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Synovial lipomatosis: A rare cause of knee pain in an adolescent female

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World Journal of Orthopedics 2015年第3期6卷 369-373页

作者： Nicholas Miladore Mary A Childs Vani J Sabesan Department of Orthopaedic Surgery Western Michigan University Homer Stryker M.D.School of Medicine Department of Orthopaedic Surgery Wayne State University School of Medicine

Synovial lipomatosis is a benign proliferative disease of the subsynovial adipose which can lead to a variety of presentations. Cases of synovial lipomatosis in children or adolescents are rare. This case report describes an adolescent patient with a rare bilateral presentation of synovial lipomatosis. She had been treated for years prior to her presentation for juvenile idiopathic arthritis. She presented with chronic bilateral knee pain, swelling, and mechanical symptoms. Bilateral MR imaging demonstrated effusions, hypertrophy of the synovium, and polyp-like projections of tissue with the same signal intensity as fat which is pathognomonic for synovial lipomatosis. Arthroscopic synovectomy and extensive debridement of polyp like fat projections of the right knee was performed. Histopathology was consistent with the synovial lipomatosis diagnosis. Postoperatively, the patient was satisfied with her outcome with improved pain relief and function in her right knee.

关键词： Synovial lipomatosis lipomatosis Knee arthroscopy Lipoma arborescens Arthroscopy Villous lipomatous proliferation of the synovial membrane Knee pain

Corticosteroid-Induced Multifocal and Extensive lipomatosis: A Case Report

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Open Journal of Pathology 2011年第1期1卷 1-3页

作者： Ilham Bouaddi Hanan Rkain Fadoua Allali Nazik Allali Najia Hajjaj-Hassouni 不详

Introduction: Corticosteroid-induced lipomatosis are uncommon situation. We report a case of an extensive lipomatosis in a rheumatoid arthritis patient, who received a long term steroid therapy. Case report: A 49-year-old rheumatoid arthritis woman, who received for two years a mean dose of 15 mg/ day of prednisone equivalent, was admitted to the hospital for a six months history of progressive abdominal distension and dyspnea. Physical exam revealed typical symptoms of Cushing’s syndrome and an important increase of abdominal volume. lipomatosis diagnosis with mesenteric, mediastinal, retroperitoneal and epidural localizations, was rapidly confirmed by sonography and computed tomography (CT) exams. Management was based on corticosteroid reduction as well as use of hygiene and dietary measures. Therapeutic efficacy was noted on a clinical basis within one year. Discussion: lipomatosis occurs as a less known complication of long-term steroid therapy. Its localizations are numerous. Epidural and mediastinal lipomatosis are more frequent than mesenteric or retroperitoneal ones. Most frequently asymptomatic, lipomatosis could sometimes be revealed by false symptoms. Medical treatment including corticosteroid with drawal or reduction and calorie restriction, can lead to clinical improvement. Surgery is reseved in advanced forms with serious complications.

关键词： lipomatosis Mesenteric Retroperitoneal Mediastinal Epidural Corticosteroids

Testicular lipomatosis without Evidence of Cowden’s Disease

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Case Reports in Clinical Medicine 2015年第12期4卷 364-368页

作者： Ahmad Rezayi Azandariani Leili Ebrahimi Sedigheh Saedi Department of Radiology Faculty of Medicine Hamadan University of Medical Sciences Hamadan Iran Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences Tehran Iran

Background: Testicular lipomatosis is a very rare and benign disorder of the testicles. It usually presents as multiple bilateral ill-defined hyper-echoic intra-testicular lesions of different sizes but generally with maximum 4 mm. Testicular lipomatosis is usually reported in association with Cowden’s syndrome. Aim: We aimed to show that there are cases of testicular lipomatosis occurring in the absence of Cowden’s syndrome. Case Presentation: We present a 28-year-old man with testicular pain, who was finally diagnosed as having isolated testicular lipomatosis without other clinical and biochemical abnormalities using magnetic resonance imaging (MRI) technique. Conclusion: We showed that the testicular lipomatosis may occur and be detected without any evidence of Cowden’s disease.

