A long-term follow-up study on clinical features and coronary artery outcomes of different age patients with Kawasaki disease
作者单位：Department of Pediatricsthe First Affiliated Hospital of Wenzhou Medical University Department of preventive medicineSchool of Environmental Science and Public HealthWenzhou Medical University Children's Heart Centerthe Second Affiliated Hospital & Yuying Children's HospitalInstitute of cardiovascular development and translational medicineWenzhou Medical University
会议名称：《第十三届江浙沪儿科学术会议暨2016年浙江省医学会儿科学学术年会》
会议日期：2016年
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
关 键 词：Kawasaki disease coronary artery age clinical features prognostic factor
摘 要：Background:Kawasaki disease(KD) is the leading cause of the acquired heart disease in children,which predominantly affects coronary *** short-term,small sample studies suggest thatyoung infants might be susceptible to developing coronary artery lesion(CAL) than older ones,although the mechanism remains *** study was to identify the clinical features and coronary artery outcomes in a 5-years follow-up period among1135 patients of KD with different ***:The clinical features and echocardiography of coronary artery lesions of KD patients in the follow-up period were *** Cox regression analysis was used to screen out the independent risk factors for the development of coronary artery ***:During the follow-up,the rate of new developed CAL in the 60 months age *** CAL incidence in the 60 months age groups after intravenous immunoglobulin(IVIG) treatment during follow-up *** CAL recover among three age groups,who had CAL before treatment,was ***,incomplete KD,IVIG method,IVIG-nonresponse and hypoalbuminemia were also identified as independent prognostic factors for CAL development in addition to ***:This large sample,long-term follow-up study demonstrates that the KD patient younger than 12 months is a high risk population of CAL,even after *** Results remind us to pay more attention to these high risk KD patients who may need a more active therapy.