Full recovery from chronic headache and hypopituitarism caused by lymphocytic hypophysitis:A case report

作     者：Mao-Guang Yang Han-Qing Cai Si-Si Wang Lin Liu Chun-Mei Wang 

作者机构：Department of EndocrinologyThe Second Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Department of RadiologyThe First Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第3期

页      面：1041-1049页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the Nature Science Foundation of Jilin Province(No.2018010113JC) 

主　　题：Lymphocytic hypophysitis Magnetic resonance imaging Hypopituitarism Headache Glucocorticoid Case report 

摘      要：BACKGROUND Lymphocytic hypophysitis(LYH)is an important condition to consider in the differential diagnosis of patients with a pituitary *** main clinical manifestations of LYH include headache,symptoms related to sellar compression,hypopituitarism,diabetes insipidus and ***,which is a frequent complaint of patients with LYH,is thought to be related to the occupying effect of the pituitary mass and is rapidly resolved with a good outcome after timely and adequate glucocorticoid treatment or *** SUMMARY Here,we report a patient with LYH whose initial symptom was headache and whose pituitary function assessment showed the presence of secondary hypoadrenalism,central hypothyroidism and hypogonadotropic *** magnetic resonance imaging showed symmetrical enlargement of the pituitary gland with suprasellar extension in a dumbbell shape with significant homogeneous enhancement after gadolinium *** size of the gland was approximately 17.7 mm×14.3 mm×13.8 *** pituitary stalk was thickened without deviation,and there was an elevation of the optimal *** lesion grew bilaterally toward the cavernous sinuses,and the parasternal dural caudal sign was *** patient presented with repeatedly worsening and prolonged headaches three times even though the hypopituitarism had fully resolved after glucocorticoid treatment during this *** This rare headache regression suggests that patients with chronic headaches should also be alerted to the possibility of LYH.