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Double-authentication-preventing signatures revisited:new definition and construction from chameleon hash

Frontiers of Information Technology & Electronic Engineering 2019年第2期20卷 176-186页

作者： Fei LI Wei GAO Gui-lin WANG Ke-fei CHEN Chun-ming TANG School of Mathematics and Statistics Ludong University Key Laboratory of Information Security Guangzhou University China-USA Computer Science Research Center Nanjing University of Information Science and Technology Shield Lab Singapore Research Center of Huawei Department of Mathematics Hangzhou Normal University

Double-authentication-preventing signature(DAPS) is a novel signature notion proposed at ESORICS2014. The double-authentication-preventing property means that any pair of signatures on two different messages with the same subject will result in an immediate collapse of the signature system. A few potential applications of DAPS have been discussed by its inventors, such as providing a kind of self-enforcement to discourage certificate authority(CA) from misbehaving in public key infrastructure and offering CA some cryptographic arguments to resist legal coercion. In this study, we focus on some fundamental issues on DAPS. We propose a new definition,which is slightly weakened but still reasonable and strong enough to capture the DAPS concept. We develop the new notion of invertible chameleon hash functions with key exposure. Then we propose a generic DAPS scheme, which is provably secure if the underlying invertible chameleon hash function with key exposure is secure. We instantiate this general construction to obtain the DAPS schemes respectively based on the well-known assumptions of integer factorization, Rivest-Shamir-Adleman(RSA), and computational Diffie-Hellman(CDH). They are more efficient than previous DAPS schemes. Furthermore, unlike previous constructions, the trusted setup condition is not needed by our DAPS schemes based on RSA and CDH.

关键词： Double-authentication-preventing signatures Chameleon hash function Digital signature Provable security Authority trust level

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Spectroscopic signatures of edge states in hexagonal boron nitride

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Nano Research 2019年第7期12卷 1663-1667页

作者： Chuang Gao Lei Tao Yu-Yang Zhang Shixuan Du Sokrates T. Pantelides Juan Carlos Idrobo Wu Zhou Hong-Jun Gao School of Physical Sciences and CAS Key Laboratory of Vacuum Physics University of Chinese Academy of SciencesBeijing 100049China Institute of Physics Chinese Academy of SciencesBeijing 100190China Department of Physics and Astronomy and Department of Electrical Engineering and Computer Science Vanderbilt UniversityNashvilleTN 37235USA CAS Centre for Excellence in Topological Quantum Computation University of Chinese Academy of SciencesBeijing 100049China Center for Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTN 37831USA

We use Z-contrast imaging and atomically resolved electron energy-loss spectroscopy on an aberration-corrected scanning transmission electron microscope to investigate the local electronic states of boron atoms at different edge structures in monolayer and bilayer h-BN.We find that edges with bonding unsaturated sp2 boron atoms have a unique spectroscopic signature with a prominent pre-peak at - 190.2 eV in the B K-edge fine structure.First-principles calculations reveal that the observed pre-peak arises from excitations to the in-plane lowest-energy empty sp2 boron dangling bonds at the B-terminated edge.This spectroscopic signature can serve as a fingerprint to explore new edge structures in h-BN.

关键词： h-BN edge structure spectroscopic signatures electron energy-loss near edge structure

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Transcriptomic signatures decode Th17 cell pathogenicity

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Cellular & Molecular Immunology 2016年第5期13卷 557-559页

作者： PA Reyfman ET Bartom BD Singer Northwestern University Feinberg School of Medicine Department of Medicine Division of Pulmonary and Critical Care Medicine Chicago IL 60611 USA Northwestern University Feinberg School of Medicine Department of Biochemistry and Molecular Genetics Chicago IL 60611 USA

Systems immunology is a growing field that attempts to integrate high-throughput experiments with sophisticated computational analysis and modeling approaches. In the field of systems immunology, single-cell transcrip- tomic profiling （RNA-seq） is an experimental technique that has proven effective for delineating molecular heterogeneity within immune cell subtypes.

关键词： Transcriptomic signatures decode

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Genome-wide detection of selective signatures in a Jinhua pig population

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Journal of Integrative Agriculture 2020年第5期19卷 1314-1322页

作者： XU Zhong SUN Hao ZHANG Zhe Zhao Qing-bo Babatunde Shittu Olasege Li Qiu-meng Yue Yang Ma Pei-pei Zhang Xiang-zhe Wang Qi-shan Pan Yu-chun Department of Animal Science School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240P.R.China Shanghai Key Laboratory of Veterinary Bio-technology Shanghai 200240P.R.China

The aim of this study was to detect evidence for signatures of recent selection in the Jinhua pig genome.These results can be useful to better understand the regions under selection in Jinhua pigs and might shed some lights on groups of genes that control production traits.In the present study,we performed extended haplotype homozygosity(EHH)tests to identify significant core regions in 202 Jinhua pigs.A total of 26161 core regions spanning 636.42 Mb were identified,which occupied approximately 28%of the genome across all autosomes,and 1158 significant(P<0.01)core haplotypes were selected.Genes in these regions were related to several economically important traits,including meat quality,reproduction,immune responses and exterior traits.A panel of genes including ssc-mir-365-2,KDM8,RABEP2,GSG1L,RHEB,RPH3AL and a signal pathway of PI3K-Akt were detected with the most extreme P-values.The findings in our study could draw a comparatively genome-wide map of selection signature in the pig genome,and also help to detect functional candidate genes under positive selection for further genetic and breeding research in Jinhua and other pigs.

