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Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis

World Journal of Clinical Cases 2021年第35期9卷 10899-10908页

作者： Xian-Qiang Yu Hong-Bin Deng Yang Liu Cheng Qu Ze-Hua Duan Zhi-Hui Tong Yu-Xiu Liu Wei-Qin Li Medical School Southeast UniversityNanjing 210009Jiangsu ProvinceChina Department of Critical Care Medicine Nanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care Medicine Nanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Critical Care Medicine General Hospital of Eastern Theater CommandNanjing 210002Jiangsu ProvinceChina

BACKGROUND Decreased serum magnesium(Mg2+)is commonly seen in critically ill *** is significantly more frequent in patients with severe acute *** kidney injury(AKI)in patients with acute pancreatitis(AP)is associated with an extremely high *** association underlying serum Mg2+and AKI in AP has not been *** To explore the association between serum Mg2+on admission and AKI in patients with *** A retrospective observational study was conducted in a cohort of patients(n=233)with AP without any renal injury before admission to our center from August 2015 to February *** characteristics on admission,severity score,laboratory values and in-hospital mortality were compared between patients with and without *** A total of 233 patients were included for analysis,including 85 with *** to patients without AKI,serum Mg2+level was significantly lower in patients with AKI at admission[OR=6.070,95%CI:3.374-10.921,P<0.001].Multivariate logistic analysis showed that lower serum Mg2+was an independent risk factor for AKI[OR=8.47,95%CI:3.02-23.72,P<0.001].CONCLUSION Our analysis indicates that serum Mg2+level at admission is independently associated with the development of AKI in patients with AP and may be a potential prognostic factor.

关键词： acute pancreatitis acute kidney injury Magnesium(Mg2+) kidney predictor of acute kidney injury

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