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magnetic compression anastomosis for reconstruction of digestive tract after total gastrectomy in beagle model

World Journal of Gastrointestinal Surgery 2023年第7期15卷 1294-1303页

作者： Miao-Miao Zhang Chen-Guang Li Shu-Qin Xu Jian-Qi Mao Yu-Han Zhang Ai-Hua Shi Yan Li Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Critical Care Medicine China-Japan Union Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Zonglian College Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Qide College Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

BACKGROUND magnetic compression anastomosis(MCA)is a simple procedure contributing to a reliable ***,digestive-tract reconstruction after total gastrectomy using MCA has not yet been *** To investigate the feasibility of MCA for simultaneous esophagojejunostomy and jejunojejunostomy after total gastrectomy using beagle *** Sixteen beagles were randomly divided into an MCA group(study group,n=8)and a manual-suture anastomosis group(control group,n=8).Two different magnetic anastomosis devices were used in the study group for esophagojejunal and jejunojejunal *** devices included a pair of circular daughter and parent magnets *** time of esophagojejunostomy and jejunojejunostomy,postoperative complications,and survival rate of the two groups were *** dogs were sacrificed one month after the operation and their anastomotic specimens were *** was observed by the naked eye and a light *** Digestive-tract reconstruction after total gastrectomy was successfully completed in both groups(survival rate=100%).In the study group,esophagojejunal and jejunojejunal anastomoses took 6.13±0.58 and 4.06±0.42 min,respectively,significantly lower than those in the control group(15.63±1.53 min,Pmagnetic anastomosis device was 10.75±1.28 d,while that of the esophagojejunal magnetic anastomosis device was 12.25±1.49 *** silk was found in the control *** study group showed a greater smoothness of the anastomosis than that of the control *** layers of anastomosis healed well in both *** MCA is a safe and feasible procedure for digestive-tract reconstruction after total gastrectomy in this animal model.

关键词： magnetic surgery magnetic compression anastomosis Gastric cancer Total gastrectomy Roux-en-Y esophagojejunal anastomosis Beagles

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magnetic compression anastomosis to restore biliary tract continuity after obstruction following major abdominal trauma:A case report

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1933-1938页

作者： Miao-Miao Zhang Jie Tao Huan-Chen Sha Yun Li Xiao-Gang Song Oliver J Muensterer Fang-Fang Dong Li Zhang Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Shaanxi Provincial Key Laboratory of magnetic Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Pediatric Surgery Dr.von Hauner Children’s HospitalLudwig-Maximilians-University Medical CenterMunich 80337Germany

BACKGROUND The combination of magnetic compression anastomosis(MCA)and endoscopy has been used to treat biliary stricture after liver ***,its use for the treatment of complex biliary obstruction after major abdominal trauma has not been *** case report describes the successful use of MCA for the treatment of biliary obstruction resulting from major abdominal trauma.A 23-year-old man underwent major abdominal surgery(repair of liver rupture,right half colon resection,and ileostomy)following a car accident one year *** abdominal drainage tube,positioned at the Winslow foramen,was draining approximately 600-800 mL of bile per *** the two endoscopic retrograde cholangiopancreatography procedures,the guide wire was unable to enter the common bile duct,which prevented placement of a biliary *** combined with endoscopy was used to successfully achieve magnetic anastomosis of the peritoneal sinus tract and duodenum,and then a choledochoduodenal stent was ***,the external biliary drainage tube was *** patient achieved internal biliary drainage leading to the removal of the external biliary drainage tube,which improved the quality of *** magnetic compression technique can be used for the treatment of complex biliary obstruction with minimal operative trauma.

关键词： magnetic compression anastomosis Magnetosurgery Endoscopy magnetic Surgery Clinic Biliary obstruction Case report

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Fedora-type magnetic compression anastomosis device for intestinal anastomosis

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World Journal of Gastroenterology 2020年第42期26卷 6614-6625页

作者： Huan Chen Tao Ma Yue Wang Hao-Yang Zhu Zhe Feng Rong-Qian Wu Yi Lv Ding-Hui Dong National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Although previous studies have confirmed the feasibility of magnetic compression anastomosis(MCA),there is still a risk of long-term anastomotic *** traditional MCA devices,a large device is associated with great pressure,and eventually increased *** To develop a novel MCA device to simultaneously meet the requirements of pressure and *** Traditional nummular MCA devices of all possible sizes were used to conduct ileac anastomosis in *** mean(±SD)circumference of the ileum was 13.34±0.12 *** on short-and long-term follow-up results,we determined the appropriate pressure range and minimum ***,we introduced a novel“fedora-type”MCA device,which entailed the use of a nummular magnet with a larger sheet *** With traditional MCA devices,the anastomoses experienced stenosis and even closure during the long-term follow-up when the anastomat was smaller thanΦ5 ***,the risk of leakage increased when it was larger thanΦ4 *** comparison of the different designs,it was found that the“fedora-type”MCA device should be composed of aΦ4-mm nummular magnet with aΦ6-mm sheet *** The diameter of the MCA device should be greater than 120%of the enteric *** novel“fedora-type”MCA device controls the pressure and optimizes the size.

