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Ultrasonic Characteristics and Severity Assessment of lung ultrasound in COVID-19 Pneumonia:A Retrospective,Observational Study

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Engineering 2021年第3期7卷 367-375页

作者： Fengxue Zhu Xiujuan Zhao Tianbing Wang Zhenzhou Wang Fuzheng Guo Haiyan Xue Panpan Chang Hansheng Liang Wentao Ni Yaxin Wang Lei Chen Baoguo Jiang Trauma Center Citical Care Medicine DepartmentPeking University People's HospitalBeijing 100044China Trauma Center Key Laboratory of Trauna and Neurad Regeneration(Peling Univerity)Minisiry of EducationPeking Universty Peole's Hiospital lejing 100044China Anesthesioogy Department Peking Uhniversity People's HospitalBeijing 100044China Respiratory and Griticnl Care Medicine Depariment Peking Lniversity People's HospitalBeiing 10004China Raiology Deparment Peking University People's HospitalBeijing 100044China

The clinical application of lung ultrasound(LS)in the assessment of coronavirus disease 2019(COVID-19)pneumonia severity remains limited,Herein,we investigated the role of LUS imaging in CoVID-19pneumonia patients and the relationship between LUS findings and disease *** was a retro-spective,observational study at Tongji Hospital,on 48 recruited patients with COVID-19 pneu-monia,including 32 non-critically ill patients and 16critically ill *** was performed and the respiratory rate oxygenation(ROX)index,disease severity,and confusion,blood urea nitrogen,respira-tory rate,blood pressure,and age(CURB-65)score were recorded on days 0-7,8-14,and 15-21 after *** images were divided into 12 regions,and the luS score(0-36 points)was *** tomography(CT)scores(0-20 points)were also recorded on days *** between the LUS score,ROX index,and CURB-65 scores were *** detected COVID-19 pneumonia in *** signs included B lines(34/38,89.5%),consolidations(6/38,15.8%),and pleural effusions(2/38,5.3%).Most cases showed more than one lesion(32/38,84.2%)and involved both lungs(28/38,73.7%).Compared with non-critically ill patients,the LUS scores of critically ill patients were higher(12(10-18)vs 2(0-5),plunglesions in COVID-19 pneumo-nia patients in a portable,real-time,and safe ***,LUS is helpful in assessing COVID-19 pneu-monia severity in critically ill patients.

关键词： Coronavirus disease 2019 lung ultrasound Pneumonia

High-flow nasal cannula oxygen therapy and noninvasive ventilation for preventing extubation failure during weaning from mechanical ventilation assessed by lung ultrasound score: A single-center randomized study

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World Journal of Emergency Medicine 2021年第4期12卷 274-280页

作者： Shan-xiang Xu Chun-shuang Wu Shao-yun Liu Xiao Lu Emergency Department the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhou 310009China

BACKGROUND: We sought to demonstrate the superiority of a targeted therapy strategy involving high-flow nasal cannula oxygen(HFNCO_(2)) therapy and noninvasive ventilation(NIV) using lung ultrasound score(LUS) in comparison with standard care among patients in the intensive care unit(ICU) who undergo successful weaning to decrease the incidence of extubation failure at both 48 hours and seven ***: During the study period, 98 patients were enrolled in the study, including 49 in the control group and 49 in the treatment group. Patients in the control group and patients with an LUS score <14 points(at low risk of extubation failure) in the treatment group were extubated and received standard preventive care without NIV or HFNCO_(2). Patients with an LUS score ≥14 points(at high risk of extubation failure) in the treatment group were extubated with a second review of the therapeutic optimization to identify and address any persisting risk factors for postextubation respiratory distress;patients received HFNCO2 therapy combined with sessions of preventive NIV(4-8 hours per day for 4-8 sessions total) for the first 48 hours after ***: In the control group, 13 patients had the LUS scores ≥14 points, while 36 patients had scores <14 points. In the treatment group, 16 patients had the LUS scores ≥14 points, while 33 patients had scores <14 points. Among patients with the LUS score ≥14 points, the extubation failure rate within 48 hours was 30.8% in the control group and 12.5% in the treatment group, constituting a statistically significant difference(P<0.05). Conversely, among patients with an LUS score <14 points, 13.9% in the control group and 9.1% in the treatment group experienced extubation failure(P=0.61). The length of ICU stay(9.4±3.1 days vs. 7.2±2.4 days) was significantly different and the re-intubation rate(at 48 hours: 18.4% vs. 10.2%;seven days: 22.4% vs. 12.2%) significantly varied between the two groups(P<0.05). There was no significan