关键词： Testicular lipomatosis Cowden’s Disease Magnetic Resonance Imaging

Renal Replacement lipomatosis—A Rare Benign Condition

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Surgical Science 2018年第9期9卷 306-310页

作者： Vishal Kadeli Rajendra Nerli Shridhar Ghagane Murigendra B. Hiremath Neeraj Dixit Department of Urology JN Medical College KLE Academy of Higher Education & Research (Deemed-to-Be-University) JNMC Campus Belagavi India KLES Kidney Foundation KLES Dr. Prabhakar Kore Hospital & M.R.C. Belagavi India Department of Urology KLES Kidney Foundation KLES Dr. Prabhakar Kore Hospital & M.R.C. Belagavi India Department of Biotechnology and Microbiology Karnatak University Dharwad India

Introduction: Renal replacement lipomatosis is a rare condition that occurs at the end of the spectrum of renal tissue replacement by fat. It is usually unilateral and occurs as a result of severe renal atrophy or destruction usually due to chronic calculus disease, chronic pyelonephritis and renal tuberculosis. The most commonly used diagnostic investigation remains CECT (contrast enhanced computed tomography) scan. Herein we report our series of patients with total renal replacement lipomatosistreated by nephrectomy. Materials & Methods: We retrospectively reviewed our hospital data for cases of RRL, presented and treated during the period Jan. 2006-Dec. 2015. The age, gender, presenting symptoms, clinical and laboratory findings were noted. The indications for surgery, postoperative outcomes and complications were similarly noted and analyzed. Results: Five patients (three females and two males) with a mean age of 48.4 ± 3.2 years presented with symptoms of pain. Computed tomography (CT) in these patients showed the affected kidney to be completely distorted and replaced by ill-defined fatty attenuating lesion. Open nephrectomy was done in all these patients. Histo-pathological report (HPR) revealed features of RRL with renal calculi. Conclusions: Renal replacement lipomatosis is an uncommon entity, and one should have a high index of suspicion when dealing with suspicious lesions similar to xanthogranulomatous pyelonephritis. Specific imaging, operative, and pathological differences may provide clues for the differential diagnosis.

关键词： Renal Replacement lipomatosis Nephrectomy Pathogenesis

Diffuse lipomatosis of Thyroid—Case Report

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Surgical Science 2018年第12期9卷 469-473页

作者： Jahid Ahmed Ratbi El Amine Chad Bouziane Surgical Clinic B University Hospital Ibn Sina Rabat Morocco Department of Pathology University Hospital Ibn Sina Rabat Morocco

Diffuse lipomatosis of thyroid gland is very rare disease, characterized by diffuse proliferation of adipose tissue in the thyroid gland, the pathophysiology of adipose tissue infiltration in the thyroid gland remains unknown. We report a case of a 55-year-old female who presented 6 months ago a dysphonia, ultrasound of the neck revealed the presence diffuse goiter with heterogeneous echogenicity, her thyroid hormone levels were normal, thyroid isotope scanning showed heterogeneous uptake of radioactivity and coexistence of cold and hot nodules. The patient underwent total thyroidectomy. Histological study concluded to the diagnosis of diffuse lipomatosis of thyroid gland.

关键词： Diffuse lipomatosis of Thyroid

MRI character of Pelvic lipomatosis

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MRI character of Pelvic liPomatosis

Gastric pseudolipomatosis, usual or unusual? Re-evaluation of 909 endoscopic gastric biopsies

第十六届全国泌尿外科学术会议

作者： Li xuesong,Wu bing,Gong kan,He zhisong,Zhang qian, Xi zhijun,Li ningchen,Zhou liqun, Wang xiaoying,Guo yinglu 北京大学第一医院泌尿外科北京大学泌尿外科研究所

Introduction and Objective:Pelvic lipomatosis is a rare benign disease of unknown etiology characterized by the Proliferation of infiltrating fatty tissue within the confines of the deeP bony *** the number of rePorte... 详细信息

关键词： MRI Pelvis Bladder obstruction lipomatosis

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World Journal of Gastroenterology 2003年第12期9卷 2846-2848页

作者： Murat Alper Yusuf Akcan Olcay K Belenli Selma Cukur Kamuran A Aksoy Mazlume Suna Departmentof Pathology Medical School of DüzceAbant Izzet Baysal UniversityTurkey Departmentof Gastroenterology Medical School of DüzceAbant Izzet Baysal UniversityTurkey