关键词： magnetic compression anastomosis Anastomotic stenosis Size of anastomat compression pressure Fedora-type magnetic compression anastomosis device

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magnetic compression anastomosis for sigmoid stenosis treatment:A case report

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World Journal of Gastrointestinal Endoscopy 2023年第12期15卷 745-750页

作者： Miao-Miao Zhang Yi Gao Xiao-Yang Ren Huan-Chen Sha Yi Lyu Fang-Fang Dong Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Gastrointestinal Surgery Affiliated Hospital of Guilin Medical UniversityGuilin 541001Guangxi Zhuang Autonomous RegionChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

BACKGROUND Endoscopic balloon dilation is a minimally invasive treatment for colorectal *** compression anastomosis can be applied against gastrointestinal *** combined with endoscopy,it offers a unique approach to the recanalization of colorectal *** SUMMARY We have reported here the case of a 53-year-old female patient who underwent a descending colostomy due to sigmoid *** fistula restoration was not possible in her due to sigmoid ***,endoscopicassisted magnetic compression anastomosis for sigmoid stenosis was performed,and the sigmoid stenosis was recanalized 15 d after the ***,a reduction colostomy was successfully performed after 10 *** This case report proposes a novel minimally invasive treatment approach for colorectal stenosis.

关键词： Colorectal stenosis Endoscopy magnetic compression anastomosis Magnamosis Magnetosurgery Case report

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Primary repair of esophageal atresia gross type C via thoracoscopic magnetic compression anastomosis:A case report

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2919-2925页

作者： Hong-Ke Zhang Xiao-Quan Li Hong-Xia Song Shi-Qi Liu Fang-Hui Wang Jian Wen Mi Xiao A-Ping Yang Xu-Feng Duan Zhen-Zhen Gao Kai-Lun Hu Wei Zhang Yi Lv Xi-Hui Zhou Zhen-Jie Cao Department of Pediatric Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shannxi ProvinceChina Department of Neonatology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shannxi ProvinceChina Department of Neonatal Surgery Xi’an Children’s HospitalXi’an 710003Shannxi ProvinceChina Department of Anesthesiology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shannxi ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shannxi ProvinceChina

BACKGROUND Esophageal atresia(EA)is a life-threatening congenital malformation in newborns,and the traditional repair approaches pose technical challenges and are extremely ***,surgeons have been actively investigating new minimally invasive techniques to address this *** compression anastomosis has been reported in several studies for its potential in repairing *** this paper,the primary repair of EA with magnetic compression anastomosis under thoracoscopy was *** SUMMARY A full-term male weighing 3500 g was diagnosed with EA gross type *** magnetic devices used in this procedure consisted of two magnetic rings and several *** fistula ligation and two purse strings were *** magnetic compression anastomosis was then completed *** the primary repair,no additional operation was conducted.A patent anastomosis was observed on the 15th day postoperatively,and the magnets were removed on the 23rd *** leakage existed when the transoral feeding *** Thoracoscopic magnetic compression anastomosis may be a promising minimally invasive approach for repairing EA.

关键词： Congenital esophageal atresia Minimal invasive surgery Thoracoscopic repair magnetic compression anastomosis Primary repair Case report

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Sutureless Intestinal anastomosis with a Novel Device of magnetic compression anastomosis

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Chinese Medical Sciences Journal 2011年第3期26卷 182-189页

作者： Chao Fan Jia Ma Hong-ke Zhang Rui Gao Jian-hui Li Liang Yu Zheng Wu Yi Lv Department of Hepatobiliary Surgery the First Affiliated HospitalMedical School of Xi＇an Jiaotong UniversityXi＇an 710061China

Objective To explore the feasibility and efficiency of a novel magnetic compression anastomats(MCAs) in intestinal *** A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn(n=18) or a novel MCAs(n=18).We compared the anastomosis time,postoperative complications,bursting strength of anastomoses,gross appearance,and pathology between two groups at each time-point of *** The mean anastomosis time with MCAs was significantly less than that with hand-sewn(8.50±1.95 vs.31.1±4.32 minutes,Panastomosis by MCAs experienced anastomotic *** average bursting pressure of anastomoses obtained from mongrel canines undergoing intestinal anastomosis by MCAs was significantly higher than that by traditional hand-sewn at 1 week's follow-up time(Pmagnetic *** The magnetic compression anastomat is a safe and effective device of sutureless intestinal anastomosis in canine models.

