检索结果-南通市图书馆

Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopathy

引用

International Journal of Ophthalmology(English edition) 2013年第4期6卷 531-536页

作者： Emrullah Beyazyildiz Ali Bülent ankaya Esra Ergan Mustafa Alparslan Anayol Yasemin zdamar Sevilay Sezer Mehmet Hakan Tirhis Pelin Yilmazbas Faruk ztürk Department of Ophthalmology Gazi Mustafa Kemal State HospitalAnkara 06900Turkey Department of Ophthalmology Ulucanlar Eye Research and Training HospitalAnkara 06900Turkey Department of Ophthalmology Van Government HospitalVanAnkara 06900Turkey Department of Biochemistry Numune Research and Training HospitalAnkara 06900Turkey

AIM:To measure changes of total oxidant status(TOS)and total antioxidant capacity(TAC) of aqueous humor(AH) in diabetic retinopathy(DR) patients,and to determine if there were any differences in TOS and TAC of AH in diabetic patients without retinopathy compared with non-diabetic patients.·METHODS:One hundred and three eyes of 103patients who were enrolled for cataract surgery were included in this *** were grouped according to presence of diabetes and stage of *** to cataract surgery,0.1mL to 0.2mL of AH was aspirated and analyzed for TAC and TOS level using a colorimetric method.·RESULTS:TOS levels were highest among proliferative diabetic retinopathy(PDR) patients and lowest in patients with only *** were statistically significant between all groups(P <0.05).Whereas result between diabetic without retinopathy patients and non-proliferative diabetic retinopathy(NPDR) patients was not statistically significant(P =0.757).TAC levels were highest in patients with only cataract and lowest among PDR patients and results were statistically significant between all groups(P <0.05).·CONCLUSION:Aqueous humor TAC levels are low in diabetic patients and reduced further in DR patients,TOS levels are increased in diabetic patients and this is exacerbated in DR patients.

关键词： aqueous humor diabetic retinopathy total antioxidant capacity total oxidant status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison of the impact of epigallocatechin gallate and ellagic acid in an experimental cataract model induced by sodium selenite

引用

International Journal of Ophthalmology(English edition) 2017年第4期10卷 499-506页

作者： Irfan Ergen Burak Turgut Nevin Ilhan Diskapi YildirimBeyazit Training and Research Hospital Eye Diseases Clinic Ankara 06330 Turkey Department of Ophthalmology Faculty of Medicine Firat University Elazig 23119 Turkey Department of Biochemistry Faculty of Medicine Firat University Elazig 23119 Turkey

AIM：To compare the potential protective effects of epigallocatechin gallate（EGCG） and ellagic acid（EA） in an experimental cataract model.●METHODS：Twenty-eight Spraque-Dawley rat pups were assigned into four *** the rats,except for those in the control group,were injected subcutaneously sodium selenite to induce experimental cataract on the postpartum ninth day,and between 10 th and 14 th *** in the sham,EGCG,and EA groups were intraperitoneally administered 50 mg/（kg·d） saline solution,50 mg/（kg·d） EGCG and 200 mg/（kg·d） EA,*** reduced glutathione（GSH） and malondialdehyde（MDA） levels,total antioxidant status（TAS） and total oxidant status（TOS） in lens supernatants were ***：The mean cataract gradings in EGCG and EA groups were found to be significantly lower than that in sham group（P〈0.001）.The mean GSH levels and TASs in EGCG and EA groups were significantly higher than that in sham group while mean MDA levels and TOSs in EGCG and EA groups were significantly lower than that in the sham group（P〈0.001）.CONCLUSION：EGCG and EA have protective effects on cataract development via the inhibition of oxidative stress.

