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检索条件"主题词=Recombinant adenovirus"
17 条 记 录,以下是1-10 订阅
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recombinant adenovirus-mediated overexpression of 3β-hydroxysteroid-Δ24 reductase
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Neural Regeneration Research 2014年 第5期9卷 504-512页
作者: Xiuli Lu Dan Jia Chenguang Zhao Weiqi Wang Ting Liu Shuchao Chen Xiaoping Quan Deliang Sun Bing Gao Department of Biochemistry and Cell Biology School of Life ScienceLiaoning University Department of Cell Biology and Genetics School of Basic Medical Sciences Shenyang Medical College
3β-Hydroxysteroid-△24 reductase (DHCR24) is a multifunctional enzyme that localizes to the endoplasmic reticulum and has neuroprotective and cholesterol-synthesizing activities. DHCR24 overexpression confers neuro... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Optical control after transfection of channelrhodopsin-2 recombinant adenovirus in visual cortical cells
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Neural Regeneration Research 2012年 第16期7卷 1228-1233页
作者: Junping Yao Wensheng Hou Hao Wang Hui Liu Chuanhuang Weng Zhengqin Yin College of Bioengineering Chongqing UniversityChongqing 400044China Chongqing Key Lab of Visual Damage and Regeneration&Restoration Chongqing 400038China Department of Ophthalmology Southwest HospitalThird Military Medical University of Chinese PLAChongqing 400038China
Channelrhodopsin-2 ectopically expressed in the retina can recover the response to blue light in genetically blind mice and rats, but is unable to restore visual function due to optic nerve or optic tract lesions. Lon... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Co-application of ricin A chain and a recombinant adenovirus express-ing ricin B chain as a novel approach for cancer therapy
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Acta Pharmacologica Sinica 2007年 第5期28卷 657-662页
作者: Hong-bin WANG~(1,3),Fei XIA~(1,3),Jing GE~1,Juan YIN~1,Li-song TAN~4,Pei-de ZHANG~2,Jiang ZHONG~(1,5)Departments of ~1Mierobiology and Microbial Engineering and ~2Biochemistry and Molecular Biology,School of Life Sciences,FudanUniversity,Shanghai 200433,China ~3Marine College,Huaihai Institute of Technology,Lianyungang 222005,China ~4Shanghai PulmonaryHospital,Shanghai 200433,China Department of Microbiology and Microbial Engineering School of Life Sciences Fudan University Shanghai China Department of Marine College Huaihai Institute of Technology Lianyungang China Department of Shanghai Pulmonary Hospital Shanghai China Department of Biochemistry and Molecular Biology School of Life Sciences Fudan University Shanghai China
Aim:To develop a novel ricin-based approach for the safe and effective therapyof cancer.Methods:The ricin A chain (RTA) was expressed in Escherichia coli inthe form of a 6×His-tagged fusion protein and purified wit... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Construction of recombinant adenovirus Carrying GRIM19 and Its Effect on SW480 Cells
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Journal of Huazhong University of Science and Technology(Medical Sciences) 2008年 第1期28卷 14-16页
作者: 王珅 王桂华 邓豫 罗学来 李小兰 陶德定 龚建平 胡俊波 Cancer Research Institute/Department of General Surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
In order to examine the effect of GRIM19 on colon cancer cell SW480, the recombinant adenovirus carrying GRIM19 gene was constructed and transfected into SW480 cells. GRIM19 cDNA was amplified by PCR with the template... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Construction of the recombinant adenovirus vector carrying antisense multidrug resistance gene
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Hepatobiliary & Pancreatic Diseases International 2006年 第1期5卷 80-84页
作者: Bo Li, Xing-Hua Gou, Lin Chen, De-Hua Li, Yong-Heng Zhao, Lei Han, Lan-Ying Zhao and Jian-ping Gong Department of Hepatobiliary Surgery, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China Genetic Engineering Laboratory, Chengdu Diao Group Co. Ltd., Chengdu 610041, China and Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China Department of Hepatobiliary Surgery Second Affiliated Hospital Chongqing University of Medical Sciences Chongqing 400010 China.