关键词： magnetic compression anastomosis bursting strength foreign body reaction

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Fast magnetic reconstruction of the portal vein with allogeneic blood vessels in canines

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Hepatobiliary & Pancreatic Diseases International 2015年第3期14卷 293-299页

作者： Shan-Pei Wang Xiao-Peng Yan Fei Xue Ding-Hui Dong Xu-Feng Zhang Feng Ma Hao-Hua Wang Yi Lv Department of Hepatobiliary Surgery First Affiliated Hospital Medical School of Xi'an Jiaotong University Regenerative Medicine and Surgery Engineering Research Center of Shaanxi Province

BACKGROUND： The resection and reconstruction of large vessels, including the portal vein, are frequently needed in tumor resection. Warm ischemia before reconstruction might have deleterious effects on the function of some vital organs and therefore, how to reconstruct the vessels quickly after resection is extremely important. The present study was to introduce a new type of magnetic compression anastomosis （MCA） device to establish a quick non-suture anastomosis of the portal vein after resection in canines.

关键词： magnetic compression anastomosis portal vein reconstruction non-suture anastomosis

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Influence of different magnetic forces on the effect of colonic anastomosis in rats

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 860-870页

作者： Bo-Yan Tian Miao-Miao Zhang Jia Ma Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Surgical Oncology Shaanxi Provincial People's HospitalXi'an 710068Shaanxi ProvinceChina

BACKGROUND Despite much work having been conducted on magnetic compression anastomo-sis(MCA)in the digestive tract,there are no reports on the influence of magnetic force on the *** To investigate the effect of different magnetic force magnets on the MCA of the digestive *** Two groups of magnets of the same sizes but different magnetic forces were designed and produced.A total of 24 Sprague-Dawley rats were randomly assigned into two groups(powerful magnet group and common magnet group),with 12 rats in each *** types of magnets were used to complete the colonic side-to-side anastomosis of the *** operation time and magnet discharge time were *** anastomotic specimens were obtained 4 wk after the operation and then the burst pressure and diameter of the anastomosis were measured,and the anastomosis was observed via the naked eye and subjected to histological *** The magnetic forces of the powerful and common magnet groups at zero distance were 8.26 N and 4.10 N,*** colonic side-to-side anastomosis was completed in all 24 rats,and the operation success rate and postoperative survival rate were 100%.No significant difference was noted in the operation time between the two *** magnet discharge time of the powerful magnet group was slightly longer than that of the common magnet group,but the difference was not statistically significant(P=0.513).Furthermore,there was no statistical difference in the burst pressure(P=0.266)or diameter of magnetic anastomosis(P=0.095)between the two *** gross specimens of the two groups showed good anastomotic healing,and histological observation indicated good mucosal continuity without differences on *** In the rat colonic side-to-side MCA model,both the powerful magnet with 8.26 N and the common magnet with 4.10 N showed no significant impact on the anastomosis establishment process or its effect.

关键词： Magnetosurgery magnetic compression anastomosis Colonic anastomosis magnetic force Rats

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Combined endoscopy/laparoscopy/percutaneous transhepatic biliary drainage, hybrid techniques in gastrointestinal and biliary diseases

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World Journal of Meta-Analysis 2020年第3期8卷 210-219页

作者： Yi-Long Feng Jing Li Lian-Song Ye Xian-Hui Zeng Bing Hu Department of Gastroenterology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

In recent years,a wide range of gastrointestinal endoscopy techniques have been developed,such as endoscopic submucosal dissection(ESD)and endoscopic retrograde cholangiopancreatography(ERCP).Although ESD and ERCP have an important role in gastrointestinal and biliary diseases,each technique has its *** techniques that combine endoscopic and surgical procedures have emerged that have the advantages of different procedures and negate their limitations at the same *** endoscopic cooperative surgery and modified laparoscopic endoscopic cooperative surgery combine ESD and laparoscopic techniques to resect submucosal tumors with minimum resection *** leak test by intraoperative endoscopy can effectively identify a mechanically insufficient anastomosis and decrease the complication *** rendezvous technique that combines percutaneous transhepatic biliary drainage and endoscopy can be performed as a rescue approach for the treatment of biliary obstruction,stenosis and bile duct *** patients with simultaneous presence of stones in the gallbladder and the common bile duct,the laparoendoscopic rendezvous technique can perform ERCP and laparoscopic cholecystectomy at the same time and reduces the risk of pancreatic injury caused by *** and bilioenteric anastomosis using magnetic compression anastomosis is another choice for biliary *** most common used approach to deliver the magnets is by percutaneous-peroral *** ERCP is a safe and highly effective therapy for patients who develop biliary diseases after Roux-en-Y gastric bypass surgery.

关键词： Hybrid technique Laparoscopic and endoscopic cooperative surgery Endoscopic retrograde cholangiopancreatography Laparoscopic-assisted endoscopic retrograde cholangiopancreatography Rendezvous technique magnetic compression anastomosis

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