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Comparison of total splenic artery embolization and partial splenic embolization for hypersplenism

World Journal of Gastroenterology 2012年第24期18卷 3138-3144页

作者： Xin-Hong He Jian-Jian Gu Wen-Tao Li Wei-Jun Peng Guo-Dong Li Sheng-Ping Wang Li-Chao Xu Jun Ji Department of Radiology Cancer Hospital/Cancer Institute Shanghai Medical CollegeFudan University Shanghai 200032 China Department of Oncology People's Hos-pital of Tongzhou District Nantong 226300 Jiangsu ProvinceChina

AIM:To evaluate whether total splenic artery embolization(TSAE) for patients with hypersplenism delivers better long-term outcomes than partial splenic embolization(PSE).METHODS:Sixty-one patients with hypersplenism eligible for TSAE(n = 27,group A) or PSE(n = 34,group B) were enrolled into the trial,which included clinical and computed tomography *** on technical success,length of hospital stay,white blood cell(WBC) and platelet(PLT) counts,splenic volume and complications were collected at 2 wk,6 mo,and 1,2,3,4 years ***:Both TSAE and PSE were technically successful in all *** were significantly fewer(P = 0.001),and hospital stay significantly shorter(P = 0.007),in group A than in group *** WBC and PLT counts in group A were significantly higher than those in group B from 6 mo to 4 years(P = 0.001),and post-procedure residual splenic volume in group A was significantly less than that observed in group B at 1,2,3 and 4 years post-procedure(P = 0.001).No significant differences were observed in red blood cell counts and liver function parameters between the two groups following the ***:Our results indicate that TSAE for patients with hypersplenism not only delivers a better longterm outcome,but is also associated with lower complication rates and a shorter hospital stay than PSE.

关键词： Embolization Hypersplenism Complications White cell counts platelet counts

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Helicobacter pylori eradication in patients with chronic immune thrombocytopenic purpura

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World Journal of Gastroenterology 2014年第22期20卷 6918-6923页

作者： Ravinder Naik Noonavath Chandrasekharan Padma Lakshmi Tarun Kumar Dutta Vikram Kate Department of Surgery Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherry 605006India Department of Medical Gastroenterology Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherry 605006India Department of Clinical Hematology Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherry 605006India Department of General and Gastrointestinal Surgery Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherry 605006India

AIM: To assess the effect of Helicobacter pylori (H. pylori) eradication on platelet counts in patients with chronic immune thrombocytopenic purpura (cITP).

关键词： Helicobacter pylori Immune thrombocytopenic purpura platelet counts

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Predictive value of thrombocytopenia for bloodstream infection in patients with sepsis and septic shock

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World Journal of Critical Care Medicine 2024年第1期13卷 49-57页

作者： Xia Li Sheng Wang Jun Ma Su-Ge Bai Su-Zhen Fu Department of Critical Care Medicine Xingtai People HospitalXingtai 054001Hebei ProvinceChina Department of Physiology Hebei Collaborative Innovation Center for Cardiocerebrovascular DiseaseHebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Thrombocytopenia is common in patients with sepsis and septic *** To analyse the decrease in the number of platelets for predicting bloodstream infection in patients with sepsis and septic shock in the intensive care *** A retrospective analysis of patients admitted with sepsis and septic shock in Xingtai People Hospital was *** population characteristics and laboratory data were collected for *** The study group consisted of 85(39%)inpatients with bloodstream infection,and the control group consisted of 133(61%)with negative results or *** percentage decline in platelet counts(PPCs)in patients positive for pathogens[57.1(41.3-74.6)]was distinctly higher than that in the control group[18.2(5.1–43.1)](Pplatelet drop rate was 0.839(95%CI:0.783-0.895).CONCLUSION The percentage decline in platelet counts is sensitive in predicting bloodstream infection in patients with sepsis and septic ***,it cannot identify gram-positive bacteraemia,gram-negative bacteraemia,and fungal infection.

关键词： platelet counts Thrombocytopenia Bloodstream infection Sepsis Shock

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