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Effect of Post-ERCP Pancreatitis on Perioperative Factors of Pancreaticoduodenectomy

Surgical Science 2015年第2期6卷 35-41页

作者： Teijiro Hirashita Toshifumi Matsumoto Koichi Izumi Masahiko Ikebe Tokujiro Yano Yoichi Muto Susumu Matsuo Department of Surgery National Hospital Organization Beppu Medical Center Beppu Japan Department of Gastroenterology National Hospital Organization Beppu Medical Center Beppu Japan

Background:?Endoscopic retrograde cholangiopancreatography (ercp) is commonly performed for biliary drainage and examination of the biliary and pancreatic duct before pancreaticoduodenectomy (PD). The influence of preoperative Post-ERCP pancreatitis on PD is unknown. The aim of this study was to evaluate the relation between Post-ERCP pancreatitis before PD and surgical outcomes of PD. Methods: We examined 38 patients who underwent PD. The relations between Post-ERCP pancreatitis before PD and perioperative factors of PD such as patient characteristics, operative findings, and postoperative course were evaluated with univariate and multivariate analyses. Results: Post-ERCP pancreatitis was observed in 12 (37.5%) of the 38 patients. Univariate analyses showed operative procedure (P?= 0.034), operation time (P?= 0.004), blood loss (P?= 0.031), C-reactive protein (P?= 0.043), and delayed gastric emptying (P?= 0.035) to be significantly associated with Post-ERCP pancreatitis. Multivariate analyses showed operation time (OR, 1.017;?95%CI, 1.000 - 1.034;?P?= 0.049) and delayed gastric emptying (OR, 18.72;95%CI, 1.139 - 307.6;?P?= 0.040) to be significantly associated with Post-ERCP pancreatitis. Conclusions: Post-ERCP pancreatitis was associated with prolonged operation time and delayed gastric emptying in patients undergoing PD.

关键词： Endoscopic Retrograde Cholangiopancreatography Post-ERCP Pancreatitis Pancreaticoduodenectomy

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Prophylactic Effect of Somatostatin on Post-ERCP Pancreatitis： A Randomized Controlled Trial

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胃肠病学 2000年第B8期5卷 145-145页

作者： SongJun LiuJun LiuShi HouXiao-hua YiCui-qiong Dept.ofGastroenterology UnionHospitalWuhan430022China

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Safety and Feasibility of Oral Rehydration Solution Prior to Endoscopic Retrograde Cholangiopancreatography

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Surgical Science 2015年第3期6卷 91-99页

作者： Takamitsu Sasaki Daisuke Kato Ryohei Sakamoto Satoshi Shinya Hironari Shiwaku Kanefumi Yamashita Ryo Nakashima Yuichi Yamashita Department of Gastroenterological Surgery Fukuoka University School of Medicine Fukuoka Japan

Purpose: The safety of oral rehydration therapy before endoscopic screening with respect to vital signs and complications after the screening procedure was assessed in patients undergoing endoscopic retrograde cholangiopancreatography (ercp). Methods: A total of 107 patients scheduled for ercp were assigned to either the intravenous drip injection (DIV) group during fasting (56 patients) or ORS group given oral rehydration solution (51 patients) prior to endoscopy. Vital signs after ercp, including blood pressure and temperature, blood biochemical data and the incidence of Post-ERCP complications were compared between the groups. Results: No cases of aspiration pneumonia were detected in either groups. Moreover, there were no statistically significant differences between the DIV group and ORS group in terms of the biochemical data and vital signs after ercp. The intergroup difference in the development of pancreatitis after ercp was 2.3% [95% CI: ?5.7, 10.3], which was not statistically significant. Conclusions: The safety of oral rehydration therapy was found to be equivalent to that of the customary practice of infusion as a method for managing hydration and replenishing electrolytes in patients receiving ercp. Oral rehydration therapy may be easily utilized as rehydration therapy prior to endoscopic screening for ercp and other procedures.

关键词： Endoscopic Retrograde Cholangiopancreatography Oral Rehydration Therapy Oral Rehydration Solution Post-ERCP Pancreatitis Complication

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