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malignant fibrous histiocytoma of the bone in a traumatic amputation stump: A case report and review of the literature

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World Journal of Clinical Cases 2021年第26期9卷 7930-7936页

作者： Ke-Yang Zhao Xu Yan Peng-Fei Yao Jiong Mei Department of Orthopedic Surgery Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China Department of Orthopedics Huainan First People's HospitalHuainan 200233Anhui ProvinceChina

BACKGROUND malignant fibrous histiocytoma(MFH)is one of the most common soft tissue sarcomas among *** is characterized by large size,high grade,and biological *** are many reports of MFH after local stimulation,such as bone fracture,implants,and chronic *** this paper,we report a patient who developed MFH 6 years after amputation,suggesting that wound healing and mechanical force play a role in the local stimulation of this *** SUMMARY A 66-year-old man complained of persistent pain in his residual *** had undergone amputation surgery due to a traffic accident 6 years *** examination showed tenderness but no abnormalities in *** radiographs and magnetic resonance imaging supported the diagnosis of a tumor,and a biopsy confirmed that the lesion was *** patient received neoadjuvant chemotherapy and left hip *** the 6-mo followup,there were no symptoms of *** Postsurgery MFH has been reported before,and many studies have attributed it to the biological effects of *** case report shows that this disease can develop without an implant and thus highlights the importance of local *** wound-healing process and mechanical force can both promote this tumor,but whether they directly cause MFH needs further investigation.

关键词： malignant fibrous histiocytoma Postamputation pain Traumatic amputation Case report

Primary intestinal malignant fibrous histiocytoma:two case reports

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World Journal of Gastroenterology 2007年第8期13卷 1299-1302页

作者： De-Liang Fu Feng Yang Ashish Maskay Jiang Long Chen Jin Xian-Jun Yu Jin Xu Zhong-Wen Zhou Quan-Xing Ni Department of General Surgery Huashan Hospital Shanghai Medical College Fudan University Shanghai 200040 China Department of Pathology Huashan Hospital Shanghai Medical College Fudan University Shanghai 200040 China

malignant fibrous histiocytoma (MFH) occurs most commonly in the extremities and trunk, but rarely in the intestine. Here we report two cases of primary intestinal MFH. The first case was a 70-year old man admitted for recurrent right lower quadrant abdominal pain. At laparotomy, a tumor was found originating from the cecum, with a suspicious metastatic nodule on the surface of the right lobe of the liver. A right hemicolectomy was performed followed by an ileotransverse end-to-end anastomotic reconstruction. The second case was a 43-year old man with intussusceptions of the small intestine. An emergent laparotomy revealed 4 pedunculated masses in the small bowel and a partial resection of the small intestine was performed. Though the symptoms were not typical, based on histological and immunohistochemical studies, the patients were diagnosed as MFH of the intestine. They were not treated with chemotherapy or radiotherapy and both died within 3 mo. MFH of the intestine is an extremely rare neoplasm with an aggressive biological behavior. The pathogenesis of this disease has not been clarified to date. Complete surgical excision is preferred, adjuvant chemotherapy or radiotherapy may be advisable.

关键词： malignant fibrous histiocytoma Intestinal neoplasms Abdominal pain

A case of primary malignant fibrous histiocytoma of the pancreas: CT and MRI findings

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World Journal of Gastroenterology 2008年第18期14卷 2942-2945页

作者： Ri-Sheng Yu Jia-Wei Wang Ying Chen Wen-Hong Ding Xiu-Fang Xu Li-Rong Chen Department of Radiology Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 Zhejiang Province China Department of Pathology Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 Zhejiang Province China

Primary malignant fibrous histiocytoma (MFH) of the pancreas is rare and a distinct clinical entity. We report a case of recurrence of pancreatic MFH with computed tomography (CT) and magnetic resonance imaging (MRI) findings. A 67-year-old man presented with a history of decreased body weight over the past 6 mo. Abdominal CT revealed a large, multilocular cystic mass in the head of the pancreas with obvious atrophy in the body and tail of the pancreas. After 6 mo postoperatively, MRI demonstrated a recurrent large mass in the primary area of the head of the pancreas. The lesion was heterogeneous, hypointense to the liver on T1-weighted imaging, and heterogeneously hyperintense to the liver with a hypointense area in the central part of the tumor on fat-saturated T2-weighted imaging. Contrast- enhanced T1-weighted imaging demonstrated a large multilocular cystic mass with a cystic wall, fibrous septa and enhancement of solid components. To the best of our knowledge, this is the first report on recurrence of primary MFH of the pancreas, and the first with MRI findings.

关键词： Pancreatic neoplasms malignant fibrous histiocytoma Computed tomography Magnetic resonance imaging Tumor recurrence

Transanal excision of a malignant fibrous histiocytoma of anal canal:A case report and literature review

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World Journal of Gastroenterology 2008年第9期14卷 1459-1462页

作者： Beom Gyu Kim In Taik Chang Jun Seok Park Yoo Shin Choi Gi Hyeon Kim Eon Sub Park Chang Hwan Choi Department of Surgery College of MedicineChung-Ang University Seoul 156-755Korea Department of Radiology College of MedicineChung-Ang University Seoul 156-755Korea Department of Pathology College of MedicineChung-Ang University Seoul 156-755 Korea Department of Internal Medicine College of Medicine Chung-Ang UniversitySeoul 156-755Korea

malignant fibrous histiocytoma, which is composed of spindle-shaped cells arranged in a pleomorphic and storiform pattern, is rarely found in the colorectum. Although complete surgical excision remains the main stem of therapy, an optimal treatment strategy according to the stage has not been elucidated. We report a case of a 63-year-old woman with an ulcerative lesion in the anorectal junction and a final diagnosis of malignant fibrous histiocytoma. We introduced an access for transanal local excision and adjuvant radiotherapy because the patient refused abdominoperineal resection. No local recurrences or distant metastases were observed 15 mo after the operation. To our knowledge, this is the first case reported in the English literature of a malignant fibrous histiocytoma treated with the transana local excision and adjuvant radiotherapy. This report showed that this approach is selectively reserved for early-stage malignant fibrous histiocytoma and for those patients who refuse radical surgery because of the risk in a permanent colostomy.

