检索结果-南通市图书馆

Journal of Clinical and Nursing Research 2024年第3期8卷 50-54页

作者： Ruijue Li Zhengzhou University Zhengzhou 450001Henan ProvinceChina

Objective:To explore the effects of local injection of epinephrine and lidocaine on postoperative pain and bleeding in children undergoing ***:Sixty-eight children who underwent a tonsillectomy in our hospital from March 2019 to October 2020 were *** children were randomly divided into two groups of 34 cases *** observation group received local anesthetic injections of lidocaine and the control group received local anesthetic injections of *** postoperative pain,operation time,blood pressure changes,and intraoperative blood loss of the two groups of children were observed and ***:The postoperative pain,operation time,and intraoperative blood loss scores of the children in the observation group were 4.36±0.69,0.36±0.09,and 39.36±1.78 respectively,which were significantly better than those of the children in the control group(P0.05).Conclusion:Local injection of epinephrine and lidocaine effectively relieved postoperative pain and reduced bleeding in children undergoing tonsillectomy as compared to epinephrine alone.

关键词： Epinephrine lidocaine Tonsillectomy Postoperative pain Intraoperative bleeding

lidocaine in fibromyalgia:A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2022年第4期12卷 615-622页

作者： Jozélio Freire de Carvalho Thelma L Skare Health Sciences Institute Federal University of BahiaSalvador 40231-300Brazil Rheumatology Unit Evangélico Mackenzie HospitalCuritiba 80730-420Brazil

BACKGROUND Fibromyalgia(FM)patients are treated with antidepressants,and in most cases,these drugs lose efficacy or present side *** lidocaine(IL)is an anesthetic drug used in some FM *** To systematically review the safety and efficacy of IL in FM *** To systematically search PubMed for articles in English,Spanish,and Japanese with English Abstracts on FM and lidocaine between 1966 and February *** study was registered at *** We found only ten articles published in this field,with a total of 461 *** predominated varying from 95%to 100%in the *** varied from 40.9 to 55 years *** duration varied from 1 mo to 6.4 *** dose varied from 2 to 7.5 mg/kg via intravenous ***-up period varied from 65.7 to 90 *** outcomes,most studies used the visual analogue scale(VAS)for pain;before short-term lidocaine administration,VAS was between 6.1 and 8.1 and after treatment was between 1.7 and 4.5 *** long term lidocaine,VAS varied from 30%to 35.4%after lidocaine *** effects were observed in 0%to 39.6%of cases,they were usually mild or *** This study demonstrates the short-term effectiveness and safety of intravenous lidocaine in FM ***,more studies,including long-term follow-up,are still needed.

关键词： lidocaine Fibromyalgia Pain Intravenous infusions

Effects of propofol combined with lidocaine on hemodynamics, serum adrenocorticotropic hormone, interleukin-6, and cortisol in children

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第24期10卷 8506-8513页

作者： Song Shi Lu Gan Chun-Nv Jin Rong-Fang Liu Department of Anesthesiology Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Anesthesiology Baoding Maternal and Child Health HospitalBaoding 071000Hebei ProvinceChina

BACKGROUND Children are a unique patient *** for pediatric abdominal surgery has long been achieved mainly with intravenous amiodarone and propofol alone or combined with other *** incidence of complications and postoperative adverse reactions is relatively high owing to the imperfect development of various protocols for *** the most appropriate anesthesia program is an important means of reducing adverse *** To explore the clinical value of propofol combined with lidocaine-assisted anesthesia in pediatric *** A total of 120 children who underwent abdominal surgery at our hospital from January 2016 to March 2018 were selected and divided into groups A and B using the random number table method,with 60 patients in each *** B received ketamine for anesthesia,while group A received ketamine,propofol,and *** pre-and postoperative heart rate(HR);mean arterial pressure(MAP);arterial oxygen saturation(SpO_(2));serum adrenocorticotropic hormone(ACTH),interleukin-6(IL-6),and cortisol(Cor)levels;restlessness score during the recovery period[Paediatric Anesthesia Emergence Delirium Scale(PAED)];and adverse reactions were compared between the two *** The HR,MAP,and SpO_(2) Level at five minutes before initiating anesthesia were compared between groups A and B,and the difference was not statistically significant(P>0.05).At 10 and 20 minutes after anesthesia initiation,the HR and MAP were lower in group A compared with group B(P0.05);however,the postoperative serum ACTH,IL-6,and Cor levels in group A were lower compared with group B(P<0.05).Furthermore,the visual analog scale scores of group A at 2 h and 8 h postoperative were lower than those in group B,and the differences were statistically significant(P<0.05).The mean PAED score in group A was lower than t