关键词： pig genome selection signatures extended haplotype homozygosity(EHH) candidate genes

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Mapping Supergene/Hypogene Alteration signatures with Landsat ETM+ Data: Paishanlou Gold Mine, Liaoning Province, China

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Journal of China University of Geosciences 2005年第1期16卷 38-44页

作者： Malogo J M Kongola School of Resources and Civil Engineering Northeastern University Shenyang 110004 China

Noise removal routines (destriping) were performed on Landsat ETM+ data as adjustments for atmospheric and distortion factors, prior to further image enhancement and interpretation. The image enhancement techniques were contrast stretching, density slicing, spatial filtering, Fourier analysis, brightness inversion, band combinations, and band ratioing. It has been revealed that, owing to the presence of gossans at Paishanlou, the mixture of iron oxide and clay minerals affects the spectral reflectance in satellite data. The mineral and hydrothermal composite images with band ratios 5/7+5/4+3/1 RGB and 5/7+3/1+4/3 RGB, respectively, yielded the best results for their sensitivity to lithologic variables, and lack of statistical redundancy. Ratio 3/1 clearly highlighted ferric (Fe 3+ ) iron; 5/4 depicted ferrous (Fe 2+ ) iron, and 5/7 depicted clays, carbonates, and hydroxyl bearing minerals. Vegetation was also successfully discriminated by ratio 5/7. Finally, coupled with field surveys, petrographical and geochemical data, the observed anomalies led to the discovery of three new sites, which are gold mineralized. The prime objective of this study was to map supergene and/or hypogene signatures in the gold mineralized areas using Landsat ETM+ data at Paishanlou.

关键词： gold signatures hypogene/supergene alteration Landsat ETM+.

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Static Digits Recognition Using Rotational signatures and Hu Moments with a Multilayer Perceptron

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Engineering（科研） 2014年第11期6卷 692-698页

作者： Francisco Solís Margarita Hernández Amelia Pérez Carina Toxqui Autonomous University of Mexico State Toluca Mexico Polytechnic University of Tulancingo Tulancingo Mexico

This paper presents two systems for recognizing static signs (digits) from American Sign Language (ASL). These systems avoid the use color marks, or gloves, using instead, low-pass and high-pass filters in space and frequency domains, and color space transformations. First system used rotational signatures based on a correlation operator;minimum distance was used for the classification task. Second system computed the seven Hu invariants from binary images;these descriptors fed to a Multi-Layer Perceptron (MLP) in order to recognize the 9 different classes. First system achieves 100% of recognition rate with leaving-one-out validation and second experiment performs 96.7% of recognition rate with Hu moments and 100% using 36 normalized moments and k-fold cross validation.

关键词： Sign Language Recognition Rotational signatures Hu Moments Multi-Layer Perceptron

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Metabiotics: The Functional Metabolic signatures of Probiotics: Current State-of-Art and Future Research Priorities—Metabiotics: Probiotics Effector Molecules

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Advances in Bioscience and Biotechnology 2018年第4期9卷 147-189页

作者： Aarti Singh Vishakha Vishwakarma Barkha Singhal School of Biotechnology Near Kasna Road Gautam Buddha University Greater Noida (U.P.) India

The intricate “orchestered molecular conversation” between the host and gut microbiome is one of the most dynamic research areas in recent years. The rhythmic chemical cross talk in the form of bioactive metabolites and signalling molecules synthesized by gut microbiome plays a significant role for the modulation of human health in diversified ways. They are recognized as low molecular weight (LMW) molecules having versatile chemical attributes. They possess magnificent capability of interacting with surrounding environment and controlling the genes for various genetic, biochemical and physiological functions for maintaining the homeostasis that is now-a-days termed as “small molecules microbes originated (SMOM) homeostasis” in the host. These metabolic signatures have close structural and functional resemblance with small molecules synthesized by host eukaryotic cells and dietary components. Therefore, they may be considered as universalized metabolites contributing to the remarkable phenomenon of epigenetic regulation, cell to cell communication and stability of genome manifesting the overall growth and development of the host and known as “metabiotics”. The wide panorama of utilization of probiotics is continuously expanding and conferring the major health benefits through metabiotic components are gaining tremendous momentum therefore recognized as “hidden soldiers” of the body. Therefore firstly, we outline the need and types of metabiotic molecules and depicting their role in human health. Then, we summarize their preventive and therapeutic avenues in various diseases and finally, we propose the current technological interventions, bottlenecks and future perspectives in this field that are implied for accelerating their comprehensive understanding and utilization at industrial scale.

