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Open Journal of Obstetrics and Gynecology 2024年第2期14卷 240-249页

作者： Laura Rankin Matthew Romagano Shauna Williams Joseph Apuzzio Department of Obstetrics Gynecology and Reproductive Health Rutgers New Jersey Medical School Newark USA Lehigh Valley Health Network Division of Maternal Fetal Medicine Allentown USA

Objective: The objective of this study was to determine if early rupture of membranes (ROM) in women undergoing induction of labor (IOL) at term is associated with an increased rate of clinical chorioamnionitis. Study Design: A retrospective cohort study was performed on women undergoing IOL. Early ROM was defined as ROM at a modified Bishop score less than 5, cervical dilation less than 4 cm, or cervical effacement less than 80%. The rate of clinical chorioamnionitis was compared between women with early and late ROM. Results: The rate of clinical chorioamnionitis was 8.6% (24/279). ROM at an effacement of less than 80% was associated with a rate of clinical chorioamnionitis of 15.4% (12/78) compared to 6.0% (12/201) at an effacement of equal to or greater than 80%, p = 0.017. The rate of cesarean delivery was higher for patients with early ROM by any definition: 32% compared to 17.5% by modified Bishop score (p = 0.031), 32.4% versus 18.2% by cervical dilation (p = 0.049), and 33.3% versus 14.9% by cervical effacement (p = 0.001). Conclusions: In patients undergoing IOL, early ROM may be associated with an increased rate of clinical chorioamnionitis when performed at a cervical effacement of less than 80% and an increased rate of cesarean delivery.

关键词： Amniotomy Cesarean Delivery Chorioamnionitis induction of labor Intraamniotic Infection Perinatal Infection Rupture of Membranes Term Pregnancy

Impact of Early versus Late Amniotomy on induction of labor in Nulliparous Women after Vaginally Administered Misoprostol: A Randomized Clinical Trial

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Reproductive and Developmental Medicine 2021年第3期5卷 148-153页

作者： Mohamed Elsibai Anter Ayman Abd Elkader Shabbana Alaa Eldin Fatahlla Elhalaby Hager Abd Elshafy Abd Elfattah Youssif Nabih Ibrahim Elkhouly Department of Obstetrics and Gynecology Faculty of MedicineMenoufia UniversityMenoufiaEgypt

Objective::To investigate the effect of early versus late amniotomy after induction of labor(IOL)with vaginally administered ***::This randomized clinical trial was conducted at the Department of Obstetrics and Gynecology,Menoufia University,from May 2019 to March 2020,and included 120 nulliparous women at term(≥37 weeks’gestation)undergoing ***-generated randomization was used to randomize the participants into either the early amniotomy group(3 cm cervical dilatation;n=60)or the late amniotomy group(7 cm cervical dilatation;n=60).All participants received misoprostol(25μg)vaginally to induce *** primary outcome was the induction-to-delivery interval,defined as the time from the initiation of IOL to the time of ***::Women in the early amniotomy group had a shorter duration of labor(12.60±5.36 h)than those in the late amniotomy group(16.67±7.26 h).The mean time from rupture of the fetal membrane to delivery was significantly shorter in the late(2.51±0.36 h)than in the early amniotomy group(3.1±0.89 h).There was no statistically significant difference between the groups in terms of maternal complications(fever,nausea,vomiting,and uterine hyperstimulation)or neonatal complications(meconium-stained liquor,APGAR scorelabor and decreased use of *** was no significant difference between the early and late amniotomy groups in terms of the rate of cesarean section or maternal and neonatal complications.

关键词： Amniotomy induction of labor Neonatal Outcomes Vaginal Misoprostol

Transvaginal Sonographic Assessment of the Cervix for Prediction of Successful induction of labor in Nulliparous Women

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Open Journal of Obstetrics and Gynecology 2020年第7期10卷 892-901页

作者： Mohamed Abdelhameed Abdelhafeez Alaa Eldin Elguindy Mohamed Abu-El-Fetoh Mohamed Hamed Maii Nawara Department of Obstetrics and Gynecology Ain Shams University Cairo Egypt

Background: induction of labor is commonly performed in obstetric practice. Many methods have been suggested as good predictors of the outcome of labor induction, yet none of them is satisfactory enough. Our study aim... 详细信息

