检索结果-南通市图书馆

Effects of Vagal and Sympathetic Nerves on transmembrane potential of Cardiac Ventricular Cells of Toad

Journal of Medical Colleges of PLA 1987年第3期 219-222页

作者： Jin Jiabu Wang Yunxiang Qin Chaoji Department of Physiology,Fourth Military Medical College,Xi’an

The effects of vagal and sympathetic nerves on the transmembranepotentials of cardiac cells of toad were observed by means of *** vagal nerve was stimulated there would be an increase in restingpotential and acceleration in repolarization of action potential(AP).However,ifatropine was used before stimulation the above-mentioned phenomena *** the sympathetic nerve was stimulated the AP amplitudeincreased,but resting potential(RP)remained the *** increase of APresulted from the increases of *** the sympathetic nerve wasstimulated although the heart rate increased and the duration of AP wasshortened,the plateau phase of AP was *** results suggest that theeffects of vagal and sympathetic nerves on the transmembrane potential of cardiacventricular cells are coordinated and the normal characteritics of transmembranepotential are maintained by both the vagal and sympathetic nerves.

关键词： vagal nerve sympathetic nerve action potential transmembrane potential microelectrode technique atropine bufo-bufo

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Analysis of Cell Circuit Model and Simulation of transmembrane potential

Analysis of Cell Circuit Model and Simulation of Transmembra...

引用

第30届中国控制与决策会议

作者： Lv Donghao Li Shuo Li Ailian Du Yongxing School of Information Engineering Inner Mongolia University of Science and Technology

A more realistic multi-channel cellular model, which is based on the classic spherical single-cell dielectric model and takes into account the influence of different parts of the cell on the transmembrane potential, is proposed. Methods for calculating transmembrane potential of cytomembrane and nuclear envelope and modeling the transfer function of each part of the cell membrane voltage are introduced. The experimental results show that different cells have different membrane voltage response to the same parameters of electrical pulse, which also explains that the stimulating effect for electrical pulses to the cell is selective. The optimal pulse parameters which are suitable for tumor treatment can be found and that could achieve a better therapeutic effect on tumor tissues and minimize the side effects on normal cells. The validity of the multi-channel cellular circuit model has been verified.

关键词： Cell Circuit Model transmembrane potential Irreversible Electroporation Simulation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effects of abnormal excitation on the dynamics of spiral waves

引用

Chinese Physics B 2016年第1期25卷 501-506页

作者：邓敏艺张学良戴静娱 College of Physical Science and Technology Guangxi Normal University

The effect of physiological and pathological abnormal excitation of a myocyte on the spiral waves is investigated based on the cellular automaton model. When the excitability of the medium is high enough, the physiological abnormal excitation causes the spiral wave to meander irregularly and slowly. When the excitability of the medium is low enough, the physiological abnormal excitation leads to a new stable spiral wave. On the other hand, the pathological abnormal excitation destroys the spiral wave and resultsin the spatiotemporal chaos, which agrees with the clinical conclusion that the early after depolarization is the pro-arrhythmic mechanism of some anti-arrhythmic drugs. The mechanisms underlying these phenomena are analyzed.

关键词： cellular automaton abnormal excitation transmembrane potential spiral wave

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ethanol induced mitochondria injury and permeability transition pore opening: Role of mitochondria in alcoholic liver disease

引用

World Journal of Gastroenterology 2007年第16期13卷 2352-2356页

作者： Ming Yan Ping Zhu Hui-Min Liu Hai-Tao Zhang Li Liu Department of Digestive Diseases Qilu Hospital Shandong University Jinan 250012 Shandong Province China Jinan Infectious Disease Hospital Jinan 250012 ShandongProvince China

AIM: To observe changes of mitochondria and investigate the effect of ethanol on mitochondrial perme- ability transition pore (PTP), mitochondrial membrane potential (MMP, ΔΨm) and intracellular calcium concentration in hepatocytes by establishing an animal model of alcoholic liver disease (ALD). METHODS: Fourty adult male Wistar rats were randomly divided into two groups, the model group (20) was administered alcohol intragastrically plus an Oliver oil diet to establish an ALD model, and the control group (20) was given an equal amount of normal saline. The ultramicrostructural changes of mitochondria were observed under electron microscopy. Mitochondria of liver was extracted, and patency of PTP, mitochondrial membrane potential (ΔΨm), mitochondrial mass and intracellular calcium concentration of isolated hepacytes were detected by flow cytometry using rhodamine123 (Rh123), Nonyl-Acridine Orange and calcium fluorescent probe Fluo-3/AM, respectively. RESULTS: Membrane and cristae were broken or disappeared in mitochondria in different shapes under electron microscopy. Some mitochondria showed U shape or megamitochondrion. In the model group, liver mitochondria PTP was broken, and mitochondria swelled, the absorbance at 450 nm, A540 decreased (0.0136 ± 0.0025 vs 0.0321 ± 0.0013, model vs control, P transmembrane potential (239.4638 ± 12.7263 vs 377.5850 ± 16.8119, P potential and injury, and elevated intracellular Ca2+ production. Ethanol-induced chondriosome injury may be an important mechanism of alcoholic diseases.

关键词： Alcoholic liver disease Chondriosome Apoptosis Ultra microstructure Membrane potentials Permeability transition pore transmembrane potential chondriosome mass Ca^2+

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

How Does the Slow Injection of a Medicine under the Influence of a Magnetic Field Affects the Spreading of Medical Substances

引用

Journal of Applied Mathematics and Physics 2021年第12期9卷 3115-3121页

作者： N. G. Gulko I. T. Selezov Department of Mathematics Ben-Gurion University of the Negev Beer-Sheva Israel Institute of Hydromechanics NAS of Ukraine Kiev Ukraine

The problem of excitation and the propagation of a nerve impulse by an axon (nerve fiber) for the case of a noninstantaneous function is studied. The application of no instantaneous step function of the Heaviside type takes into account the time of delay. This generalizes the problem of the propagation of axon excitation to the case of an input impulse function’s noninstantaneous action with some increasing excitation. An exact analytical solution to the problem is constructed based on the Laplace integral transform and Ephros theorem. The propagation of the transmembrane potential was studied, in response to the switching on and off, for impulse of a constant current pulse delivered intracellularly at different points in time. The time analysis of excitation propagation along axon at different distances from the excitation point was performed.

关键词： Noninstantaneous Excitation Heaviside Function transmembrane potential Ephros Theorem Laplace Transform

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：