检索结果-南通市图书馆

Development of a monolithic polymer pipette for solid-phase extraction of liquiritigenin in rat plasma

Chinese Chemical Letters 2012年第6期23卷 723-726页

作者： Hong Wu Zhang Kang Li Zhi Xian Liang Feng YangWang Qi Wen Lu School of Pharmacy Guangdong Pharmaceutical College Guangzhou 510006 China

A monolithic polymer column with mixed-mode interaction was prepared by in situ polymerization in a 1000μL pipette. Two kinds of monomers, butyl methacrylate （BMA） and 2-（dimethylamino）ethyl methacrylate （DMAM） were applied to constructing the mixed-mode interaction of monolithic polymer column. Its solid-phase extraction properties for liquiritigenin （LQG） were evaluated by high performance liquid chromatography （HPLC） with a gradient elution procedure. After the extraction procedure was optimized, the maximum binding capacity and extraction recovery following the optimal extraction procedure were investigated. Calibration curve was expressed as A = 65.9C ＋ 4.53 （r2 = 0.998） with a linear range of 0.151-1.80μg/mL. The experimental results indicate that the monolithic polymer pipette presents good extraction efficiency for LQG. It can be envisaged that the developed monolithic polymer pipette possesses the potential for its application to the enrichment of other flavonoids compounds being similar to the structure of LQG.

关键词： monolithic polymer pipette Solid phase extraction High performance liquid chromatography Liquiritigenin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development of a monolithic polymer pipette for solid-phase extraction of liquiritigenin in rat plasma

Development of a monolithic polymer pipette for solid-phase ...

引用

全国生物医药色谱及相关技术学术交流会（2012）

作者：张红武 School of Pharmacy Guangdong Pharmaceutical University

A monolithic polymer column with mixed-mode function was prepared by in situ polymerization in a 1000μL *** kinds of monomers,butyl methacrylate（BMA） and 2-（dimethylamino）ethyl methacrylate（DMAM）,were applied to constructing the mixed-mode function for the synthesized polymer *** solid-phase extraction properties for liquiritigenin（LQG） were evaluated by high performance liquid chromatography（HPLC） with a gradient elution *** extraction procedure was optimized in *** then,the maximum binding capacity and extraction recovery following the optimal extraction procedure were also *** curve was expressed as A=65.9C+4.53（r 2 =0.998） with a linear range of 0.151～1.80μg/*** limit of quantification（LOQ） was estimated as 0.015μg/ml and the limit of detection（LOD） as 0.0045μg/*** experimental results indicate that the monolithic polymer pipette presents good extraction efficiency for *** monolithic polymer envisages the potential for application to the enrichment of other flavonoids compounds being similar to the structure of LQG.

关键词： monolithic polymer pipette Solid phase extraction High performance liquid chromatography Liquiritigenin

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：