关键词： malignant fibrous histiocytoma Anorectal junction Transanal local excision

A comparison of malignant fibrous histiocytoma of head, neck and extremities

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Chinese Medical Journal 2000年第6期113卷 52-55页

作者：吴雪溪祁永发唐平章 Department of Head and Neck Surgery Cancer Hospital Peking Union Medical College Beijing 100021 China Department of Head and Neck Surgery Cancer Hospital Beijing 100021 China

Objective To compare the epidemiology, local and regional invasion and prognosis of head and neck malignant fibrous histiocytoma (MFH) and extremity MFH Methods Between January 1, 1972 and December 31, 1993, 173 patients with MFH (71 head and neck, 102 extremities and trunk) were referred to the Cancer Hospital for surgical treatment They were 101 men and 72 women, with age ranging from 13 to 83 years (median: 45 years) The extent of surgery was classified into radical, wide and local resection Results For head and neck, local recurrence of MFH after wide resection was 80 4% (37/46), compared with 36.4% (8/22) after radical surgery ( P =0 000) The five year survival was 50 79% in all the head and neck patients (74 75% in patients free of local recurrence, 37 74% in patients with local recurrence; P =0 0181), compared with 70 71% in extremity patients ( P =0 0005) Repeated surgery after recurrence of MFH could cure 40 9% of the head and neck patients and 80 7% of the extremity patients Conclusion Inadequate resection of head and neck MFH in initial surgery is associated with a high incidence of local recurrence, which is always correlated with worse prognosis Repeated surgery for recurrent head and neck MFH is not as effective as for recurrent extremity MFH Therefore, we suggest that the initial surgery for head and neck MFH should be as radical as allowed to avoid a possible local recurrence

关键词： malignant fibrous histiocytoma head and neck surgical treatment

A case of malignant fibrous histiocytoma of the head after trauma and radiation therapy

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The Chinese-German Journal of Clinical Oncology 2009年第5期8卷 300-302页

作者： S. Mourgela A. Sakellaropoulos K. Kirgiannis A. Spanos Neurosurgical Department "Agios Savvas" Anticancer InstituteAthens Greece Pulmonary and Critical Care Medicine Athens Greece

malignant fibrous histiocytoma(MFH) firstly described as"malignant fibrous xanthoma"by O' Brien and Stout in 1964, is the most common soft tissue sarcoma of late adult *** histogenesis and numerous subtypes make MFH a rather controversial *** only rare arises from structures of the head and *** it does, it most often originates in facial structures, particularly the *** report details a case of a patient with malignant fibrous histiocytoma presenting clinically as a right-sided large indurated frontoparietal mass, three months after head trauma and eight years after radiation therapy for brain lymphoma located in the right frontal and parietal *** excision was a surgical challenge because of the extensiveness of the lesion.

关键词： malignant fibrous histiocytoma brain lymphoma head trauma

Early Recurrence of a Cardiac malignant fibrous histiocytoma

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World Journal of Cardiovascular Surgery 2013年第5期3卷 139-142页

作者： Laura Reija Lopez Angela Granda Bauza Jose Manuel Martínez Cereijo Jose Rubio Alvarez Belén Adrio Nazar Juan Sierra Quiroga Complexo Hospitalario Universitario de Santiago de Compostela A CorunaSpain

malignant fibrous histiocytoma (MFH) is a rare tumor of the heart and the patients with these tumors usually have a poor prognosis. We report a case of MFH with an origin from the left superior pulmonary vein, involving the left atrium and protruding through the mitral valve, which needed urgent surgery. Complete resection was performed but local recurrence was detected one month later.

关键词： malignant fibrous histiocytoma Early Recurrence

Primary malignant fibrous histiocytoma of the esophagus: Report of three cases and review of the literatures

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The Chinese-German Journal of Clinical Oncology 2007年第5期6卷 503-506页

作者： Mingyao Wu Liping Kuang Chaoxia Li Department of Pathology the Key Immunopathology Laboratory of Guangdong Province Shantou University Medical College Shantou 515041 China Guangzhou Red Cross Hospital Guangzhou 510220 China

We reported three cases of polypoid tumor of the esophagus, among them one case of sarcomatous tumor partly covered with superficial squamous cell carcinoma. The sarcoma was consisted of anaplastic spindle and pleomorphic tumor cells, which was similar to malignant fibrous histiocytoma (MFH) of the soft tissue. Diagnosis of the surgery resected speci-men was confirmed by histological, immunohistochemical and electron microscopic methods. Both diagnostic and differential diagnostic problems of primary MFH of the esophagus and world medical literatures were discussed.

关键词： esophageal neoplasm malignant fibrous histiocytoma

Large,unresectable malignant fibrous histiocytoma:PET/CT-guided treatment with a multidisciplinary,minimally invasive approach

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Large,unresectable malignant fibrous histiocytoma:PET/CT-gui...