Meta-analysis of the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts in China

作     者：Hao Zhang Hong Li Zhijian Peng Juan Cao Jiemeng Bao Lei Li Xuezhong Wang Yuanyuan Ji Zhuojiong Chen Hao Zhang;Hong Li;Zhijian Peng;Juan Cao;Jiemeng Bao;Lei Li;Xuezhong Wang;Yuanyuan Ji;Zhuojiong Chen

作者机构：School of ScienceChina University of GeosciencesBeijing 100083China State Key Laboratory of Environmental Criteria and Risk AssessmentChinese Research Academy of Environmental SciencesBeijing 100012China Academy of Environmental Planning and DesignCo.Ltd.Nanjing UniversityNanjing 210093China College of Earth SciencesJilin UniversityChangchun 130061China 

出 版 物：《Journal of Environmental Sciences》 (环境科学学报（英文版）)

年 卷 期：2022年第34卷第4期

页      面：204-210页

核心收录：

学科分类：100405[医学-卫生毒理学] 083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 10[医学] 

基　　金：financially supported by the programs from the Beijing Municipal Science and Technology Commission(No.Z181100005418015) the Special Research Project for the National Environmental Protection Public Welfare Industry of China(No.201009032) the Finance Allocation Project of Ministry of Ecology and Environment of China(No.2110105) 

主　　题：Benzene at workplaces Low-level occupational exposure Peripheral blood Leukocyte Meta-analysis 

摘      要：To investigate the effect of low-level occupational benzene exposure on human peripheral blood leukocyte counts of the workers,domestic and foreign published research data on the change of human peripheral blood leukocyte counts under low-level occupational benzene exposure from January 1990 to December 2020 were collected and *** to the literature inclusion and exclusion criteria,18 independent studies from 12 publications were selected for meta-analysis to explore the effect of low-level occupational benzene exposure on human peripheral blood leukocyte *** results showed that the peripheral blood leukocyte counts abnormal rates of low-level occupational benzene exposure group were higher than those of the control group,and the difference was statistically ***-level occupational benzene exposure could result in a relatively higher abnormal rate of peripheral blood leukocyte counts in the exposed population,indicating that low-level occupational benzene exposure at workplaces specified by the current benzene occupational exposure limit in China would affect the peripheral blood leukocyte counts of the workers,thus benzene with concentrations under the limit in the ambient air of workplace could be still harmful to the health of the exposed *** results of this study could provide a scientific basis for future revision of the benzene occupational exposure limit in China,and could also be a reference for the formulation of environmental standard concerning benzene in China in the future.