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Massive Rhinorrhea as a Complication of COVID-19 nasopharyngeal swab

Open Journal of Modern Neurosurgery 2023年第3期13卷 145-148页

作者： Inas El Kacemi Yao Christian Hugues Dokponou Fresnel Lutèce Ontsi Obame Moussa Elmi Saad Napoleao Imbunhe Salami Mohcine Abad Cherif El Asri Miloud Gazzaz Department of Neurosurgery Military Teaching Hospital Mohammed V University Rabat Morocco

The nasopharyngeal swab for COVID-19 testing is generally considered safe;however, it is primarily performed by staff that may not completely understand the anatomy of the nasal cavity and nasopharynx. We report the treatment of a 48-year-old man who developed unilateral left rhinorrhea after a nasopharyngeal swab sample. It is aimed to draw attention to this complication that can be prevented with the appropriate technique during nasopharyngeal swab sampling.

关键词： COVID-19 Testing nasopharyngeal swab Rhinorrhea

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Virology features of a family cluster of SARS-CoV-2 infections in Shanghai,China

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Biosafety and Health 2021年第4期3卷 187-189页

作者： Yanqiu Zhou Zheng Teng Hongyou Chen Xiaoxian Cui Fanghao Fang Jiabin Mou Hui Jiang Xi Zhang Shanghai Municipal Center for Disease Control and Prevention Shanghai 200336China

The global spread of SARS-CoV-2 is currently continuing,and the World Health Organization has announced the risk assessment of the viruses as *** this study,we analyzed virology features of SARS-CoV-2 causing a family cluster *** the six family members,five have been laboratory-confirmed infection of SARS-CoV-2 viruses.A total of five SARS-CoV-2 viruses have been isolated from the nasopharyngeal *** complete genome of the viruses exhibited 100%nucleotide identity with each *** two nucleotide differences have been observed between genomes of the isolated viruses and the HCoV/Wuhan/IVDC-HB-01/2019 ***,SARS-CoV-2 has been confirmed as the causation of the family cluster infections.

关键词： SARS-CoV-2 Family cluster nasopharyngeal swab Full genome sequencing

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Efficacy of SARS-CoV-2 detection from used surgical masks compared with standard detection method

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Biosafety and Health 2024年第1期6卷 35-39页

作者： Uraporn Phumisantiphong Anan Manomaipiboon Yuttana Apichatbutr Kittisak Pholtawornkulchai Chunlanee Sangketchon Busaba Supawattanabodee Thananda Trakarnvanich Department of Clinical Pathology Faculty of MedicineVajira HospitalNavamindradhiraj UniversityBangkok 10300Thailand Department of Surgery Faculty of MedicineVajira HospitalNavamindradhiraj UniversityBangkok 10300Thailand Department of Medicine Faculty of MedicineVajira HospitalNavamindradhiraj UniversityBangkok 10300Thailand Department of Emergency Medical and Public Disaster Operations Faculty of Science and Health TechnologyNavamindradhiraj UniversityBangkok 10300Thailand Department of Research and Medical Innovation Faculty of MedicineVajira HospitalNavamindradhiraj UniversityBangkok 10300Thailand

The real‐time reverse transcription‐polymerase chain reaction(RT‐PCR)test is the gold standard for severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)*** specimen collection and obtaining a sufficient specimen are the most essential steps for laboratory *** nasopharyngeal(NP)swab is recommended as the reference collection ***,NP swab collection is invasive and uncomfortable for patients and poses some risk to healthcare *** study aimed to compare the efficacy of SARS‐CoV‐2 RNA detection from surgical masks with the NP swab method using RT‐PCR *** 269 patients,RT‐PCR RNA from NP swabs was detected among 82 patients(30.5%)and was undetected among 187 patients(69.5%).All patients were tested for SARS‐CoV‐2 RNA from surgical ***‐CoV‐2 RNA was detected in 25/82(30.5%)surgical mask filters,while undetected among 57(69.5%).For the surgical mask with an average use time of 7.05 h,the sensitivity was 30.5%,the specificity was 100.0%,with positive predictive value of 100.0%and negative predictive value of 76.2%.Therefore,surgical masks could be an alternative non‐invasive specimen source for SARS‐CoV‐2 RT‐PCR *** results of our study suggest that the test could be employed after wearing surgical masks for at least 8‐12 h,with increased sensitivity when used for more than 12 h.

关键词： nasopharyngeal swab RT‐PCR SARS‐CoV‐2 Surgical mask

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Evaluation of Rapid Detection of nasopharyngeal Colonization with MRSA by Real-Time PCR

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国际感染病学（电子版） 2012年第1期1卷 -页

作者： Feng-feng Kang Shu-yan Cao Yan-ming Li Jiang-tao Li Qing He Yi Li Yun-jian Hu Beijing Hospital Ministry of Health Institution of Laboratory Medicine Xiangya School of MedicineCentral South University

Objective To investigate the clinical application of Real-Time PCR for rapid detection of methicillin-resistant Staphylococcus aureus(MRSA) directly from nasopharyngeal swab *** We collected the nasal and throat swab specimens from patients or medical staffs in 3 intensive care units,blood laminar flow ward and respiratory ward in Beijing Hospital,Ministry of Health from December 2010to April *** sample was tested by RT-PCR and conventional culture-based method for the presence of *** The total number of the specimens was *** with the conventional culture-based method,we demonstrated the diagnostic values for Real-Time PCR were 96.4%sensitivity,96.6%specificity,81.8%positive predictive rate,and 99.4%negative predictive *** the limit of detection was 10~2CFU/*** This Real-Time PCR is a simple,rapid,sensitive and specific *** the high negative predictive value,it can be used for the exclusion of MRSA colonization or ***,the application of its low positive predictive value should be further evaluated.

关键词： Real-Time PCR MRSA nasopharyngeal swab

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