Effect of Post-ERCP Pancreatitis on Perioperative Factors of Pancreaticoduodenectomy
Effect of Post-ERCP Pancreatitis on Perioperative Factors of Pancreaticoduodenectomy作者机构：Department of Surgery National Hospital Organization Beppu Medical Center Beppu Japan Department of Gastroenterology National Hospital Organization Beppu Medical Center Beppu Japan
出 版 物：《Surgical Science》 (外科学（英文）)
年 卷 期：2015年第6卷第2期
页 面：35-41页
主 题：Endoscopic Retrograde Cholangiopancreatography Post-ERCP Pancreatitis Pancreaticoduodenectomy
摘 要：Background:?Endoscopic retrograde cholangiopancreatography (ERCP) is commonly performed for biliary drainage and examination of the biliary and pancreatic duct before pancreaticoduodenectomy (PD). The influence of preoperative post-ERCP pancreatitis on PD is unknown. The aim of this study was to evaluate the relation between post-ERCP pancreatitis before PD and surgical outcomes of PD. Methods: We examined 38 patients who underwent PD. The relations between post-ERCP pancreatitis before PD and perioperative factors of PD such as patient characteristics, operative findings, and postoperative course were evaluated with univariate and multivariate analyses. Results: Post-ERCP pancreatitis was observed in 12 (37.5%) of the 38 patients. Univariate analyses showed operative procedure (P?= 0.034), operation time (P?= 0.004), blood loss (P?= 0.031), C-reactive protein (P?= 0.043), and delayed gastric emptying (P?= 0.035) to be significantly associated with post-ERCP pancreatitis. Multivariate analyses showed operation time (OR, 1.017;?95%CI, 1.000 - 1.034;?P?= 0.049) and delayed gastric emptying (OR, 18.72;95%CI, 1.139 - 307.6;?P?= 0.040) to be significantly associated with post-ERCP pancreatitis. Conclusions: Post-ERCP pancreatitis was associated with prolonged operation time and delayed gastric emptying in patients undergoing PD.
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