关键词： High-flow nasal cannula oxygen Noninvasive ventilation lung ultrasound Extubation

Innovative integration of lung ultrasound and wearable monitoring for predicting pulmonary complications in colorectal surgery:A prospective study

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2649-2661页

作者： Chen Lin Pei-Pei Wang Zi-Yan Wang Guo-Ru Lan Kai-Wen Xu Chun-Hua Yu Bin Wu Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China School of Medicine Tsinghua UniversityBeijing 100084China Department of Anesthesiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Clinical Laboratory Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

BACKGROUND Postoperative pulmonary complications(PPCs)are common in patients who undergo colorectal *** have focused on how to accurately diagnose and reduce the incidence of *** ultrasound has been proven to be useful in preoperative monitoring and postoperative care after cardiopulmonary ***,lung ultrasound has not been studied in abdominal surgeries and has not been used with wearable devices to evaluate the influence of postoperative ambulation on the incidence of *** To investigate the relationship between lung ultrasound scores,PPCs,and postoperative physical activity levels in patients who underwent colorectal *** In this prospective observational study conducted from November 1,2019 to August 1,2020,patients who underwent colorectal surgery underwent daily bedside ultrasonography from the day before surgery to postoperative day(POD)*** ultrasound scores and PPCs were recorded and analyzed to investigate their *** bracelets measured the daily movement distance for 5 days post-surgery,and the correlation between postoperative activity levels and lung ultrasound scores was *** Thirteen cases of PPCs was observed in the cohort of 101 *** mean(standard deviation)peak lung ultrasound score was 5.32(2.52).Patients with a lung ultrasound score of≥6 constituted the high-risk ***-risk lung ultrasound scores were associated with an increased incidence of PPCs after colorectal surgery(logistic regression coefficient,1.715;odds ratio,5.556).Postoperative movement distance was negatively associated with the lung ultrasound scores[Spearman’s rank correlation coefficient(r),-0.356,Plung ultrasound effectively evaluates pulmonary condition post-colorectal *** ambulation and respiratory exercises in the initial two PODs will reduce PPCs and optimize postoperative care in patients undergoing colorectal surgery.

关键词： Colorectal cancer Pulmonary complications lung ultrasound Wearable devices Respiratory exercises

Evaluation value of lung ultrasound combined with CRP and PCT on the efficacy and prognosis of HAP

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实用休克杂志（中英文） 2022年第4期6卷 247-256页

作者： Zeng Qinbing Chen Xiaojie Guan Jian Li Liming Liu Yijun Han Jiaqi Chao Yangong Beijing Huaxin Hospital(The First Affiliated Hospital of Tsinghua University) Intensive care unit Wangjing Hospital Chinese Academy of Traditional Chinese Medicine emergency Beijing Huaxin Hospital(The First Affiliated Hospital of Tsinghua University) emergency

Objective To investigate the efficacy of lung ultrasound combined with serum C-reactive protein(CRP)and procalcitonin(PCT)in evaluating the efficacy and prognosis of hospital-acquired pneumonia(HAP).Methods A total of 308 HAP patients admitted to the emergency department and intensive care unit(ICU)of First Affiliated Hospital of Tsinghua University from January 2018 to December 2021 were selected and divided into effective group(n=276)and ineffective group(n=32)according to different treatment *** baseline data and the dynamic changes of lung ultrasound score(LUS),CRP and PCT were compared between the two groups before treatment,3 days and 7 days after *** correlation analysis was used to evaluate the correlation between LUS,CRP,PCT and Clinical Pulmonary Infection Score(CPIS)after 3 days and 7 days of *** regression equation was used to analyze the related influencing factors of curative *** operating characteristic(ROC)curve and area under ROC(AUC)were used to analyze the efficacy of LUS,CPR,PCT and the combination of the three in predicting curative ***-Meier(K-M)survival curve was used to analyze the survival rate of patients with high-risk and low-risk LUS,CPR and *** In the effective group,the LUS,CPR and PCT after 3 days and 7 days of treatment were lower than those of the ineffective *** linear correlation analysis showed that LUS,CPR and PCT after 7 days of treatment were positively correlated with CPIS score(P<0.05),among which LUS after 7 days of treatment had the strongest correlation with CPIS(r=0.635).Logistic regression analysis showed that LUS,CPR and PCT were correlated with the efficacy of HAP after 3 days and 7 days of treatment(P<0.05).ROC curve analysis showed that the AUC of LUS,CPR and PCT predicting invalid HAP after 7 days of treatment was higher than that after 3 days of *** AUC of LUS combined with CPR and PCT after 7 days of treatment to predict the ef

