Psychotic symptoms in bipolar disorder and their impact on the illness:A systematic review
作者机构:Department of PsychiatryPostgraduate Institute of Medical Education and ResearchChandigarh 160012UTIndia
出 版 物:《World Journal of Psychiatry》 (世界精神病学杂志)
年 卷 期:2022年第12卷第9期
页 面:1204-1232页
核心收录:
学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
主 题:Psychotic symptoms Bipolar disorder Extent Impact
摘 要:BACKGROUND Lifetime psychotic symptoms are present in over half of the patients with bipolar disorder(BD)and can have an adverse effect on its course,outcome,and ***,despite a considerable amount of research,the impact of psychotic symptoms on BD remains unclear,and there are very few systematic reviews on the *** To examine the extent of psychotic symptoms in BD and their impact on several aspects of the *** The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were *** electronic literature search of six English-language databases and a manual search was undertaken to identify published articles on psychotic symptoms in BD from January 1940 to December *** of the relevant Medical Subject Headings terms were used to search for these *** were selected after a screening phase,followed by a review of the full texts of the *** of the methodological quality of the studies and the risk of bias was conducted using standard *** This systematic review included 339 studies of patients with *** psychosis was found in more than a half to two-thirds of the patients,while current psychosis was found in a little less than half of *** were more common than hallucinations in all phases of *** a third of the patients reported first-rank symptoms or mood-incongruent psychotic symptoms,particularly during manic *** symptoms were more frequent in bipolar type I compared to bipolar type II disorder and in mania or mixed episodes compared to bipolar *** psychotic symptoms were not more severe in BD,the severity of the illness in psychotic BD was consistently *** was usually associated with poor insight and a higher frequency of agitation,anxiety,and hostility but not with psychiatric *** was consistently linked with increased rates and the duration of hospitalizations,switching amo