关键词： Metabiotics Probiotics Metabolic signatures Gut Microbiome Homeostasis

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An Algorithm for Generation of Attack signatures Based on Sequences Alignment

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Journal of Software Engineering and Applications 2008年第1期1卷 76-82页

作者： Nan Li Chunhe Xia Yi Yang HaiQuan Wang Beihang University

This paper presents a new algorithm for generation of attack signatures based on sequence alignment. The algorithm is composed of two parts: a local alignment algorithm-GASBSLA (Generation of Attack signatures Based on Sequence Local Alignment) and a multi-sequence alignment algorithm-TGMSA (Tri-stage Gradual Multi-Sequence Alignment). With the inspiration of sequence alignment used in Bioinformatics, GASBSLA replaces global alignment and constant weight penalty model by local alignment and affine penalty model to improve the generality of attack signatures. TGMSA presents a new pruning policy to make the algorithm more insensitive to noises in the generation of attack signatures. In this paper, GASBSLA and TGMSA are described in detail and validated by experiments.

关键词： Attack signatures Generation Sequence Local Alignment Affine Penalty Intrusion Detection Pruning Policy

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Identification of regulatory sequence signatures in microRNA precursors implicated in neurological disorders

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Advances in Bioscience and Biotechnology 2013年第5期4卷 26-33页

作者： Sayak Ganguli Sasti Gopal Das Hirak Jyoti Chakraborty Sohini Gupta Abhijit Datta DBT Centre for Bioinformatics Presidency University Kolkata India

MicroRNAs have emerged as one of the major classes of non-coding RNAs. Recent reports have placed them in high abundance in the nervous system, having key roles in development. Neurological disorders such as Parkinson’s disease, Alzheimer’s disease as well as Huntington disease have also been studied and several microRNAs associated with diseases pathogenesis have been identified. Various such findings indicate differential expression levels of many of these microRNAs. Such changes in the expression levels not only indicate towards a control of the biogenesis of these microRNAs but also indicate towards critical yet unelucidated roles of regulatory proteins, which probably act in concert to control the production or maturation of these molecules. In this work, a collection of overrepresented regulatory motif signatures were identified in the DNA and RNA sequences of the precursor microRNAs. The identification of such regulatory sequence signatures promises to provide new insights into many facets of microRNA regulation and neurological disorders.

关键词： Neurological Diseases Regulatory Motif signatures Parkinson’s Disease Alzheimer’s Disease Huntington Disease

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Molecular Footprint of Kenya’s Gene Bank Repositories Based on the <i>cp</i>-Genome signatures

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American Journal of Molecular Biology 2018年第4期8卷 215-244页

作者： Okoth Patrick Muoma John Omayio Dennis Barasa Mustafa Angienda Paul Department of Biological Sciences Masinde Muliro University of Science and Technology Kakamega Kenya Department of Zoology School of Physical and Biological Sciences Maseno University Private Bag Maseno Kenya Department of Medical Laboratory Sciences (MLS) Masinde Muliro University of Science and Technology Kakamega Kenya

While the mutational processes that subsume biological diversity can be revealed in great detail through phylogenetic inferencing using plastid markers, few studies document their use. Accurate phylogenic inference can provide a framework for addressing a host of important evolutionary questions including a context to reconstruct molecular evolution of an organism. Despite the obvious utility of plastid markers in illuminating biological enquiry, many important questions still abound. The use of cp-DNA gene sequence data for phylogenetic inference can have an enormous impact on plant phylogenetics and systematics. The repertoire of genetic diversity of Kenya’s Gene Bank repositories can be explored based on cp-genome signatures. This is because cp-DNA-based mutational changes are an important additional tool to the previous evidence available on plant evolution yet to be explored in biodiversity studies in Kenya. Taken together, these evolutionary changes can inspire development of realistic algorithms for phylogenetic inferencing based on molecular data. Phylogenetic reconstructions are at the very core of molecular evolution. Comparative sequence analyses of plastid markers can have utility beyond the study of phylogeny. The pattern of nucleotide substitution observed over evolutionary time can reflect functional constraints imposed due to natural selection. In line with this, it is possible to detect subtle anatomical variations associated with small fitness effects that can account for genetic diversity at varietal level. The lack of sequence information in Kenyan cowpea has limited the robust advancement of molecular markers use in dissecting diversity based on the putative plastid markers?[1]. The present study sought to generate and upscale novel technologies such as genomics, DNA barcoding and bio-informatics in understanding molecular diversity of cowpea accessions from the Gene Bank of Kenya and ecotypes. A total of 298 sequences of cowpea germplasm conserved as in situ and ex situ in Kenya but sourced

关键词： DNA Barcoding Molecular Phylogeny Molecular Diversity Plastid Markers Genome signatures Genotyping NCBI

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