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Full recovery from chronic headache and hypopituitarism caused by lymphocytic hypophysitis:A case report

World Journal of Clinical Cases 2022年第3期10卷 1041-1049页

作者： Mao-Guang Yang Han-Qing Cai Si-Si Wang Lin Liu Chun-Mei Wang Department of Endocrinology The Second Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Department of Radiology The First Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina

BACKGROUND lymphocytic hypophysitis(LYH)is an important condition to consider in the differential diagnosis of patients with a pituitary *** main clinical manifestations of LYH include headache,symptoms related to sellar compression,hypopituitarism,diabetes insipidus and ***,which is a frequent complaint of patients with LYH,is thought to be related to the occupying effect of the pituitary mass and is rapidly resolved with a good outcome after timely and adequate glucocorticoid treatment or *** SUMMARY Here,we report a patient with LYH whose initial symptom was headache and whose pituitary function assessment showed the presence of secondary hypoadrenalism,central hypothyroidism and hypogonadotropic *** magnetic resonance imaging showed symmetrical enlargement of the pituitary gland with suprasellar extension in a dumbbell shape with significant homogeneous enhancement after gadolinium *** size of the gland was approximately 17.7 mm×14.3 mm×13.8 *** pituitary stalk was thickened without deviation,and there was an elevation of the optimal *** lesion grew bilaterally toward the cavernous sinuses,and the parasternal dural caudal sign was *** patient presented with repeatedly worsening and prolonged headaches three times even though the hypopituitarism had fully resolved after glucocorticoid treatment during this *** This rare headache regression suggests that patients with chronic headaches should also be alerted to the possibility of LYH.

关键词： lymphocytic hypophysitis Magnetic resonance imaging Hypopituitarism Headache Glucocorticoid Case report

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