Effect of esmolol and lidocaine on agitation in awake phase of anesthesia among children:a double-blind,randomized clinical study
Effect of esmolol and lidocaine on agitation in awake phase of anesthesia among children: a double-blind, randomized clinical study作者机构：Department of Anesthesiology and Pain MedicineSoonchunhyang University Hospital Cheonan31Soonchunhyang 6-gilDongnam-guCheonan-siChungcheongnam-do 330-721Korea
出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)
年 卷 期：2019年第132卷第7期
页 面：757-764页
核心收录：
学科分类：10[医学]
基 金：supported by the Soonchunhyang University Research Fund
主 题：Agitation Esmolol Lidocaine Sevoflurane
摘 要：Background:Sevoflurane is widely used to anesthetize children because of its rapid action with minimal irritation of the ***,there is a high risk of agitation after emergence from *** surgery,in particular,can trigger agitation because patients have their eyes covered in the postoperative *** aim of this study was to determine whether or not esmolol and lidocaine could decrease emergence agitation in ***:Eighty-four patients aged 3 to 9 years undergoing strabismus surgery were randomly assigned to a control group(saline only),a group that received intravenous lidocaine 1.5 mg/kg,and a group that received intravenous esmolol 0.5 mg/kg and lidocaine 1.5 mg/*** was measured using the objective pain score,Cole 5-point score,and Richmond Agitation Sedation Scale score at the end of surgery,on arrival in the recovery room,and 10 and 30 min after ***:The group that received the combination of esmolol and lidocaine showed lower OPS and RASS scores than the other two groups when patients awoke from anesthesia(OPS=0(0-4),RASS=-4[(-5)-1])and were transferred to the recovery room(OPS=0(0-8),RASS=-1[(-5)-3])(P0.05).Conclusions:When pediatric strabismus surgery is accompanied by sevoflurane anesthesia,an intravenous injection of esmolol and lidocaine could alleviate agitation until arrival in the recovery room.
维普期刊数据库
同方期刊数据库