关键词： lung ultrasound C-reactive protein Procalcitonin Hospital acquired pneumonia Curative effect Prognosis

Correlation analysis between lung ultrasound scores and pulmonary arterial systolic pressure in patients with acute heart failure admitted to the emergency intensive care unit

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Journal of Intensive Medicine 2024年第1期4卷 125-132页

作者： Ping Xu Basma Nasr Liang Li Wenbin Huang Wei Liu Xuelian Wang Emergency Department Zigong Fourth People’s HospitalZigongChina Institute of Medical Big Data Zigong Academy of Artificial Intelligence and Big Data for Medical ScienceZigongChina Artificial Intelligence Key Laboratory of Sichuan Province ZigongChina Department of Cardiology First Affiliated Hospital of Dalian Medical UniversityDalianChina

Background:No convenient,inexpensive,and non-invasive screening tools exist to identify pulmonary hypertension(PH)-left heart disease(LHD)patients during the early stages of the disease *** study investigated whether different methods of lung ultrasound(LUS)could be used for the initial investigation of ***:This was a single-center prospective observational study which was performed in the Zigong Fourth People’s *** consecutively enrolled patients with heart failure(HF)admitted to the emergency intensive care unit from January 2018 to May *** echocardiography and LUS were performed within 24 h before *** used the Spearman coefficient for correlation analysis between ultrasound scores and pulmonary arterial systolic pressure(PASP).Bland-Altman plots were generated to inspect possible bias,and receiver operating characteristic(ROC)curves were calculated to assess the relationship between ultrasound scores and an intermediate and high echocardiographic probability of ***:Seventy-one patients were enrolled in this study,with an overall median age of 79(interquartile range:71.5–84.0)*** the 71 patients,36(50.7%)cases were male,and 26(36.6%)had an intermediate and high echocardiographic probability of *** four LUS scores in patients with an intermediate and high probability of PH were significantly higher than in patients with a low probability of PH(P<0.05).The correlation coefficient(r)between different LUS scoring methods and PASP was moderate for the 6-zone(r=0.455,P<0.001),8-zone(r=0.385,P=0.001),12-zone(r=0.587,P<0.001),and 28-zone(r=0.535,P<0.001)*** Bland-Altman plots,each of the four LUS scoring methods had a good agreement with PASP(P<0.001).The 8-zone and 12-zone methods showed moderately accurate discriminative values in differentiating patients with an intermediate and high echocardiographic probability of PH(P<0.05).

关键词： Acute heart failure Pulmonary arterial systolic pressure Pulmonary hypertension Left heart disease lung ultrasound

Applications of artificial intelligence in lung ultrasound:Review of deep learning methods for COVID-19 fighting

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Artificial Intelligence in Medical Imaging 2022年第2期3卷 42-54页

作者： Laura De Rosa Serena L'Abbate Claudia Kusmic Francesco Faita Institute of Clinical Physiology Consiglio Nazionale delle RicerchePisa 56124Italy

