Malignant fibrous histiocytoma of the bone in a traumatic amputation stump: A case report and review of the literature
作者机构：Department of Orthopedic SurgeryShanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China Department of OrthopedicsHuainan First People's HospitalHuainan 200233Anhui ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第26期
页 面：7930-7936页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Malignant fibrous histiocytoma Postamputation pain Traumatic amputation Case report
摘 要：BACKGROUND Malignant fibrous histiocytoma(MFH)is one of the most common soft tissue sarcomas among *** is characterized by large size,high grade,and biological *** are many reports of MFH after local stimulation,such as bone fracture,implants,and chronic *** this paper,we report a patient who developed MFH 6 years after amputation,suggesting that wound healing and mechanical force play a role in the local stimulation of this *** SUMMARY A 66-year-old man complained of persistent pain in his residual *** had undergone amputation surgery due to a traffic accident 6 years *** examination showed tenderness but no abnormalities in *** radiographs and magnetic resonance imaging supported the diagnosis of a tumor,and a biopsy confirmed that the lesion was *** patient received neoadjuvant chemotherapy and left hip *** the 6-mo followup,there were no symptoms of *** Postsurgery MFH has been reported before,and many studies have attributed it to the biological effects of *** case report shows that this disease can develop without an implant and thus highlights the importance of local *** wound-healing process and mechanical force can both promote this tumor,but whether they directly cause MFH needs further investigation.
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