Microvesicular pneumatosis intestinalis, also called 'pseudolipomatosis' for resembling fatty infiltration, is characterized by the presence of small gas voids in the gastrointestinal wall, especially in mucosa. These voids are not lined with epithelia. There are few reported cases about colon, duodenum and skin. Because there is only one case report about pseudolipomatosis in the stomach, we reevaluated 909 endoscopic biopsies taken from gastric corpus to check the presence of pseudolipomatosis. We determined pseudolipomatosis foci in 3 percent (n=27) of biopsies. In two cases there were pseudolipomatosis foci in endoscopic biopsies having otherwise normal histologic findings, while there were pseudolipomatosis foci in endoscopic biopsies of 25 patients with gastritis. H pylori was found in 85 % of biopsies having pseudolipomatosis foci. In this study, we presented some histopathologic characteristics of pseudolipomatosis seen in gastric mucosa.

关键词： Adult Aged Biopsy Female Gastric Mucosa Humans lipomatosis Male Middle Aged Retrospective Studies Stomach Diseases Vacuoles

Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease

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World Journal of Gastroenterology 2016年第34期22卷 7660-7675页

作者： Roberto Catanzaro Biagio Cuffari Angelo Italia Francesco Marotta Department of Clinical and Experimental Medicine Gastroenterology and Hepatology ServiceInternal Medicine UnitUniversity Hospital Policlinico 'G. Rodolico'University of Catania 95123 Catania Italy ReGenera Research Group for Aging-Intervention 20144 Milano Italy

After the first description of fatty pancreas in 1933,the effects of pancreatic steatosis have been poorly investigated,compared with that of the liver. However,the interest of research is increasing. Fat accumulation,associated with obesity and the metabolic syndrome(Met S),has been defined as "fatty infiltration" or "nonalcoholic fatty pancreas disease"(NAFPD). The term "fatty replacement" describes a distinct phenomenon characterized by death of acinar cells and replacement by adipose tissue. Risk factors for developing NAFPD include obesity,increasing age,male sex,hypertension,dyslipidemia,alcohol and hyperferritinemia. Increasing evidence support the role of pancreatic fat in the development of type 2 diabetes mellitus,Met S,atherosclerosis,severe acute pancreatitis and even pancreatic cancer. Evidence exists that fatty pancreas could be used as the initial indicator of "ectopic fat deposition",which is a key element of nonalcoholic fatty liver disease and/or Met S. Moreover,in patients with fatty pancreas,pancreaticoduodenectomy is associated with an increased risk of intraoperative blood loss and post-operative pancreatic fistula.

关键词： Metabolic syndrome Nonalcoholic fatty liver disease Pancreatic steatosis Pancreatic lipomatosis Nonalcoholic fatty pancreas disease Fatty pancreas Pancreatic fat Pancreatic fatty replacement Pancreatic fatty infiltration Pancreatic cancer

Liposuction for chronic medical diseases and noncosmetic conditions:review of the literature

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Plastic and Aesthetic Research 2015年第1期2卷 1-6页

作者： Hamdy Abuelhassan El-Khatib Department of Plastic and Hand Surgery Alkhor HospitalHamad Medical CorporationDoha 00974Qatar

The purpose of this systematic literature review was to evaluate the safety of liposuction techniques and to identify the cosmetic and noncosmetic application of *** can be used to improve the quality-of-life in patients with disabling medical conditions in addition to its use for cosmetic *** online search of the Cochrane Library,MEDLINE,Embase,and SciELO were ***-seven original articles reported from 1982 to February 2014 were included in this *** articles reported on the use as well as the limitations of liposuction for treatment of noncosmetic and disabling medical *** criteria used for selection of articles were:large sample size and *** case reports were *** was a broad agreement about the applicability and the efficacy of the liposuction for treatment of these chronic medical conditions,such as multiple systemic lipomatosis,dercum’s disease,chronic lymphedema,and axillary *** review confirmed that Liposuction technique has provided significant and stable cure for these chronic medical *** is the most frequent esthetic procedure for adipose tissue reduction and treatment of lipedema *** from esthetic indications,liposuction can also be used to treat chronic medical diseases and noncosmetic conditions.

关键词： Liposuction noncosmetic indications lipomatosis