Rapid progression of colonic mucinous adenocarcinoma with immunosuppressive condition:A case report and review of literature

作     者：Youhei Koseki Kenya Kamimura Yuto Tanaka Marina Ohkoshi-Yamada Qiliang Zhou Yoshifumi Matsumoto Takeshi Mizusawa Hiroki Sato Akira Sakamaki Hajime Umezu Junji Yokoyama Shuji Terai 

作者机构：Division of Gastroenterology and HepatologyNiigata UniversityNiigata 9518510Japan Department of General MedicineNiigata UniversityNiigata 9518510Japan Department of Medical OncologyNiigata UniversityNiigata 9518510Japan Division of PathologyNiigata UniversityNiigata 9518510Japan 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2021年第9卷第30期

页      面：9182-9191页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：  (20K08379) 

主　　题：Colorectal cancer Mucinous carcinoma Immunosuppressant Corticosteroid Case report 

摘      要：BACKGROUND Colorectal mucinous adenocarcinoma is a rare subtype of colorectal cancer and is characterized by an abundance of mucin in the *** addition,the colorectal mucinous adenocarcinoma often demonstrates poor differentiation in the histology of tumor cells and poor prognosis compared with those with ***,we present the case of a young woman with colonic mucinous adenocarcinoma showing significantly rapid progression within four months of immunosuppressant therapy for Henoch-Schonlein *** SUMMARY Here we report a rare case of ascending colon mucinous adenocarcinoma with lymph node and liver metastases which developed and progressed rapidly within four months during the treatment of Henoch-Schonlein purpura using *** systemic screening examinations showed no tumors before the immunosuppressant ***,the patient was successfully treated with *** While no direct evidence that the immunosuppressants accelerated the tumor development,the case presen-ta tion and review of the literature demonstrated that surveillance for malig-nancies before and during treatment with immunosuppressive agents is essential.