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Meta-analysis of the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts in China

引用

Journal of Environmental Sciences 2022年第4期34卷 204-210页

作者： Hao Zhang Hong Li Zhijian Peng Juan Cao Jiemeng Bao Lei Li Xuezhong Wang Yuanyuan Ji Zhuojiong Chen School of Science China University of GeosciencesBeijing 100083China State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Academy of Environmental Planning and Design Co.Ltd.Nanjing UniversityNanjing 210093China College of Earth Sciences Jilin UniversityChangchun 130061China

To investigate the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts of the workers,domestic and foreign published research data on the change of human peripheral blood leukocyte counts under low-level occupational benzene exposure from January 1990 to December 2020 were collected and *** to the literature inclusion and exclusion criteria,18 independent studies from 12 publications were selected for meta-analysis to explore the effect of low-level occupational benzene exposure on human peripheral blood leukocyte *** results showed that the peripheral blood leukocyte counts abnormal rates of low-level occupational benzene exposure group were higher than those of the control group,and the difference was statistically ***-level occupational benzene exposure could result in a relatively higher abnormal rate of peripheral blood leukocyte counts in the exposed population,indicating that low-level occupational benzene exposure at workplaces specified by the current benzene occupational exposure limit in China would affect the peripheral blood leukocyte counts of the workers,thus benzene with concentrations under the limit in the ambient air of workplace could be still harmful to the health of the exposed *** results of this study could provide a scientific basis for future revision of the benzene occupational exposure limit in China,and could also be a reference for the formulation of environmental standard concerning benzene in China in the future.

关键词： Benzene at workplaces low-level occupational exposure Peripheral blood Leukocyte Meta-analysis

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