关键词： sodium selenite experimental cataract epigallocatechin gallate ellagic acid total oxidant status totalanti-oxidant status.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of walnut(Juglans regia L.)kernel extract and juglone on dopamine levels and oxidative stress in rats

引用

Food Bioscience 2023年第1期51卷 906-913页

作者： Sener Cintesun Zeynep Ozman Abdurrahim Kocyigit Banu Mansuroglu Ismail Kocacaliskan Department of Molecular Biology and Genetics Faculty of Arts&ScienceYıldız Technical UniversityIstanbulTurkey Faculty of Medicine Department of Medical BiochemistryBezmialem Vakif UniversityIstanbulTurkey Institute of Health Sciences Department of Medical BiochemistryBezmialem Vakif UniversityIstanbulTurkey Advanced Research and Application Center of Traditional and Complementary Medicine Bezmialem Vakif UniversityIstanbulTurkey

3,4-dihydroxyphenethylamine(dopamine)is a neurotransmitter that has vital functions in the nervous *** metabolism and reactive oxygen species(ROS)production are highly related *** present study aims to evaluate the effects of walnut(Juglans regia L.)extract(WE)and 5-hydroxy-1,4 naphthoquinone(juglone)on dopamine levels and oxidative *** this purpose,WE and juglone were administered to *** and brain dopamine levels,total oxidant status(TOS),and total antioxidant status(TAS)were measured after 21 *** oxidative stress index(OSI)was ***(300 mg/kg)significantly increased brain dopamine *** and juglone reduced oxidative stress in liver and brain tissues compared to *** results revealed that WE and juglone might have a neuroprotective *** studies are needed to extensively investigate the molecular mechanism of the effects of herbal extracts and phenolic compounds on brain health.

关键词： Dopamine Walnut Juglone total antioxidant status total oxidant status Oxidative stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients

引用

Asian Pacific Journal of Tropical Biomedicine 2017年第3期7卷 249-252页

作者： Atheer Awad Mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman Department of Biotechnology Engineering College of EngineeringInternational Islamic University MalaysiaKuala Lumpur50728Malaysia Department of Technical Medical Analysis College of Health and Medical TechnologyMiddle Technical UniversityBaghdad10047Iraq Department of Chemistry College of Sciences for WomenUniversity of BaghdadBaghdad10071Iraq Department of Chemistry College of SciencesUniversity of BaghdadBaghdad10071Iraq College of Science International Islamic University MalaysiaKuantan25200Malaysia Department of Urology Hospital Tengku Ampuan AfzanKuantan25200Malaysia Department of Pathology Hospital Tengku Ampuan AfzanKuantan25200Malaysia

Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2(NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis ***: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ***: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly ***: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis.

关键词： Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 total oxidant status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

oxidant/antioxidant balance in the aqueous humor of patients with glaucoma

引用

International Journal of Ophthalmology(English edition) 2016年第2期9卷 249-252页

作者： Esra Ergan Faruk Ozturk Emrullah Beyazyildiz Ufuk Elgin Emine Sen Ali Bulent Cankaya Tugrul Celik Department of Ophthalmology Amasya UniversitySabuncuoglu Serefeddin Research and Training Hospital Department of Ophthalmology Hacettepe University Department of Ophthalmology Samsun Research and Training Hospital Department of Opthalmology Ulucanlar Eye Research Hospital Department of Biochemistry Turgut Ozal University

AIM： To evaluate total antioxidant status （TAS）, total oxidant status （TOS）, and the oxidative stress index （OSI） of the aqueous humor （AH） in patients with glaucoma. METHODS： The prospective study was composed of a study group （n-31） and a control group （n=31）. Fifteen patients in the study group were diagnosed with primary open angle glaucoma （POAG）, and 16 patients were diagnosed with pseudoexfoliation glaucoma （PEG）. The control group was composed of non-glaucomatous patients with cataracts. AH samples were collected and analyzed for TAS, TOS, and OSI levels. RESULTS： Mean AH TAS level was significantly higher in patients with glaucoma than that in the control group （P〈0.01）. Mean TOS and OSI levels tended to increase in patients with glaucoma. No significant differences in TAS, TOS, or OSI levels were observed between patients with POAG and PEG. CONCLUSION： High levels of TAS were observed in patients with glaucoma, which was likely a response to the increased oxidative stress observed in these patients.