关键词： Ketamine Propofol lidocaine Anesthesia Children

Efficacy of lidocaine wet compress combined with red-light irradiation for chronic wounds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第30期11卷 7277-7283页

作者： Man-Zhen Bao Lian-Bang Zhou Ling Zhao Hui Zhang Yuan Li Li Yang An-Ting Tai Department of Nursing The Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina Department of General Surgery The Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina Department of General Surgery Huaibei People’s Hospital of Anhui ProvinceHuaibei 235000Anhui ProvinceChina Department of Outpatient The Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina

BACKGROUND Chronic wounds that fail to progress through normal phases of healing present a significant healthcare burden owing to prolonged treatment and associated *** wound care typically involves regular dressing changes,which can be *** approaches have explored the use of lidocaine to manage pain and red-light irradiation(RLI),known for its anti-inflammatory and cell proliferation effects,to potentially enhance wound *** To investigate the therapeutic efficacy of lidocaine wet compression(LWC)combined with RLI for chronic *** We enrolled 150 patients with chronic wounds from the Wound and Ostomy Outpatient Clinic of the Second Hospital of Anhui Medical University from April to September *** wounds were treated with dressing *** patients were randomly assigned to the control and experimental groups using a random number table and given the same first dressing change(2%LWC for 5 min and routine dressing change).From the second dressing change,in addition to 2%LWC for 5 min and routine dressing change,the experimental group received RLI,whereas the control group continued to receive the same LWC and dressing *** first and second dressing changes were performed on days 1 and 2,*** third dressing change was performed 3 d after the second *** frequency of subsequent dressing changes was determined based on wound exudation and *** during the first three dressing changes was evaluated in both *** average number of dressing changes within 28 d and the degree of wound healing on day 28 were also *** During the initial dressing change,no noticeable differences were observed in the pain levels experienced by the two groups,indicating similar pain ***,during the second and third dressing changes,the experimental group reported significantly less pain than the control ***,over 28 d,the experimental group required fewer dressing changes than

关键词： Chronic wound lidocaine Red light Pain Quality of Life Wound exudation

Effect of esmolol and lidocaine on agitation in awake phase of anesthesia among children:a double-blind,randomized clinical study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2019年第7期132卷 757-764页

作者： Jae Young Ji Jin Soo Park Ji Eun Kim Da Hyung Kim Jin Hun Chung Hea Rim Chun Ho Soon Jung Sie Hyeon Yoo Department of Anesthesiology and Pain Medicine Soonchunhyang University Hospital Cheonan31Soonchunhyang 6-gilDongnam-guCheonan-siChungcheongnam-do 330-721Korea

Background:Sevoflurane is widely used to anesthetize children because of its rapid action with minimal irritation of the ***,there is a high risk of agitation after emergence from *** surgery,in particular,can trigger agitation because patients have their eyes covered in the postoperative *** aim of this study was to determine whether or not esmolol and lidocaine could decrease emergence agitation in ***:Eighty-four patients aged 3 to 9 years undergoing strabismus surgery were randomly assigned to a control group(saline only),a group that received intravenous lidocaine 1.5 mg/kg,and a group that received intravenous esmolol 0.5 mg/kg and lidocaine 1.5 mg/*** was measured using the objective pain score,Cole 5-point score,and Richmond Agitation Sedation Scale score at the end of surgery,on arrival in the recovery room,and 10 and 30 min after ***:The group that received the combination of esmolol and lidocaine showed lower OPS and RASS scores than the other two groups when patients awoke from anesthesia(OPS=0(0-4),RASS=-4[(-5)-1])and were transferred to the recovery room(OPS=0(0-8),RASS=-1[(-5)-3])(P0.05).Conclusions:When pediatric strabismus surgery is accompanied by sevoflurane anesthesia,an intravenous injection of esmolol and lidocaine could alleviate agitation until arrival in the recovery room.

