检索结果-南通市图书馆

In vitro and in vivo antioxidant activities of three major polyphenolic compounds in pomegranate peel: Ellagic acid, punicalin, and punicalagin

引用

Journal of Integrative Agriculture 2017年第8期16卷 1808-1818页

作者： SUN Yu-qing TAO Xin MEN Xiao-ming XU Zi-wei WANG Tian College of Animal Science & Technology Nanjing Agricultural University Institute of Animal Husbandry and Veterinary Science Zhejiang Academy of Agricultural Sciences

Pomegranates is abundant in polyphenols and is well-known for its antioxidant activity. Punicalagin （PG） is a major poly- phenolic compound in the pomegranate peel. In certain conditions, PG can be hydrolyzed to punicallin （PL） and ellagic acid （EA）, and PL can be further hydrolyzed to EA. PG, PL, and EA all play important roles in the antioxidant activity of pomegranate peels. This study was conducted to compare the in vitro antioxidant activity and in vivo anti-oxidative stress effects of PG, PL, and EA. For the in vitro test, 2,2-diphenyl-l-picrylhydrazyl radical （DPPH.） and superoxide anion （O2~） scavenging capacities, ferric-reducing antioxidant power （FRAP）, and lipid peroxidation （LPO） inhibition capacities of PG, PL, and EA were tested. For the in vivo test, oxidatively stressed mice, which were induced by oxidized fish oil, were administrated PG, PL or EA （10 mg kg-1 d-1） for 21 days. The results showed that the in vitro antioxidant activity trends were EA〉PG〉PL〉Trolox in scavenging DPPH., PG〉PL〉EA=Trolox in scavenging O2~, EA〉PG=PL〉Trolox in FRAP, and Trolox〉PG〉EA〉PL in LPO inhibition. In the in vivo test, the EAt＇reatment increased the average daily weight gain and total antioxidant capacity （T-AOC） in the plasma （P〈0.05）, liver （P〈0.05）, and intestine （P〈0.05） in oxidatively stressed mice. It increased the superoxide dismutase （SOD） activity in the liver （P〈0.05） and intestine （P〈0.05）. It increased the glutathi- one peroxidase （GSH-Px） activity in the intestine （P〈0.05） and the intestinal villus height to crypt depth ratio （P〈0.05）. EA treatment decreased the malondialdehyde （MDA） content in the plasma （P〈0.05）, liver （P〈0.05）, and intestine （P〈0.05） and the mRNA expressions of the pro-inflammatory factors, TNF-a （P〈0.05）, IFN-y （P〈0.05） and IL-6 （P〈0.05）. PL increased the SOD （P〈0.05） and GSH-Px activities （P〈0.05） in the intestine and decreased the MDA content （P〈0.05） and the mRNA expressions of TNF-a （P〈0.05） and IL-6 （P〈0.05） in the intestine. PG i

关键词： ellagic acid punicalin punicalagin antioxidant oxidative stress

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Punicalagin和punicalin抗氧化和对扑热息痛诱导大鼠肝损伤的保护作用

引用

国际中医中药杂志 2002年第2期24卷 105-106页

作者：左风

Punicalagin(PCG)和punicalin(PC)是从植物榄仁树(Terminalia catappa)中分离出的2种化合物。此种植物在东南亚地区主要用于治疗皮炎和肝炎。研究发现其叶具有抗氧化、抗炎、保肝以及抗HIV复制的作用。叶中主要成分有PCG、PC、诃子酸和... 详细信息

Punicalagin(PCG)和punicalin(PC)是从植物榄仁树(Terminalia catappa)中分离出的2种化合物。此种植物在东南亚地区主要用于治疗皮炎和肝炎。研究发现其叶具有抗氧化、抗炎、保肝以及抗HIV复制的作用。叶中主要成分有PCG、PC、诃子酸和鞣云实精等,而其中PCG、PC含

关键词：大鼠抗氧化活性扑热息痛醋氨酚 punicalin Punicalagin

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Punica granatum果实皮甲醇提取物化学成分的分离和标准化(英文)

引用

中国天然药物 2011年第6期9卷 414-420页

作者： Vishal Jain Murugananthan G Deepak M GL Viswanatha D Manohar Department of Pharmacognosy PES College of Pharmacy Department of Phytochemistry Natural Remedies Pvt Ltd. Department of Pharmacology PES College of Pharmacy

AIM:The present study was undertaken to isolate and standardize the various active phytochemical constituents present in the fruit rinds of Punica ***:Fruit rinds of Punica granatum were dried and extracted with methanol in a static extractor;the percentage yield of the methanolic extract (MEPG) was found to be 26%;the methanolic extract was partitioned using n-butanol,ethyl acetate and water;the percentage yield of the fractions were found to be 17.16%,26.88% and 47.72% *** was carried out for all the fractions and the markers corresponding to the major peaks in HPLC were isolated using column *** isolated markers were characterized using UV,IR,Mass and NMR *** & CONCLUSION:Totally four compounds were isolated and identified as punicalin,punicalagin,gallic acid and ellagic acid based on UV,IR,Mass and NMR data,they were standardized by HPLC.

关键词： Punica granatum punicalin Punicalagin Gallic acid and ellagic acid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：