检索结果-南通市图书馆

Practical choice for robust and efficient differentiation of human pluripotent stem cells

World Journal of Stem Cells 2020年第8期12卷 752-760页

作者： Mei Fang Li-Ping Liu Hang Zhou Yu-Mei Li Yun-Wen Zheng Institute of Regenerative Medicine Affiliated Hospital of Jiangsu UniversityJiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina School of Biotechnology and Heath Sciences Wuyi UniversityJiangmen 529020Guangdong ProvinceChina Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery University of Tsukuba Faculty of MedicineTsukubaIbaraki 305-8575Japan City University School of Medicine YokohamaKanagawa 234-0006Japan Division of Regenerative Medicine Center for Stem Cell Biology and Regenerative MedicineThe Institute of Medical Sciencethe University of TokyoTokyo 108-8639Japan

Human pluripotent stem cells(hPSCs)have the distinct advantage of being able to differentiate into cells of all three germ *** cells or tissues derived from hPSCs have many uses such as drug screening,disease modeling,and transplantation *** are currently a wide variety of differentiation methods ***,most of the existing differentiation methods are unreliable,with uneven differentiation efficiency and poor *** the same time,it is difficult to choose the optimal method when faced with so many differentiation schemes,and it is time-consuming and costly to explore a new differentiation ***,it is critical to design a robust and efficient method of *** this review article,we summarize a comprehensive approach in which hPSCs are differentiated into target cells or organoids including brain,liver,blood,melanocytes,and mesenchymal *** was accomplished by employing an embryoid body-based three-dimensional(3D)suspension culture system with multiple cells *** method has high stable differentiation efficiency compared to the conventional 2D culture and can meet the requirements of clinical ***,ex vivo co-culture models might be able to constitute organoids that are highly similar or mimic human organs for potential organ transplantation in the future.

关键词： Human pluripotent stem cells three dimensional Embryoid body Differentiation Efficient three germ layers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：