Predictive value of thrombocytopenia for bloodstream infection in patients with sepsis and septic shock

作     者：Xia Li Sheng Wang Jun Ma Su-Ge Bai Su-Zhen Fu 

作者机构：Department of Critical Care MedicineXingtai People HospitalXingtai 054001Hebei ProvinceChina Department of PhysiologyHebei Collaborative Innovation Center for Cardiocerebrovascular DiseaseHebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina 

出 版 物：《World Journal of Critical Care Medicine》 (世界重症医学杂志)

年 卷 期：2024年第13卷第1期

页      面：49-57页

学科分类：100218[医学-急诊医学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Platelet counts Thrombocytopenia Bloodstream infection Sepsis Shock 

摘      要：BACKGROUND Thrombocytopenia is common in patients with sepsis and septic *** To analyse the decrease in the number of platelets for predicting bloodstream infection in patients with sepsis and septic shock in the intensive care *** A retrospective analysis of patients admitted with sepsis and septic shock in Xingtai People Hospital was *** population characteristics and laboratory data were collected for *** The study group consisted of 85(39%)inpatients with bloodstream infection,and the control group consisted of 133(61%)with negative results or *** percentage decline in platelet counts(PPCs)in patients positive for pathogens[57.1(41.3-74.6)]was distinctly higher than that in the control group[18.2(5.1–43.1)](P0.001),whereas the PPCs were not significantly different among those with gram-positive bacteraemia,gram-negative bacteraemia,and fungal *** receiver operating characteristic curves,the area under the curve of the platelet drop rate was 0.839(95%CI:0.783-0.895).CONCLUSION The percentage decline in platelet counts is sensitive in predicting bloodstream infection in patients with sepsis and septic ***,it cannot identify gram-positive bacteraemia,gram-negative bacteraemia,and fungal infection.