BACKGROUND: Multidrug resistance proteins serve as transporters for chemical drugs in human malignancies. The objective of this study was to construct a homologous recombinant adenovirus carrying a reversal fragment o... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Rapid construction of phosphatase and tensin homolog-deleted on chromosome ten gene recombinant adenovirus using the AdEasy system
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Neural Regeneration Research 2010年 第15期5卷 1166-1170页
作者: Yongqiong Wei Lixue Chen Zhaofang Zeng Chongbiao Shen Key Laboratory of Laboratory Medical Diagnostics Ministry of Education Chongqing Medical University Chongqing 400016 China Chongqing Key Laboratory of Neurology First Affiliated Hospital Chongqing Medical University Chongqing 400016 China
Recent studies have shown that phosphatase and tensin homolog-deleted on chromosome ten (PTEN) gene plays an important role in ischemic brain damage and synaptic plasticity. The AdEasy system, which has been widely ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Construction of Rat Calcineurin A α cDNA recombinant adenovirus Vector and Its Identification
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Journal of Huazhong University of Science and Technology(Medical Sciences) 2006年 第1期26卷 9-12页
作者: 沈小梅 张巨艳 成蓓 Department of Cardiology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China Department of Gerontics First Affiliated Hospital Shanxi Medical University Taiyuan 030001 China
Rat calcineurin (CAN) A a isoform (Ppp3ca) cDNA recombinant adenovirus vector was constructed in order to explore the effect of CaN on the myocardium apoptosis induced by ischemia-reperfusion injury. Total RNA was... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Expression and function of DMT1 without IRE in C6 cells mediated by recombinant adenovirus
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Frontiers of Medicine 2009年 第1期3卷 67-71页
作者: Xixun DU Huamin XU Hong JIANG Jun WANG Lei WANG Junxia XIE State Key Disciplines:Physiology(in incubation) Department of PhysiologyMedical College of Qingdao UniversityQingdao 266071China
Divalent metal transporter 1(DMT1)is a ferrous iron import protein.The improper expression of DMT1 is involved in neurodegenerative diseases.In the present study,we constructed a recombinant adenovirus containing the ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Construction and Immunogenicity of a recombinant adenovirus Expressing the HA Gene of H5N1 Subtype Swine Influenza Virus
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畜牧兽医学报 2010年 第S1期41卷 76-81页
作者: WU Yun-pu QIAO Chuan-ling YANG Huan-liang CHEN Yan ZHAN Xiao-guo XIN Xiao-guang CHEN Hua-lan Animal Influenza Laboratory of the Ministry of Agriculture State Key Laboratory of Veterinary BiotechnologyHarbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150001China Liaoning Center for Animal Disease Control and Prevention Shenyang 110164China
To construct a recombinant adenovirus shuttle plasmid pDC315-H5HA-EGFP,the HA gene of A/Swine/Fujian/1/2001(H5N1) was amplified by RT-PCR and then inserted into adenovirus shuttle plasmid pDC315.A replication-defectiv... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
A primary study on the efficacy and safety of vascular endothelial growth factor’s gene therapy on the rat model of cerebral ischemic reperfusion via recombinant adenovirus
A primary study on the efficacy and safety of vascular endot...
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中国神经科学学会第四次会员代表大会暨第七届全国学术会议
作者: Long XU~1,Shi-Fang LI~2,Gui-Lin LI~2,Ren-Zhi WANG~2,Ji-Zong ZHAO~1 1 Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China 2 Department of Neurosurgery,Peking Union Medical College Hospital,Peking Union Medical College,Beijing 100730,China
<正>Cerebral infarction is a common and frequently encountered disease,which is mostly onset in people after middle age.For its severe complications and high ratios of disability and mortality,peoples’ health and l... 详细信息
来源: cnki会议 评论