BACKGROUND The pandemic outbreak of the novel coronavirus disease(COVID-19)has highlighted the need to combine rapid,non-invasive and widely accessible techniques with the least risk of patient’s cross-infection to achieve a successful early detection and surveillance of the *** this regard,the lung ultrasound(LUS)technique has been proved invaluable in both the differential diagnosis and the follow-up of COVID-19 patients,and its potential may be destined to ***,indeed,LUS has been empowered through the development of automated image processing *** To provide a systematic review of the application of artificial intelligence(AI)technology in medical LUS analysis of COVID-19 patients using the preferred reporting items of systematic reviews and meta-analysis(PRISMA)*** A literature search was performed for relevant studies published from March 2020-outbreak of the pandemic-to 30 September *** articles were included in the result synthesis of this *** As part of the review,we presented the main characteristics related to AI techniques,in particular deep learning(DL),adopted in the selected articles.A survey was carried out on the type of architectures used,availability of the source code,network weights and open access datasets,use of data augmentation,use of the transfer learning strategy,type of input data and training/test datasets,and *** Finally,this review highlighted the existing challenges,including the lack of large datasets of reliable COVID-19-based LUS images to test the effectiveness of DL methods and the ethical/regulatory issues associated with the adoption of automated systems in real clinical scenarios.

关键词： lung ultrasound Deep learning Neural network COVID-19 pneumonia Medical imaging

Effect of Focused Cardiac ultrasound in Combination with lung ultrasound on Critically Ill Patients: A Multicenter Observational Study in China

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Chinese Medical Sciences Journal 2021年第4期36卷 257-264页

作者： Hongmin Zhang Lina Zhang Lixia Liu Ying Zhu Wanhong Yin Wei He Xiuling Shang Yangong Chao Liwen Lv Xiaoting Wang Dawei Liu 无 Department of Critical Care Medicine Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Critical Care Medicine Xiangya HospitalCentral South UniversityChangsha 410013China Department of Critical Care Medicine The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011China Department of Critical Care Medicine Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China Department of Critical Care Medicine West China HospitalSichuan UniversityChengdu 610041China Department of Critical Care Medicine Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Critical Care Medicine Fujian Provincial HospitalFuzhou 350001China Department of Critical Care Medicine The First Hospital of Tsinghua UniversityBeijing 100016China Department of Emergency Medicine The People’s Hospital of Guangxi Zhuang Autonomous RegionNanning 530021China Chinese Critical ultrasound Study Group

Objective Focused cardiac ultrasound(FCU)and lung ultrasound(LU)are increasingly being used in critically ill *** study aimed to investigate the effect of FCU in combination with LU on these patients and to determine if the timing of ultrasound examination was associated with treatment *** This is a multicenter cross-sectional observational *** patients admitted to the intensive care unit(ICU)were screened for *** and LU were performed within the first 24 h,and treatment change was proposed by the performer based on the ultrasound results and other clinical *** Among the 992 patients included,502 were examined within 6 h of ICU admission(early phase group),and 490 were examined after 6 h of admission(later phase group).The early phase group and the later phase group had similar proportions of treatment change(48.8%vs.49.0%,χ^(2)=0.003,P=0.956).In the multivariable analysis,admission for respiratory failure was an independent variable associated with treatment change,with an odds ratio(OR)of 2.357[95%confidence interval(CI):1.284-4.326,P=0.006];the timing of examination was not associated with treatment change(OR=0.725,95%CI:0.407-1.291,P=0.275).Conclusions FCU in combination with LU,whether performed during the early phase or later phase,had a significant impact on the treatment of critically ill *** with respiratory failure were more likely to experience treatment change after the ultrasound examination.

关键词： cardiac ultrasound lung ultrasound critically ill point-of-care

Study the Role of lung ultrasound in Assessment of Subclinical Fluid Overload in Maintenance Hemodialysis Patients with Intra-Dialytic Hypertension

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Open Journal of Nephrology 2020年第3期10卷 199-211页

作者： Said S. A. Khamis Yassein S. Yassein Khaled M. A. El Zorkany Waleed A. Mousa Abdellatif S. A. Kora Ahmed Ragheb Department of Medicine Faculty of Medicine Menoufia University Shibin El-Kom Egypt Department of Radiology Faculty of Medicine Menoufia University Shibin El-Kom Egypt Department of Medicine Shibin El-Koom Teaching Hospital Shibin El-Kom Egypt