Background: Induction of labor is commonly performed in obstetric practice. Many methods have been suggested as good predictors of the outcome of labor induction, yet none of them is satisfactory enough. Our study aims to assess cervical length and uterocervical angle measured by transvaginal ultrasound as predictors of successful induction of labor. Methods: Prospective cohort study conducted in Ain Shams University Maternity hospital over 150 nulliparous women undergoing induction of labor, in the period between May 2018 and August 2019. Transvaginal sonographic measurement of cervical length and uterocervical angle was done before induction of labor by prostaglandins. The patients were followed up till delivery and the outcome was recorded. Results: The best cut-off value of cervical length for prediction of success of labor induction was 32.3 mm with 60% sensitivity and 56% specificity and the best cut-off value of uterocervical angle was 110.2 degrees with 87% sensitivity and 93% specificity. The cervical length showed a significant negative correlation while the uterocervical angle showed a significant positive correlation with the success of labor induction. Conclusion: Cervical length and uterocervical angle are good predictors of successful labor induction.

关键词： induction of labor Cervical Length Uterocervical Angle

Effectiveness of Dinoprostone and Cook's Balloon for labor induction in Primipara Women at Term

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Current Medical Science 2020年第5期40卷 951-959页

作者： Hui DU Na ZHANG Chan-yun XIAO Guo-qiang SUN Yun ZHAO Department of Obstetrics Maternity and Child Health Hospital of Hubei ProvinceTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430070China

labor induction is commonly used for achieving successful vaginal *** study aimed to compare the effectiveness of dinoprostone and Cook's balloon as labor-inducing agents in primipara women at term.A retrospective cohort study among primipara women was conducted in Hubei Maternity and Child Health *** clinical characteristics were *** main outcomes were vaginal delivery rate,cesarean section rate and forceps delivery *** and perinatal outcomes were also *** and multivariate analyses were further performed to evaluate the predictors for vaginal delivery within 24 h.A total of 845 eligible primipara women undergoing labor induction were *** them,141 women were induced with dinoprostone(dinoprostone group,DG),and 704 with Cook's balloon(Cook's balloon group,CG).Groups were homogeneous except more women with premature rupture of membranes in DG,with gestational hypertension in CG(Plabor than CG(Plabor and achieve vaginal birth in the sample of primipara women at term.

关键词： Cook's balloon dinoprostone induction of labor vaginal delivery independent predictors

Comparison of the effectiveness and pregnancy outcomes of labor induction with dinoprostone or single-balloon catheter in term nulliparous women with borderline oligohydramnios

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Chinese Medical Journal 2022年第6期135卷 681-690页

作者： Yongqing Zhang Luping Chen Guohui Yan Menglin Zhou Zhengyun Chen Zhaoxia Liang Danqing Chen Department of Obstetrics Women's HospitalSchool of MedicineZhejiang UniversityHangzhouZhejiang 310006China

Backgrounds:At present,there is no consensus on the induction methods in term pregnancy with borderline *** study aimed to compare the effectiveness and pregnancy outcomes of labor induction with dinoprostone or single-balloon catheter(SBC)in term nulliparous women with borderline ***:We conducted a retrospective cohort study from January 2016 to November *** the study period,a total of 244 cases were *** these,103 cases were selected for induction using dinoprostone and 141 cases were selected for induction with *** pregnancy outcomes between the two groups were *** outcomes were successful vaginal delivery *** outcomes were maternal and neonatal adverse *** logistic regression was used to assess the risk factors for vaginal delivery failure in the two ***:The successful vaginal delivery rates were similar between the dinoprostone group and the SBC group(64.1%[66/103]vs.59.6%,[84/141]P=0.475),even after adjustment for potential confounding factors(adjusted odds ratio[aOR]:1.07,95%confidence interval[CI]:0.57-2.00,P=0.835).The incidence of intra-amniotic infection was lower in the dinoprostone group than in the SBC group(1.9%[2/103]vs.7.8%[11/141],Pinduction with dinoprostone(aOR:6.71,95%CI:1.96-22.95).There were three factors related to vaginal delivery failure after induction with SBC,namely gestational age(aOR:1.51,95%CI:1.07-2.14),body mass index(BMI)>30 kg/m^(2)(aOR:2.98,95%CI:1.10-8.02),and fetal weight>3500 g(aOR:2.49,95%CI:1.12-5.50).Conclusions:Term nulliparous women with borderline oligohydramnios have similar successful vaginal delivery rates after induction with dinoprostone or SBC,with

