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mucinous carcinoma of the Scrotum about a Case in Yaounde

Open Journal of Urology 2023年第6期13卷 173-177页

作者： Boris Amougou Fred Dikongue Dikongue Divine Eyongeta Thierno Mamadou Oury Diallo David Douglas Banga Nkomo Demba Cisse Arlette Dongmo Alice Ghislaine Ndoumba Afouba Joseph Fondop Theodore Sala Beyeme Faustin Atemkeng Yaya Sow Abdoulaye Bobo Diallo Fru Angwafor Department of Surgery and Surgical Specialties Faculty of Medicine and Pharmaceutical Sciences University of Dschang Dschang Cameroon Department of Surgery and Surgical Specialties Faculty of Health Sciences of Buéa University Buéa Cameroon Faculty of Medicine and Pharmacy Gamal Abdel Nasser University Conakry Guinea Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Surgery and Surgical Specialties Faculty of Health Sciences of Gaston Berger University Saint-Louis Senegal Department of Surgery Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon

Aim: This paper aims to report the second case of mucinous carcinoma of the scrotum revealed by scrotal fistulas listed in the literature and highlight the difficulties in the search and difficulties encountered in the management of urogenital cancers in developing countries. Case presentation: This was a 62-year-old patient who had consulted for fistulized lesions of the scrotum associated with urinary disorders. Physical examination found budding lesions in the scrotum from which mucus was leaking. The diagnostic assessment carried out consisted of a biopsy sample of the scrotal lesions, a blood analysis and medical imaging, which led to the diagnosis. The mutilating nature of the surgery proposed to the patient after multidisciplinary consultation meeting and the expensive cost of chemotherapy drugs constituted the limits of the patient’s therapeutic management. Conclusion: mucinous carcinoma of the scrotum is rare and primary lesion should always be sought. The presence of budding lesions of the scrotum with discharge of mucus should suggest the diagnosis.

关键词： Scrotal Cancer mucinous carcinoma Scrotal Fistulas

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Primary mucinous carcinoma of the thyroid: case report and review of the literature

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Cancer Advances 2022年第23期5卷 1-4页

作者： Neng-Liang Zhang Jian-Hua Wang Wei Cheng Zheng-Jing Li Jie Tang Tao Wang Yi Chen Clinical Medical College of Dali University Dali 671000China Department of Oncology The First Affiliated Hospital of Dali UniversityDali 671000China Department of Surgery The First Affiliated Hospital of Dali UniversityDali 671000China

Primary mucinous carcinoma of the thyroid gland which is more difficult to diagnose than common thyroid cancer is an extremely rare *** is a malignant tumor that can secrete mucus.A 45-year-old Chinese man came to seek medical care because he found a lump in his right *** showed that there was a space-occupying lesion on the right thyroid gland which compressed the *** the operation of total thyroidectomy and lymph node dissection in the right central area,the pathological examination showed that tumor cells existed,showing a small nest-like and cribriform distribution *** were broad fibrous tissues,a large amount of mucus around the tumur cell that had no obvious amyloid *** tumor cells were positive for thyroid transcription factor-1 and paired box gene-8,while they were focally positive for *** the histological features and immunohistochemical profile and ruling out mucinous cancers originating from other *** patient was diagnosed with primary mucinous carcinoma of the thyroid *** patient is still alive at *** of primary mucinous carcinoma of the thyroid gland is usually *** best way to improve the prognosis of these patients maybe to do surgery of complete tumor+lymph node resection as soon as possible.

关键词： mucinous carcinoma thyroid cancer immunohistochemistry surgery

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Invasive ductal carcinoma of the pancreas showing exophytic growth

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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 97-102页

作者： Yuichi Sanada Kazuhiro Yoshida Masaoki Itoh Riki Okita Morihito Okada Department of Surgical Oncology Research Institution for Radiation Biology and MedicineHiroshima University

BACKGROUND:Invasive pancreatic carcinoma generally appears as poorly defined mass reflecting the infiltrative *** aimed to identify the histological and immunohistochemical features in a rare case of pancreatic carcinoma showing exophytic growth. METHODS:A 67-year-old woman presented with a mass of 5.0 cm in diameter in the pancreatic *** computed tomography revealed a well-demarcated, primarily solid mass with a central low-density area. Magnetic resonance cholangiopancreatography revealed neither encasement nor dilation of the main pancreatic *** incorrect preoperative diagnosis was made of solid pseudopapillary tumor of the *** serum carcinoembryonic antigen(CEA)levels and abnormal FDG positron emmission tomography accumulation suggested that the tumor had malignant potential requiring a pancreatoduodenectomy. RESULTS:The head of the pancreas contained a well- circumscribed encapsulated mass of 5.0 cm in diameter, comprising 50%adenocarcinoma,with mucinous carci- noma in the center and anaplastic carcinoma at the *** anaplastic carcinoma comprised pleo- morphic cells(PCs)and pleomorphic giant cells(PGCs). The PGCs phagocytozed mononuclear PCs and lymphocytes adjacent to the capsule without infiltrating the capsule *** revealed that the anaplastic carcinoma cells including PGCs were positive for the tumor antigen Mucin 1 and CEA but negative for vimentin. CONCLUSION:Our observations suggest anaplastic carcinoma components in the present tumor have a ductal origin and that the exophytic tumor growth is associated with the phagocytotic activity of PGCs.

