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Successful management of a mixed epithelial and stromal renal tumor masquerading as lower pole renal cyst:A laparoscopic deroofing approach

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UroPrecision 2024年第1期2卷 36-39页

作者： Alain M.Mukendi Emelia K.C.de Heer-Menlah Phaladi Charles E.Mathye Department of Surgery Division of UrologyHelen Joseph HospitalUniversity of the WitwatersrandJohannesburgSouth Africa

Background:renal cysts are common in clinical practice,but some may harbor rare pathological entities such as mixed epithelial and stromal tumors(MEST).Imaging studies are crucial for accurate *** laparoscopic deroofing is an established approach for symptomatic renal cysts,encountering MEST within a cyst is *** Presentation:We present the case of a 37-year-old female who presented with persistent left flank *** revealed a large renal cyst in the lower pole of the left kidney,classified as Bosniak *** analgesia,the patient's symptoms persisted,leading to a laparoscopic deroofing *** examination postprocedure revealed a *** patient reported complete resolution of symptoms at the 3-month ***:This unique case presents the successful identification and surgical management of a MEST masquerading as a lower pole renal cyst through laparoscopic *** also contributes to the existing literature by highlighting the importance of considering rare pathological entities in the evaluation of renal cysts and the value of laparoscopic techniques in their management.

关键词： laparoscopic deroofing mixed epithelial and stromal tumor renal cyst renal tumor

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu Ke Wang Jia-Zhu Wen Li-Kang Luo Jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： renal tumor renal parenchyma Squamous cell carcinoma renal calculi Computed tomography Case report

“Zero ischemia”laparoscopic partial nephrectomy by high-power GreenLight laser enucleation for renal carcinoma:A single-center experience

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World Journal of Clinical Cases 2022年第17期10卷 5646-5654页

作者： Xiang-Min Zhang Ji-Dong Xu Jian-Min Lv Xiu-Wu Pan Jian-Wei Cao Jian Chu Xin-Gang Cui Department of Urology Xinhua HospitalShanghai Jiaotong UniversitySchool of MedicineShanghai 200092China Department of Urology Shanghai Baoshan Luodian HospitalShanghai 201908China Department of Urology Gongli Hospital of The Second Military Medical UniversityShanghai 200135China Department of Urology Shanghai The Seventh People's HospitalShanghai 200137China

BACKGROUND Laparoscopic partial nephrectomy has been widely used in renal cell carcinoma *** efficacy of GreenLight laser on Laparoscopic partial nephrectomy is still *** To present the first series of laparoscopic partial nephrectomy(LPN)by GreenLight laser enucleation without renal artery *** to the excellent coagulation and hemostatic properties of the laser,laser-assisted LPN(LLPN)makes it possible to perform a“zero ischemia”*** Fifteen patients with T1a exogenous renal tumors who received high-power GreenLight laser non-ischemic LPN in our hospital were retrospectively *** clinical information,surgical and post-operative data,complications,pathological and functional outcomes were *** Surgery was successfully completed in all patients,and no open or radical nephrectomy was *** renal artery was not clamped,leading to no ischemic *** blood transfusions were required,the average hemoglobin level ranged from 96.0 to 132.0 g/L and no postoperative complications *** mean operation time was 104.3±8.2 *** postoperative removal of negative pressure drainage time ranged from 5.0 to 7.0 d,and the mean postoperative hospital stay was 6.5±0.7 *** serious complications *** pathological results showed clear cell carcinoma in 12 patients,papillary renal cell carcinoma in 2 patients,and hamartoma in 1 *** mean creatinine level was 75.0±0.8μmol/L(range 61.0-90.4μmol/L)at 1 mo after surgery,and there were no statistically significant differences compared with pre-operation(P>0.05).The glomerular filtration rate ranged from 45.1 to 60.8 mL/min,with an average of 54.0±5.0 mL/min,and these levels were not significantly different from those before surgery(P>0.05).CONCLUSION GreenLight laser has extraordinary cutting and sealing advantages when used for small renal tumors(exogenous tumors of stage T1a)during ***,use of this technique can lead to the generation

关键词： GreenLight laser Zero ischemia Partial nephrectomy Laparoscopy renal tumor

Expanding the horizons of endoscopic ultrasound:diagnosis of non-digestive pathologies

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Gastroenterology Report 2014年第1期2卷 63-69页

作者： Georgios Mavrogenis Hocine Hassaini Alain Sibille Sofia Feloni Pierre H.Deprez Cedric Gillain Philippe Warzee Department of Gastroenterology Grand Hopital de CharleroiCharleroiBelgium Department of Hepato-Gastroenterology Cliniques universitaires Saint-LucUniversite Catholique de LouvainBrusselsBelgium

Endoscopic ultrasound(EUS)is mainly used for the evaluation and sampling of mediastinal and abdominal lymph nodes,luminal and submucosal lesions of the upper and lower gastrointestinal tract,as well as in the diagnostic approach for pancreatic,biliary and liver ***,several non-digestive pathologies may be encountered as well,expanding the diagnostic potential of *** this article,we present nine examples of extra-digestive abnormalities detected by means of EUS,including pathologies of the thyroid gland,mediastinal and abdominal vessels,lungs,kidney and the urinary *** purpose of this article is to review the capabilities of EUS beyond routine evaluation of gastrointestinal organs.

