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第十三届江浙沪儿科学术会议暨2016年浙江省医学会儿科学学术年会

作者： Zengyou Jin Hongying Shi Huixian Qiu Niannian Huang Lianhong Jia Jiacheng Lu Zhimin Geng Lulu Pan Rongzhou Wu Maoping Chu Department of Pediatrics the First Affiliated Hospital of Wenzhou Medical University Department of preventive medicine School of Environmental Science and Public HealthWenzhou Medical University Children's Heart Center the Second Affiliated Hospital & Yuying Children's HospitalInstitute of cardiovascular development and translational medicineWenzhou Medical University

Background:Kawasaki disease(KD) is the leading cause of the acquired heart disease in children,which predominantly affects coronary *** short-term,small sample studies suggest thatyoung infants might be susceptible to developing coronary artery lesion(CAL) than older ones,although the mechanism remains *** study was to identify the clinical features and coronary artery outcomes in a 5-years follow-up period among1135 patients of KD with different ***:The clinical features and echocardiography of coronary artery lesions of KD patients in the follow-up period were *** Cox regression analysis was used to screen out the independent risk factors for the development of coronary artery ***:During the follow-up,the rate of new developed CAL in the 60 months age *** CAL incidence in the 60 months age groups after intravenous immunoglobulin(IVIG) treatment during follow-up *** CAL recover among three age groups,who had CAL before treatment,was ***,incomplete KD,IVIG method,IVIG-nonresponse and hypoalbuminemia were also identified as independent prognostic factors for CAL development in addition to ***:This large sample,long-term follow-up study demonstrates that the KD patient younger than 12 months is a high risk population of CAL,even after *** Results remind us to pay more attention to these high risk KD patients who may need a more active therapy.

关键词： Kawasaki disease coronary artery age clinical features prognostic factor

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A real-world study of nimotuzumab treatment in combination with radiotherapy concurrently with or without chemotherapy for patients with oral and maxillofacial tumors

A real-world study of nimotuzumab treatment in combination w...

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2019第一届全国口腔颌面-头颈肿瘤学术大会——聚合引领、协同发展

作者：劳峥涂文勇上海交通大学医学院附属第九人民医院

Purpose/Background:This study aimed to evaluate the safety and efficacy of nimotuzumab from the realworld practice of nimotuzumab treatment in combination with intensity-modulated radiotherapy(IMRT) with or without ch... 详细信息

关键词： nimotuzumab intensity-modulated radiotherapy chemotherapy overall survival prognostic factor side effect

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A Research on factors Influencing the Clinical Prognosis of Acute Stroke ***

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中国临床神经科学 2000年第Z1期8卷 68-页

作者： Luo Zuming Li Manli Dept. Of Neurology the First Teaching Hospital West China University of medical Sciences Chengdu Sichuan 610041 P.R.China Dept. Of Neurology the First Teaching Hospital West China University of medical Sciences Chengdu Sichuan 610041 P.R.China

Object: To search for the factors significantly influencing the clinical prognosis of acute stroke patients. Background: There are lack of prospective multivariate analysis research m acute stroke in the world. Method: We chose 17 factors possibly influencing the prognosis of acute patients, took Barthel′s Index at the end of 2 months after stroke onset and decreased percentage of neurological deficit scores (MESSS) between 72h after hospitalization and 2 months after onset as gold standard, to have a prospective, multivariate analysis research combined with univariate analysis. Results: Multivariate analysis of 106 acute stroke patients combined with univariate analysis showed the factors significantly influencing the clinical prognosis of acute stroke patients were: initial MESSS score、 age、 complication、 mass effect、 stroke location、 time of delay before emergency arrival (BDT). Time of delay after emergency arrival was not found to be a significant prognostic factor. Discussion: Barthel Index at the end of 1 month after stroke onset was strongly related to that at the end of 2 month after onset, as was the same with MESSS score. It showed there was no significant difference between 1 month and 2 months after stroke onset when we choose time interval in evaluating prognosis of acute stroke ***: BDT、 initial MESSS score、 age、 stroke location、 mass effect、 complication were important factors of acute stroke patients. Avoid the delay before emergency arrival after onset, prevent and treat complications after stroke, more carefully treat acute stroke patients with advanced age, advanced age, high initial MESSS scores and those with mass effect reported by CT, we can improve the outcome of stroke patients.

关键词： acute stroke multivariate analysis mass effect prognostic factor the world

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The significance and clinical utility of the detection of primary malignant circulating prostate cells:a review of the evidence

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Journal of Cancer Metastasis and Treatment 2016年第1期2卷 453-462页

作者： Nigel P.Murray Hospital Carabineros of Chile Nunoa7770199 SantiagoChile Faculty of Medicine University Finis TerraeProvidencia7501015 SantiagoChile

Primary malignant circulating prostate cells(CPCs)are those detected in blood before definitive treatment for prostate *** can be detected in men with benign prostate disease;however,some methods to distinguish between benign and malignant prostate cells have to be *** study presents a review of the subject,including theoretical considerations for the selection of markers to detect them,the different methods used,and the utility of their detection in identifying men with prostate cancer and as a prognostic factor.

关键词： Prostate cancer circulating prostate cells cancer detection prognostic factor

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Optimal treatment for Siewert type Ⅱ and Ⅲ adenocarcinoma of the esophagogastric junction: A retrospective cohort study with long-term follow-up

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World Journal of Gastroenterology 2017年第15期23卷 2723-2730页

作者： Kei Hosoda Keishi Yamashita Hiromitsu Moriya Hiroaki Mieno Masahiko Watanabe Department of Surgery Kitasato University School of Medicine

AIM To determine the optimal treatment strategy for Siewert type Ⅱ and?Ⅲ?adenocarcinoma of the esophagogastric *** We retrospectively reviewed the medical records of 83 patients with Siewert type?Ⅱ?and?Ⅲ?adenocarcinoma of the esophagogastric junction and calculated both an index of estimated benefit from lymph node dissection for each lymph node(LN) station and a lymph node ratio(LNR: ratio of number of positive lymph nodes to the total number of dissected lymph nodes). We used Cox proportional hazard models to clarify independent poor prognostic factors. The median duration of observation was 73 *** Indices of estimated benefit from LN dissection were as follows, in descending order: lymph nodes(LN) along the lesser curvature, 26.5; right paracardial LN, 22.8; left paracardial LN, 11.6; LN along the left gastric artery, 10.6. The 5-year overall survival(OS) rate was 58%. Cox regression analysis revealed that vigorous venous invasion(v2, v3)(HR = 5.99; 95%CI: 1.71-24.90) and LNR of > 0.16(HR = 4.29, 95%CI: 1.79-10.89) were independent poor prognostic factors for *** LN along the lesser curvature, right and left paracardial LN, and LN along the left gastric artery should be dissected in patients with Siewert type?Ⅱ?or?Ⅲ?adenoca rcinoma of the esophagogastric junction. Patients with vigorous venous invasion and LNR of > 0.16 should be treated with aggressive adjuvant chemotherapy to improve survival outcomes.

关键词： Adenocarcinoma of the esophagogastric junction Lymph node ratio Venous invasion Lymph node dissection prognostic factor

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