Objectives: To elucidate the role of lung ultrasound in assessment of subclinical fluid overload in hemodialysis (HD) patients. Background: Volume overload has a significant role in HD patients with difficult blood pressure control. The clinical evaluation of fluid status is challenging and has poor diagnostic accuracy. Extravascular lung water (ELW) represents an important element of body fluid volume. lung ultrasound (LUS) is increasingly used for ELW assessment through the analysis of B-lines artifacts. Methods: Eighty-eight HD patients were followed up prospectively. Patients were divided into 3 groups according to the changes of systolic blood pressure (SBP) during HD sessions. Group (1): patients with intra-dialytic hypertension (n = 12), group (2): patients with intra-dialytic hypotension (n = 28) and group (3): patients with no significant blood pressure variabilities (n = 48). Numbers of B-lines were measured by LUS and IVC diameters were measured pre and post-dialysis. In addition, Endothelin-1 (ET-1) and other routine laboratory tests were done. Results: There were significant increases in the number of B-lines and IVC diameter pre and post-dialysis in group (1) compared to the other two groups. There was significant decrease in post dialysis IVC diameter but not the number of B-lines in group (2) compared with the other two groups. ET-1 level was significantly increased in group 1 compared to the other two groups. There was a statistically significant positive correlation between the pre-dialysis number of B-lines and ET-1. Conclusion: lung ultrasound can be considered a sensitive and specific modality for volume assessment in HD patients especially with intra-dialytic hypertension. We recommend serial LUS as a part of management in this group of patients.

关键词： Intra-Dialytic Hypertension Volume Assessment lung ultrasound B-Lines

Role of lung ultrasound in the Assessment of Hydration Status of Chronic Haemodialysis Patients

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Open Journal of Radiology 2023年第1期13卷 1-16页

作者： Sylviane Fomekong Dongmo Jean-Roger Tapouh Moulion Denis Georges Teuwafeu Samory Guedje Chuangueu François Jérôme Folefack Kaze Boniface Moifo Department of Internal Medicine and Paediatrics Faculty of Health Sciences University of Buea Buea Cameroon Department of Radiology Faculty of Medicine and Pharmaceutical Sciences University of Dschang Dschang Cameroon Department of Internal Medicine and Specialties Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon Department of Radiology and Medical Imaging Faculty of Medicine and Biomedical Sciences University of Yaoundé 1 Yaoundé Cameroon

Background: Fluid overload is frequent in Haemodialysis (HD) and is one of the major factors of cardiovascular morbidity and mortality for chronic HD patients. The main challenge with chronic haemodialysis patients is indeed the maintenance of a normal extracellular volume through dry weight determination. Our study aimed at assessing the role of lung ultrasound in the detection of B-lines for the determination of hydration status in chronic HD patients. Methods: We conducted a cross-sectional study including 31 patients undergoing chronic HD treatment for at least 3 months, in the Yaounde University Teaching Hospital dialysis unit. lung ultrasonography and clinical examinations were performed immediately before dialysis, and 30 minutes after dialysis. Differences between clinical and ultrasound variables before and after dialysis were measured to assess the effects of dialysis. Association between categorical variables was assessed with the Chi-squared test or Fischer test, and Rho’s Spearman coefficient for quantitative variables. Results: There was a reduction in the median of B-lines score after dialysis [12 (7 - 26) versus 8 (5 - 13)], clinical score [2 (1 - 3) versus 0 (-1 - 2)], mean of systolic blood pressure (164.74 ± 26.50 versus 158.48 ± 27.89), frequency of dyspnoea in patients (32.3% versus 6.5%);and raising of the frequency of cramps in patients (0% versus 19.4%) and all statistically significant (p ≤ 0.031). B-lines score before and after dialysis was associated with dyspnoea and raised jugular venous pressure (p Conclusion: lung ultrasound for the detection of B-lines reflects the variation of extracellular volume during dialysis and can even capture pulmonary oedema at a pre-clinical stage. It is then a reliable and sensible method for assessing extravascular lung water and thus hydration status of haemodialysis patients. It could constitute a better alternative for an objective and accurate definition of dry weight, specifically in the African and

关键词： Haemodialysis lung ultrasound B-Lines Hydration Status Clinical Score