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A novel quality evaluation method for magnolia bark using electronic nose and colorimeter data with multiple statistical algorithms

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Journal of Traditional Chinese Medical Sciences 2020年第2期7卷 221-227页

作者： Jiahui Li Yuanyang Shao Yuebao Yao Yuetong Yu Guangzhao Cao Huiqin Zou Yonghong Yan School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing102488China

Background:magnolia bark(magnolia Officinalis REHD.&*** magnolia officinalis REHD.&*** REHD.&WILS,Hou Po in Chinese),is widely applied in clinical prescriptions and Chinese patent *** place is a crucial factor affecting the quality of Hou Po,and chemical composition is an important index for evaluating its quality,which is closely related to its clinical *** study aims to develop a novel method for rapidly,accurately and comprehensively identifying the origin places of Hou Po and predicting the contents of its important chemical ***:High performance liquid chromatography was used to analyze the contents of magnolol and honokiol and ultra-performance liquid chromatography the contents of magnocurarine and *** cold soak method was used to determine the contents of water-soluble *** E-nose and colorimeter were used to determine the odor and color characteristics,respectively,of the collected Hou Po ***:Using several statistical algorithms,different discriminant models based on the E-nose and colorimeter data were established to distinguish the origin place of Hou-Po and predict the chemical components of honokiol,magnolol,magnocurarine,magnoflorine and water-soluble *** results showed that the Random Forest classifier combined with the ten-fold cross-validation method provided the highest classification accuracy for origin place,accounting for 99.53%among these *** correlation coefficients between predicted and experimental values of the five chemical components were all higher than ***:This study has indicated that the electronic nose and colorimeter are promising methods for evaluating the quality of Chinese herbal medicines both qualitatively and quantitatively.

关键词： magnolia bark Electronic nose Colorimeter Origin place Quality evaluation

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Biological activity and toxicity of the Chinese herb magnolia officinalis Rehder & E. Wilson(Houpo) and its constituents

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第3期18卷 194-214页

作者： Melanie POIVRE Pierre DUEZ (Unit of Therapeutic Chemistry and Pharmacognosy Faculty of Medicine and Pharmacy Research Institute for Health Sciences and Technology University of Mons-UMONS Mons Belgium

Traditional Chinese herbal drugs have been used for thousands of years in Chinese pharmacopoeia. The bark of magnolia officinalis Rehder ＆ E. Wilson, known under the pinyin name ＂Houpo＂, has been traditionally used in Chinese and Japanese medicines for the treatment of anxiety, asthma, depression, gastrointestinal disorders, headache, and more. Moreover, magnolia bark extract is a major constituent of currently marketed dietary supplements and cosmetic products. Much pharmacological activity has been reported for this herb and its major compounds notably antioxidant, anti-inflammatory, antibiotic and antispasmodic effects. However, the mechanisms underlying this have not been elucidated and only a very few clinical trials have been published. In vitro and in vivo toxicity studies have also been published and indicate some intriguing features. The present review aims to summarize the literature on M. officinalis bark composition, utilisation, pharmacology, and safety.

关键词： magnolia bark Houpo Chinese herb Traditional Chinese medicine

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