关键词： oxidative stress primary open angleglaucoma pseudoexfoliation glaucoma total antioxidantstatus total oxidant status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insulin resistance in H pylori infection and its association with oxidative stress

引用

World Journal of Gastroenterology 2006年第42期12卷 6865-6868页

作者： Mehmet Aslan Mehmet Horoz Yasar Nazligul Cengiz Bolukbas F Fusun Bolukbas Sahbettin Selek Hakim Celik Ozcan Erel Department of Internal Medicine Faculty of Medicine Harran University Sanliurfa Turkey Department of Gastroenterology Faculty of Medicine Harran University Sanliurfa Turkey Department of Clinical Biochemistry Faculty of Medicine Harran University Sanliurfa Turkey

AIM: To determine the insulin resistance (IR) and oxidative status in H pylori infection and to find out if there is any relationship between these parameters and insulin resistance. METHODS: Fifty-five H pylori positive and 48 H pylori negative patients were enrolled. The homeostasis model assessment (HOMA) was used to assess insulin resistance. Serum total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined in all subjects. RESULTS: The total antioxidant capacity was significantly lower in H pylori positive group than in H pylori negative group (1.36 ± 0.33 and 1.70 ± 0.50, respectively; P total oxidant status and oxidative stress index were significantly higher in H pylori positive group than in H pylori negative group (6.79 ± 3.40 and 5.08 ± 0.95, and 5.42 ± 3.40 and 3.10 ± 0.92, respectively; P total antioxidant capacity (r = -0.251, P total oxidant status (r = 0.365, P oxidant vitamins to H pylori eradication therapy on insulin resistance during H pylori infection.

关键词： Hpylori Insulin resistance total antioxidant capacity total oxidant status Oxidative stress index

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Therapeutic Uses of Lycium barbarum Polysaccharides on Idiopathic Thrombocytopenic Purpura Mice via Inhibition of Oxidative Stress

引用

Journal of Biosciences and Medicines 2016年第8期4卷 17-23页

作者： Chengqiang Jin Haixin Dong Jianwei Zhou Shuhua Lu Xiaxia Yang Zhenwen Qian Yanxia Jia Analytical Section of Attached Hospital of Jining Medical College Jining China Radiology Department of Jining No. 1 People’s Hospital Jining China

The aim of the present study was to investigate the effect of Lycium barbarum polysaccharides (LBP) on the treatment of ITP mice and to explore its mechanism. Forty idiopathic thrombocytopenic purpura (ITP) mice were divided randomly into a model control group and LBP groups I, II, III and IV. ITP mice in LBP groups I, II, III, and IV were administered LBP at four different doses (50, 100, 200 and 400 mg·kg-1·d-1, respectively) for 7 days by gavage. Blood samples were collected from the tail veins of the mice after treatment. Platelet counts were determined, and the total antioxidant status (TAS), total oxidant status (TOS) were measured with ELISA kits. The platelet count was (30.28 ± 13.42) × 109/L in the model control group, and the number of platelets in all LBP groups was higher than that in the model control group. The platelet count increased, and it reached (67.09 ± 10.81) × 109/L in LBP group I;the platelet counts in the other three groups increased significantly compared to LBP group I, and they did not differ significantly. TAS concentrations in the LBP groups were significantly increased compared to the model control group, whereas TOS concentrations were significantly decreased. Taken together, these results indicate that LBP is effective at increasing the number of platelet (PLT), and LBP may treat ITP mice via suppressing oxidative stress.

关键词： Lycium barbarum Polysaccharides Idiopathic Thrombocytopenic Purpura total Antioxidant status total oxidant status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：