关键词： pancreatic carcinoma anaplastic carcinoma mucinous carcinoma Mucin 1 carcinoembryonic antigen

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Rapid progression of colonic mucinous adenocarcinoma with immunosuppressive condition:A case report and review of literature

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World Journal of Clinical Cases 2021年第30期9卷 9182-9191页

作者： Youhei Koseki Kenya Kamimura Yuto Tanaka Marina Ohkoshi-Yamada Qiliang Zhou Yoshifumi Matsumoto Takeshi Mizusawa Hiroki Sato Akira Sakamaki Hajime Umezu Junji Yokoyama Shuji Terai Division of Gastroenterology and Hepatology Niigata UniversityNiigata 9518510Japan Department of General Medicine Niigata UniversityNiigata 9518510Japan Department of Medical Oncology Niigata UniversityNiigata 9518510Japan Division of Pathology Niigata UniversityNiigata 9518510Japan

BACKGROUND Colorectal mucinous adenocarcinoma is a rare subtype of colorectal cancer and is characterized by an abundance of mucin in the *** addition,the colorectal mucinous adenocarcinoma often demonstrates poor differentiation in the histology of tumor cells and poor prognosis compared with those with ***,we present the case of a young woman with colonic mucinous adenocarcinoma showing significantly rapid progression within four months of immunosuppressant therapy for Henoch-Schonlein *** SUMMARY Here we report a rare case of ascending colon mucinous adenocarcinoma with lymph node and liver metastases which developed and progressed rapidly within four months during the treatment of Henoch-Schonlein purpura using *** systemic screening examinations showed no tumors before the immunosuppressant ***,the patient was successfully treated with *** While no direct evidence that the immunosuppressants accelerated the tumor development,the case presen-ta tion and review of the literature demonstrated that surveillance for malig-nancies before and during treatment with immunosuppressive agents is essential.

关键词： Colorectal cancer mucinous carcinoma Immunosuppressant Corticosteroid Case report

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mucinous colorectal adenocarcinoma:clinical pathology and treatment options

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Cancer Communications 2019年第1期39卷 122-134页

作者： Cong Luo Shuyi Cen Guojun Ding Wei Wu Department of Abdominal Oncology Zhejiang Cancer HospitalHangzhou 310022ZhejiangP.R.China School of Medicine Zhejiang UniversityHangzhou 310058ZhejiangP.R.China Department of Radiotherapy Zhejiang Cancer HospitalHangzhou 310022ZhejiangP.R.China Department of Pathology Zhejiang Cancer HospitalHangzhou 310022ZhejiangP.R.China.

mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer(CRC)characterized by the pres-ence of abundant extracellular mucin which accounts for at least 50%of the tumor *** colorectal adenocarcinoma is found in 10%-20%of CRC patients and occurs more commonly in female and younger ***,mucinous colorectal adenocarcinoma is more frequently located in the proximal colon and diagnosed at an advanced *** on its molecular context,mucinous colorectal adenocarcinoma is associated with the over-expression of mucin 2(MUC2)and mucin 5AC(MUC5AC)*** the same time,it shows higher mutation rates in the fundamental genes of the RAS/MAPK and PI3K/Akt/mTOR *** colorectal adenocarcinoma also shows higher rates of microsatellite instability(MSI)than non-mucinous colorectal adenocarcinoma which might correlate it with Lynch syndrome and the CpG island methylator *** prognosis of mucinous colorectal adenocarcinoma as to non-mucinous colorectal adenocarcinoma is ***,the impaired responses of mucinous colorectal adenocarcinoma to palliative or adjuvant chemotherapy warrant more studies to be performed for a specialized treatment for these *** this review,we discuss the molecular background and histopathol-ogy of mucinous colorectal adenocarcinoma,and provide an update on its prognosis and therapeutics from recent literatures.

关键词： Adenocarcinoma mucinous carcinoma Colorectal cancer MUC2 MUC5AC Microsatellite instability Lynch syndrome Targeted molecular therapy Hyperthermic intraperitoneal chemotherapy Immunotherapy

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Prostate mucinous Adenocarcinoma with Signet Ring Cells:a Case Report and Literature Review

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Chinese Journal of Clinical Oncology 2006年第5期3卷 379-380页

作者： Yi Wang Guang Sun Jiangang Pan Jiwu Chang Shumin Zhang Tao Li Binghuang Ren Department of Urology the Second Hospital of Tianjin Medical University 300211 China. Tianjin Institute of Urology Tianjin Medical University Tianjin 300211 China.

Prostate mucinous adenocarcinoma with signet ring cells (MC-SRC) is a rare morphologic variant of prostate cancer, with only 12 cases reported to date. Diagnosis of this carcinoma requires that at least 25% of the tumor tissue should consist of an extracellular mucin pool. In this report, we present a case of prostate prostate mucinous adenocarcinoma with signet ring cells.

关键词： prostatic cancer mucinous carcinoma signet ring cell.

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