Punica granatum果实皮甲醇提取物化学成分的分离和标准化(英文)

作     者：Vishal Jain Murugananthan G Deepak M GL Viswanatha D Manohar 

作者机构：Department of PharmacognosyPES College of Pharmacy Department of PhytochemistryNatural Remedies Pvt Ltd. Department of PharmacologyPES College of Pharmacy 

出 版 物：《中国天然药物》 (Chin. J. Nat. Med.)

年 卷 期：2011年第9卷第6期

页      面：414-420页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Punica granatum Punicalin Punicalagin Gallic acid and ellagic acid 

摘      要：AIM:The present study was undertaken to isolate and standardize the various active phytochemical constituents present in the fruit rinds of Punica ***:Fruit rinds of Punica granatum were dried and extracted with methanol in a static extractor;the percentage yield of the methanolic extract (MEPG) was found to be 26%;the methanolic extract was partitioned using n-butanol,ethyl acetate and water;the percentage yield of the fractions were found to be 17.16%,26.88% and 47.72% *** was carried out for all the fractions and the markers corresponding to the major peaks in HPLC were isolated using column *** isolated markers were characterized using UV,IR,Mass and NMR *** & CONCLUSION:Totally four compounds were isolated and identified as punicalin,punicalagin,gallic acid and ellagic acid based on UV,IR,Mass and NMR data,they were standardized by HPLC.