关键词： Endoscopic ultrasound thyroid cyst renal tumor pulmonary embolism aortic aneurysm pneumonia cardiac failure

Molecular genetics and immunohistochemistry characterization of uncommon and recently described renal cell carcinomas

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Chinese Journal of Cancer Research 2016年第1期28卷 29-49页

作者： Qiu Rao Qiu-Yuan Xia Liang Cheng Xiao-Jun Zhou Department of Pathology Jinling Hospital Nanjing University School of Medicine Nanjing China Department of Pathology and Laboratory Indiana University School of Medicine Indianapolis IN USA

renal cell carcinoma （RCC） compromises multiple types and has been emerging dramatically over the recent several decades. Advances and consensus have been achieved targeting common RCCs, such as clear cell carcinoma, papillary RCC and chromophobe RCC. Nevertheless, little is known on the characteristics of several newly-identified RCCs, including clear cell （tubulo） papillary RCC, Xpl 1 translocation RCC, t（6;11） RCC, succinate dehydrogenase （SDH）-deficient RCC, acquired cystic disease- associated RCC, hereditary leiomyomatosis RCC syndrome-associated RCC, ALK translocation RCC, thyroid-like follicular RCC, tubulocystic RCC and hybrid oncocytic/chromophobe tumors （HOCT）. In current review, we will collect available literature of these newly-described RCCs, analyze their clinical pathologic characteristics, discuss their morphologic and immunohistologic features, and finally summarize their molecular and genetic evidences. We expect this review would be beneficial for the understanding of RCCs, and eventually promote clinical management strategies.

关键词： renal cell carcinoma (RCC) renal tumor immunohistochemistry molecular genetics

Long-term oncologic outcomes of laparoscopic versus open partial nephrectomy

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Chinese Medical Journal 2013年第15期126卷 2938-2942页

作者： ZHENG Jun-hua ZHANG Xiao-long GENG Jiang GUO Chang-cheng ZHANG Xiao-peng CHE Jian-ping YAN Yang PENG Bo WANG Guang-chun XIA sheng-qiang WU Yan Tongji Univ Dept Urol Shanghai Peoples Hosp 10 Shanghai 200072 Peoples R China Nanjing Med Univ Dept Urol Clin Med Coll 1 Nanjing 210002 Jiangsu Peoples R China

Background Most of the literatures on laparoscopic partial nephrectomy （LPN） versus open partial nephrectomy （OPN） focus on technical details and early or mid-term oncologic outcomes, reflecting that the approach is safe and provides mid- term benefits compared with traditional open surgery. However, the difference of long-term oncologic outcome between LPN and OPN remains unclear. The aim of this meta-analysis was to evaluate the long-term oncologic outcome of LPN in the treatment of localized renal tumors compared with that of OPN. Methods A systematic search of electronic databases including Medline, Embase, and Cochrane library was conducted. Comparative studies reporting on long-term oncologic outcome of LPN versus OPN were regarded eligible. The odds ratio （OR） and its corresponding 95% confidence intervals （CO were calculated for the oncologic outcomes. The methodologic quality of the included studies was evaluated using the strict criteria of the Newcastle-Ottawa scale. Results Six comparative studies （1495 participants including 555 LPN and 940 OPN） were included in the present study. There was no significant difference between LPN and OPN in 5-year overall survival （OS） rates （OR=1.83, 95% Cl （0.80, 4.19））, 5-year cancer specific survival （CSS） rates （OR=1.09, 95% CI （0.62, 1.92））, and 5-year recurrence free survival （RFS） rates （OR=0.68, 95% CI （0.37, 1.26））. Conclusion The results of this meta-analysis revealed that there was no significant difference in long-term oncologic outcome between LPN and OPN for treatment of localized renal tumors.

关键词： laparoscopic partial nephrectomy meta-analysis outcome open partial nephrectomy renal tumor

renal granuloma misdiagnosed as renal papillary carcinoma: a case report

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Cancer Advances 2023年第11期6卷 1-3页

作者： Zeng-Gang Hu Nian-Yu Xue Sheng-Min Zhang Department of Ultrasonography Ninghai First HospitalNingbo 315600China Department of Ultrasonography The First Affiliated Hospital of Ningbo University(Ningbo First Hospital)Ningbo 315010China

The imaging appearance of renal granuloma is very similar to that of a renal *** lesions usually do not require surgical treatment,while kidney tumors typically necessitate surgical *** diagnosis of renal granuloma typically relies on the history of bacillus Calmette-Guérin perfusion and the position of the renal pelvis in the image(malignant tumors usually destroy or compress the surrounding renal pelvis).However,in this case,the patient has no history of bacillus Calmette-Guérin perfusion,making the diagnosis more *** ultrasound and enhanced CT findings were consistent with renal papillary *** partial nephrectomy was performed,revealing degeneration and necrosis of the renal cortex and formation of *** imaging diagnosis of renal granuloma is ***-guided biopsy may be a preferable method to avoid unnecessary surgery.

关键词： ultrasonography computed tomography renal granuloma renal tumor