:The line between rejuvenating and wasting time

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数理天地（高中版） 2020年第4期 48-49页

Research shows that workers drift from their contracted tasks to personal email,social networks and the far corners of the internet for anything between a few hours a week to a few hours a *** out of 10people admit th... 详细信息

关键词： Cyberloafing:The line between rejuvenating and wasting time

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Muscle wasting in rheumatoid arthritis:The role of oxidative stress

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World Journal of Rheumatology 2014年第3期4卷 44-53页

作者： Antonios Stavropoulos-Kalinoglou Charikleia Deli George D Kitas Athanasios Z Jamurtas Department of Sport and Exercise Science University of Thessaly42100 TrikalaGreece Department of Rheumatology Dudley Group NHS Foundation TrustRussell’s Hall HospitalDudleyWest Midlands DY1 2HQUnited Kingdom Arthritis Research UK Epidemiology Unit University of ManchesterManchester M13 9PTUnited Kingdom Institute of Human Performance and Rehabilitation Centre for Research and Technology Thessaly42100 TrikalaGreece

Rheumatoid arthritis(RA), the commonest inflammatory arthritis, is a debilitating disease leading to functional and social disability. In addition to the joints, RA affects several other tissues of the body including the muscle. RA patients have significantly less muscle mass compared to the general population. Several theories have been proposed to explain this. High grade inflammation, a central component in the pathophysiology of the disease, has long been proposed as the key driver of muscle wasting. More recent findings however, indicate that inflammation on its own cannot fully explain the high prevalence of muscle wasting in RA. Thus, thecontribution of other potential confounders, such as nutrition and physical activity, has also been studied. Results indicate that they play a significant role in muscle wasting in RA, but again neither of these factors seems to be able to fully explain the condition. Oxidative stress is one of the major mechanisms thought to contribute to the development and progression of RA but its potential contribution to muscle wasting in these patients has received limited attention. Oxidative stress has been shown to promote muscle wasting in healthy populations and people with several chronic conditions. Moreover, all of the aforementioned potential contributors to muscle wasting in RA(i.e., inflammation, nutrition, and physical activity) may promote pro- or antioxidative mechanisms. This review aims to highlight the importance of oxidative stress as a driving mechanism for muscle wasting in RA and discusses potential interventions that may promote muscle regeneration via reduction in oxidative stress.

关键词： Rheumatoid arthritis Oxidative stress Muscle wasting Inflammation Cytokines Exercise

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狨猴wasting综合征

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实验动物与比较医学 1984年第3期 149-149页

作者： Martin L.Morin 殷世申

哺乳动物有时会莫名其妙地体重减轻或“消瘦下去”,这就给有关人员提出了一些令人迷惑的问题。人们发现,在大多数情况下,该问题与营养不良、慢性寄生虫病、食物中的有害物质、细菌感染或其他因素有关,但有些病例尚无法确诊。然而,狨猴... 详细信息

哺乳动物有时会莫名其妙地体重减轻或“消瘦下去”,这就给有关人员提出了一些令人迷惑的问题。人们发现,在大多数情况下,该问题与营养不良、慢性寄生虫病、食物中的有害物质、细菌感染或其他因素有关,但有些病例尚无法确诊。然而,狨猴的消瘦问题引起了人们特别的关注。一九七八年.在巴西Belem召开的全美洲灵长类会议上,一些狨猴种群的管理人员讨论了一种他们都曾观

关键词：正常体重综合征综合病症 wasting 体重减轻

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Malnutrition Prevalence in Lasa Xizang Children and Adolescents

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Biomedical and Environmental Sciences 2014年第8期27卷 614-626页

作者： YIN Xiao Jian JI Cheng Ye Key Laboratory of Adolescent Health Assessment and Exercise Intervention Ministry of Education College of Physical Education & Health East China Normal University Institute of Child and Adolescent Health Peking University Health Science Center

