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Effect of Acupressure Therapy on Anti-inflammatory Mechanism in obesity-induced IR Rats

Medicinal Plant 2023年第4期14卷 62-64页

作者： Xiaochao GANG Mingjun LIU Tianjiao GAO Yuxing TAI Yi TAN Dongmei ZHANG Chongwen ZHONG Shaotao CHEN Rongsheng JIANG Zhengri CONG Likun ZHENG Peizhe LI College of Acupuncture and Tuina Changchun University of Chinese MedicineChangchun 130117China

[Objectives] To study the effect of "acupressure therapy" on anti-inflammatory mechanism in obesity-induced IR rats. [Methods] 10 rats were randomly selected and fed with normal diet as blank group, and the remaining 30 rats were fed with high-fat diet for 8 weeks. The obesity-induced IR model was induced and divided into two groups: model group and acupressure group. The acupressure group was treated by "acupressure therapy" three times a week for 6 weeks;the model group was taken 3 times at the same time every week, and the supine binding experiment lasted for 10 min for 6 weeks. Morphological observation was carried out before and after the experiment, mainly observing the general conditions and body weight. After the last intervention, the animals were killed and samples were collected. Western Blot method was used to detect the expression of TNF-α and IL-6 protein in adipose tissue of the three groups. [Results] Compared with the blank group, the expression of TNF-α and IL-6 protein in adipose tissue of the model group increased significantly ( P obesity-induced IR rats with acupressure method, the status of insulin resistance in obese rats was improved by inhibiting the expression of inflammatory factors.

关键词： Massage Acupressure therapy obesity and insulin resistance Anti-inflammatory mechanism

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