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precision surgery for Placenta Previa Complicated with Placenta Percreta

Maternal-Fetal Medicine 2019年第1期1卷 18-24页

作者： Juan-Juan Chen Lin Yu Chun-Hong Su Chun-Fang Zhang Yan-Hong Chen Yan-Mei Zhou Wen-Jun He Fang He Ting Song Shou-Ping Wang Zhi-Yuan Su Qing-Ping Jiang Zi-Hao Zou Bin Yu Xiao-Ya Shen Xiao-Ming Guan Dun-Jin Chen Key Laboratory for Major Obstetric Diseases of Guangdong Province Department of Gynaecology andObstetricsThird Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong510150China Department of Radiology Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Anesthesiology Third Affiliated Hospital ofGuangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Pathology ThirdAffiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong510150China Department of Urology Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510150China Department of Obstetrics&Gynecology Baylor College ofMedicineHoustonUSA

Objectives:To investigate whether a precise circular resection of the uterine tissue at the placental attachment part is effective in cases with placenta previa complicated with placenta percreta (PPWPP).Methods:Patients diagnosed with PPWPP were assessed for pregnancy termination at 34-36 weeks of *** the operation,we performed circular resection of the uterine tissue at the placental attachment *** the characteristics of the operation and the follow-ups were ***:During the operation,the vital signs were *** mean intraoperative blood loss,packed red blood cells units transfusion,fresh frozen plasma transfusion,and operation time were 2140 mL,6 U,440 mL,and 179.8 minutes,*** was no bowel,ureter,or bladder *** there was no patient transferred to the ICU after *** mean postoperative blood loss was *** was no fever,infection,intestinal obstruction,or other complications after operation during the *** shape and the blood flow of the uterus were *** the patients were discharged,one had developed cesarean scar *** mean lochia duration was 30 *** menstrual cycle and volume were as *** shape and the blood flow of the uterus and the ovarian were ***:The circular resection following end-to-end anastomosis is an effective precision surgical approach for *** can achieve the purpose of hemostasis while maximizing the protection of organ function and reducing surgical trauma.

关键词： Placenta previa Placenta percreta precision surgery Circular resection

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precision medicine for gastrointestinal cancer:Recent progress and future perspective

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World Journal of Gastrointestinal Oncology 2020年第1期12卷 1-20页

作者： Tasuku Matsuoka Masakazu Yashiro Department of Gastroenterological surgery Osaka City University Graduate School of MedicineOsaka 5458585Japan Oncology Institute of Geriatrics and Medical Science Osaka City University Graduate School of MedicineOsaka 5458585Japan

Gastrointestinal(GI)cancer has a high tumor incidence and mortality rate *** significant improvements in radiotherapy,chemotherapy,and targeted therapy for GI cancer over the last decade,GI cancer is characterized by high recurrence rates and a dismal *** is an urgent need for new diagnostic and therapeutic *** technological advances and the accumulation of clinical data are moving toward the use of precision medicine in GI *** we review the application and status of precision medicine in GI *** of liquid biopsy specimens provide comprehensive real-time data of the tumor-associated changes in an individual GI cancer patient with *** the introduction of gene panels including next-generation sequencing,it has become possible to identify a variety of mutations and genetic biomarkers in GI *** the genomic aberration of GI cancer is apparently less actionable compared to other solid tumors,novel informative analyses derived from comprehensive gene profiling may lead to the discovery of precise molecular targeted *** progressions will make it feasible to incorporate clinical,genome-based,and phenotype-based diagnostic and therapeutic approaches and apply them to individual GI cancer patients for precision medicine.

关键词： Gastrointestinal cancer Esophageal cancer Gastric cancer Colorectal cancer precision medicine Liquid biopsy Gene panel precision surgery Biomarkers

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