Objective To assess the prevalence of malnutrition among children and adolescents in Xizang （Tibet）. Methods We analyzed data from the Chinese National Survey on Students＇ Constitution and Health for the years 1995, 2000, 2005, and 2010 pertaining to Tibetan children and adolescents in Lase （Lhasa）, aged 7-18 years old. Numbers of survey subjects for these years were：2 393, 2 754, 2 397, and 2 643, respectively. Results Our results indicated that the rate of occurrence of stunting in Tibet has evidenced a gradual decline：for boys, from 26.8%in 2000 to 9.3%in 2010;and for girls, from 25.8%in 2000 to 10.8%in 2010. In general, the wasting rate for both boys and girls in Tibet has gradually decreased over time：for boys, from 17.7%in 1995 to 4.6%in 2005;and for girls from 12.5%in 1995 to 2.3%in 2005. The stunting rates of boys aged 7-13 years old and of girls aged 7-11 years old were 67.5%and 53.1%, respectively, while these rates for boys aged 14-18 years old and girls aged 12-18 years old were 32.5%and 46.9%, respectively. Conclusion Stunting and wasting rates of Tibetan children and adolescents indicate a gradual declining trend over time. The stunting rates of both boys and girls during early puberty were significantly higher than those during late puberty.

关键词： Tibetan children and adolescents Malnutrition Stunting wasting

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Co-morbidity of malnutrition with falciparum malaria parasitaemia among children under the aged 6-59 months in Somalia:a geostatistical analysis

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Infectious Diseases of Poverty 2018年第1期7卷 714-722页

作者： Damaris K.Kinyoki Grainne M.Moloney Olalekan A.Uthman Elijah O.Odundo Ngianga-Bakwin Kandala Abdisalan M.Noor Robert W.Snow James A.Berkley Spatial Health Metrics Group INFORM ProjectKenya Medical Research Institute/Wellcome Trust Research ProgrammeNairobiKenya Nutrition Section United Nations Children’s Fund(UNICEF)Kenya Country OfficeUN Complex GigiriNairobiKenya Warwick Medical School Health Sciences Research InstituteWarwick EvidenceUniversity of WarwickGibbet HillCoventry CV47ALUK Food Security and Nutrition Analysis Unit(FSNAU)-Somalia Food and Agriculture Organization of the United NationsNgecha Road CampusNairobiKenya Department of Mathematics and Information sciences Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle upon TyneUK Faculty of Health and Sport Sciences University of AgderKristiansandNorway Division of Epidemiology and Biostatistics School of Public HealthUniversity of the WitwatersrandJohannesburgSouth Africa Kenya Medical Research Institute/Wellcome Trust Research Programme Centre for Geographic Medicine Research(coast)KilifiKenya Centre for Tropical Medicine and Global Health Nuffield Department of Clinical MedicineUniversity of OxfordCCVTMOxford OX37LJUK

Background:Malnutrition and malaria are both significant causes of morbidity and mortality in African ***,the extent of their spatial comorbidity remains unexplored and an understanding of their spatial correlation structure would inform improvement of integrated *** aimed to determine the spatial correlation between both wasting and low mid upper arm circumference(MUAC)and falciparum malaria among Somalian children aged 6-59 ***:Data were from 49227 children living in 888 villages between 2007 to *** developed a Bayesian geostatistical shared component model in order to determine the common spatial distributions of wasting and falciparum malaria;and low-MUAC and falciparum malaria at 1×1 km spatial ***:The empirical correlations with malaria were 0.16 and 0.23 for wasting and low-MUAC *** spatial residual effects were statistically significant for both wasting and *** posterior spatial relative risk was highest for low-MUAC and malaria(range:0.19 to 5.40)and relatively lower between wasting and malaria(range:0.11 to 3.55).Hotspots for both wasting and low-MUAC with malaria occurred in the South Central region in ***:The findings demonstrate a relationship between nutritional status and falciparum malaria parasitaemia,and support the use of the relatively simpler MUAC measurement in *** spatial distribution and distinct hotspots present opportunities for targeted seasonal chemoprophylaxis and other forms of malaria prevention integrated within nutrition programmes.

关键词： Malnutrition wasting Low-MUAC Malaria Comorbidity Somalia

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