关键词： Agitation Esmolol lidocaine Sevoflurane

CuO-nanoparticles modified carbon paste electrode for square wave voltammetric determination of lidocaine: Comparing classical and Box–Behnken optimization methodologies

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2016年第6期27卷 837-842页

作者： Nadereh Rahbar Zahra Ramezani Jamalaldin Ghanavati Nanotechnology Research Center Faculty of Pharmacy Ahvaz Jundishapur University of Medical Sciences Medicinal Chemistry Department Ahvaz Jundishapur University of Medical Sciences

In this research, copper oxide nanoparticles modified carbon paste electrode was developed for the voltammetric determination of lidocaine. The square wave voltammogram of lidocaine solution showed a well-defined peak between ＋0.5 and ＋1.5 V. Instrumental and chemical parameters influencing voltammetric response were optimized by both one at a time and Box–Behnken model of response surface methodology. The results revealed that there was no significant difference between two methods of optimization. The linear range was 1–2500 μmol L^-1（Ip= 0.11 C（LH）＋ 17.38, R^2= 0.999）. The LOD and LOQ based on three and ten times of the signal to noise（S/N） were 0.39 and 1.3 μmol L^-1（n = 10）,respectively. The precision of the method was assessed for 10 replicate square wave voltammetry（SWV）determinations each of 0.05, 0.5 and 1 μmol L^-1 of lidocaine showing relative standard deviations 4.1%,3.7% and 2.1%, respectively. The reliability of the proposed method was established by application of the method for the determination of lidocaine in two pharmaceutical preparations, namely injection and gel.

关键词： Square wave voltammetry CuO nanoparticles lidocaine Modified carbon paste electrode

Inhibitory effects of lidocaine on cerebral vasospasm in a rabbit model of subarachnoid hemorrhage

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第21期5卷 1657-1662页

作者： Xianqing Shi Baning Ye Yuandong Hu Yuhui Wang Jianquan Li Daqing Liao Jin Liu Intensive Care Unit Guizhou Province People's Hospital Guiyang 550002 Guizhou Province China Laboratory of Anaesthesia and Critical Medicine West China Hospital Sichuan University Chengdu 610041 Sichuan Province China

Following subarachnoid hemorrhage, vasoconstrictor substances, cellular apoptosis, blood coagulation, and vascular cell proliferation affect the onset of cerebral vasospasm. Previous studies from our laboratory have revealed that injection of lidocaine （2 mg） into the cisterna magna reduces cerebral vasospasm and nerve functional impairment in an animal model of subarachnoid hemorrhage. The present study determined the optimal lidocaine dose for vasospasm and brain injury by injecting different doses of lidocaine into the cisterna magna in a rabbit model of subarachnoid hemorrhage. Results showed that endothelin, tumor necrosis factor-a, and interleukin-6 levels significantly increased in plasma, and calcitonin gene-related peptide levels significantly decreased in plasma （P 〈 0.05）. The number of neurons was decreased, the number of cells expressing c-Fos increased in the hippocampus, and cross-sections and diameters of basilar arteries were reduced （P 〈 0.05）. These changes significantly improved following injection of lidocaine （1,2, 4, and 6 mg） into the cisterna magna. A dose of 6 mg lidocaine into the cisterna magna resulted in optimal effects on cerebral vasospasm and brain injury following subarachnoid hemorrhage.

关键词： lidocaine subarachnoid hemorrhage cerebral vasospasm neuroprotection rabbit

Efficacy of amiodarone and lidocaine for preventing ventricular fibrillation after aortic cross-clamp release in open heart surgery:a meta-analysis of randomized controlled trials

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第12期18卷 1113-1122页

作者： Yong ZHENG Qiang GU Hong-wu CHEN Huai-ming PENG Dong-yu JIA Yu ZHOU Mei-xiang XIANG Department of Cardiology the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China Cardiovascular Key Lab of Zhejiang Province the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China Department of Anesthesiology the First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China Cardiology Division the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Respiratory Tinhu People's HospitalYancheng 224001China Department of Biology Georgia Southern UniversityStatesboro 30460USA

Objective： The relative preventative efficacy of amiodarone and lidocaine for ventricular fibrillation（VF） after release of an aortic cross-clamp（ACC） during open heart surgery has not been determined. This meta-analysis was designed to systematically evaluate the influence of amiodarone, lidocaine, or placebo on the incidence of VF after ACC. Methods： Prospective randomized controlled trials（RCTs） that compared the VF-preventative effects of amiodarone with lidocaine, or amiodarone or lidocaine with placebo were included. Pub Med, EMBASE, and the Cochrane Library were searched for relevant RCTs. Fixed or randomized effect models were applied according to the heterogeneity of the data from the selected studies. Results： We included eight RCTs in the analysis. Pooled results suggested that the preventative effects of amiodarone and lidocaine were comparable（relative risk（RR）=1.12, 95% confidence interval（CI）： 0.70 to 1.80, P=0.63）, but both were superior to the placebo（amiodarone, RR=0.71, 95% CI： 0.51 to 1.00, P=0.05; lidocaine, RR=0.63, 95% CI： 0.46 to 0.88, P=0.006）. The percentage of patients requiring electric defibrillation counter shocks（DCSs） did not differ significantly among patients administered amiodarone（RR=0.21, 95% CI： 0.04 to 1.19, P=0.08）, lidocaine（RR=2.44, 95% CI： 0.13 to 44.02, P=0.55）, or the placebo（RR=0.56, 95% CI： 0.25 to 1.25, P=0.16）. Conclusions： Amiodarone and lidocaine are comparably effective in preventing VF after ACC, but the percentage of patients who subsequently require DCSs does not differ among those administered amiodarone, lidocaine, or placebo.

