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psychotic symptoms in bipolar disorder and their impact on the illness:A systematic review

World Journal of Psychiatry 2022年第9期12卷 1204-1232页

作者： Subho Chakrabarti Navdeep Singh Department of Psychiatry Postgraduate Institute of Medical Education and ResearchChandigarh 160012UTIndia

BACKGROUND Lifetime psychotic symptoms are present in over half of the patients with bipolar disorder(BD)and can have an adverse effect on its course,outcome,and ***,despite a considerable amount of research,the impact of psychotic symptoms on BD remains unclear,and there are very few systematic reviews on the *** To examine the extent of psychotic symptoms in BD and their impact on several aspects of the *** The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were *** electronic literature search of six English-language databases and a manual search was undertaken to identify published articles on psychotic symptoms in BD from January 1940 to December *** of the relevant Medical Subject Headings terms were used to search for these *** were selected after a screening phase,followed by a review of the full texts of the *** of the methodological quality of the studies and the risk of bias was conducted using standard *** This systematic review included 339 studies of patients with *** psychosis was found in more than a half to two-thirds of the patients,while current psychosis was found in a little less than half of *** were more common than hallucinations in all phases of *** a third of the patients reported first-rank symptoms or mood-incongruent psychotic symptoms,particularly during manic *** symptoms were more frequent in bipolar type I compared to bipolar type II disorder and in mania or mixed episodes compared to bipolar *** psychotic symptoms were not more severe in BD,the severity of the illness in psychotic BD was consistently *** was usually associated with poor insight and a higher frequency of agitation,anxiety,and hostility but not with psychiatric *** was consistently linked with increased rates and the duration of hospitalizations,switching amo

关键词： psychotic symptoms Bipolar disorder Extent Impact

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