关键词： Amiodarone lidocaine Ventricular fibrillation Open heart surgery

Posterior lingual lidocaine: A novel method to improve tolerance in upper gastrointestinal endoscopy

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第47期17卷 5191-5196页

作者： Assaad M Soweid Shadi R Yaghi Faek R Jamali Abdallah A Kobeissy Michella E Mallat Rola Hussein Chakib M Ayoub Department of Internal Medicine American University of Beirut Medical Center 1107 2020 Beirut Lebanon Department of Surgery American University of Beirut Medical Center 1107 2020 Beirut Lebanon Department of Anesthesiology American University of Beirut Medical Center 1107 2020 Beirut Lebanon

AIM: To evaluate the effect of posterior lingual lidocaine swab on patient tolerance to esophagogastro-duodenoscopy, the ease of performance of the procedure, and to determine if such use will reduce the need for intravenous sedation. METHODS: Eighty patients undergoing diagnostic esophagogastroduodenoscopy in a tertiary care medical center were randomized to either lidocaine swab or spray. Intravenous meperidine and midazolam were given as needed during the procedure. RESULTS: Patients in the lidocaine swab group (SWG) tolerated the procedure better than those in the spray group (SPG) with a median tolerability score of 2 (1, 4) compared to 4 (2, 5) (P lidocaine swab. CONCLUSION: The use of a posterior lingual lidocaine swab in esophagogastroduodenoscopy improves patient comfort and tolerance and endoscopist satisfaction and decreases the need for intravenous sedation.

关键词： Esophagogastroduodenoscopy Upper gas-trointestinal endoscopy Local anesthesia lidocaine Sedation

Comparative efficacy of ketamine,lidocaine,acetaminophen,and dexmedetomidine combined with morphine patient-controlled analgesia in treating opium-addicted patients undergoing tibia fracture surgery:A randomized clinical trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Acute Disease 2022年第5期11卷 181-187页

作者： Hesameddin Modir Esmail Moshiri Mehran Azami Maryam Joshaghani Zad Amir Almasi Hashiani Anesthesiology Department Arak University of Medical Sciences Arak Iran Department of Orthopedic Surgery Arak University of Medical SciencesArakIran Student Research Committee Arak University of Medical Sciences ArakIran Department of Epidemiology School of HealthArak University of Medical SciencesArakIran

Objective:To compare the effect of ketamine,lidocaine,acetaminophen,and dexmedetomidine combined with morphine patient-controlled analgesia for opium addicts after tibial fracture ***:This double-blind clinical trial included opium-addicted patients undergoing tibia fracture *** were recruited and randomized to four different groups including the ketamine group,the lidocaine group,the acetaminophen group,and the dexmedetomidine *** hemodynamic parameters such as heart rate(HR),mean arterial pressure,and arterial SaO2,alongside visual analog scale pain scores,sedation assessed by Ramsay score,nausea and vomiting,and opioid use were recorded and compared among the four ***:This study included 140 patients,aged 37(32,41)years,with 92 males and 48 females,and each group had 35 ***-sedated subjects had the lowest blood pressure from 1 to 24 h after surgery,decreased HR at 12 and 24 h after surgery,and more satisfactory sedation(P0.05).Conclusions:Dexmedetomidine has a better sedation effect compared to ketamine,lidocaine,and acetaminophen for pain control,but the final choice hinges on the patients’physical condition and the anesthesiologist's *** registration:It is registered in Iranian Registry Clinical Trial by code IRCT20141209020258N146.

关键词： Acetaminophen Dexmedetomidine Ketamine lidocaine Morphine Opium-addicted patients Tibia fracture surgery Patient-controlled analgesia pump Postoperative pain