关键词： Borderline oligohydramnios induction of labor Single-balloon catheter Dinoprostone Nuchal cord

The Efficacy and Safety of Dinoprostone Vaginal Insert for labor induction Following Optimization of Standard Operating Procedure: A Retrospective Study in China

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Journal of Clinical and Nursing Research 2023年第4期7卷 110-119页

作者： Ping Jin Bao-Min Yin Department of Obstetrics Zhuhai Center for Maternal and Child Health CareZhuhai 519000China

Background:The study aimed to assess the efficacy and safety of dinoprostone vaginal insert in labor induction following optimization of standard operating procedure(SOP)and to discover independent predictors of vaginal ***:This study comprised 551 pregnant women who required cervical ripening with dinoprostone before induction of *** univariate and multivariate analyses,independent predictors of vaginal delivery were ***:443 of the 551 women(80.4%)gave birth *** delivery was predicted by maternal age(24-30 vs.induction of labor.

关键词： Dinoprostone vaginal insert induction of labor Standard operating procedure Vaginal delivery

Birthing ball on promoting cervical ripening and its influence on the labor process and the neonatal blood gas index

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World Journal of Clinical Cases 2021年第36期9卷 11330-11337页

作者： Hai-Chuan Shen Huan Wang Bo Sun Lan-Zhi Jiang Qian Meng Obstetrical Department Lianyungang Maternal and Child Health HospitalLianyungang 222000Jiangsu ProvinceChina

BACKGROUND Term pregnancy-induced labor refers to the use of artificial methods to induce uterine contractions and terminate pregnancy after 37 *** is a common method to prevent overdue pregnancy and to deal with high-risk *** addition,it can alleviate maternal complications and cause the fetus to leave the adverse intrauterine environment early,which is beneficial to the outcome of *** To explore the effect of a birthing ball on labor by inducing cervical ripening and its influence on labor and the neonatal blood gas *** Twenty-two women who were scheduled to undergo labor induction and delivery in the obstetrics department of our hospital were randomly divided into two groups:the delivery ball group(childbirth ball combined with COOK balloon induction)and the conventional group(COOK balloon induction alone).The cervical Bishop score before and after intervention,duration of labor at each stage,mode of delivery,neonatal umbilical venous blood pH,oxygen partial pressure(PO_(2)),carbon dioxide partial pressure(PCO_(2)),and the 1-min Apgar score were *** After the intervention,the cervical Bishop score of the delivery ball group(7.84±1.52)was significantly higher than that of the conventional group(7.32±1.29)(Plabor(510.9±98.7 min),the second stage of labor(43.0±8.5 min),and the total duration of labor(560.0±120.9 min)in the delivery ball group were lower than those in the routine group,with a first stage of labor of 602.1±133.2 min,a second stage of labor of 48.4±9.1 min,and a total duration of labor of 656.8±148.5 min(Plabor between the two groups(P>0.05).There was no significant difference in the pH,PO_(2),and PCO_(2) values of newborns between the delivery ball gro

关键词： Childbirth ball induction of labor Promotion of cervical ripening labor Blood gas index COOK balloon

Efficacy and Safety of Misoprostol Vaginal Insert to Induce labor beyond 40 + 0 Weeks of Gestation

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Open Journal of Obstetrics and Gynecology 2021年第10期11卷 1333-1341页

作者： Catharina Krause Christian Rudlowski Melanie Erices-Leclercq David Tenckhoff Sabine Lubig Department of Obstetrics and Gynecology Lutheran Hospital Begisch Gladbach Germany University Hospital Bonn Bonn Germany

Objective: Misoprostol vaginal insert (MVI) is proven to induce labor by a continuously release of PGE1. Previous reports showed that MVI reduced induction to delivery time as well as active labor time but it also increased uterine tachysystole. Here we attempted to clarify whether MVI is safe and efficient for women with pregnancies >40 weeks in a single institute. Methods: This study was performed in Lutheran Hospital Bergisch Gladbach, Germany 2014-2019. A total of 304 women between 40 + 0 to 42 + 0 weeks underwent labor induction with MVI. Outcomes were: 1) maternal: time from insertion to delivery, interventions, mode of delivery, and uterine tachysystole, 2) neo-natal: cord blood pH, APGAR scores, and admission to a neonatal clinic. This study ended unexpectedly due to the withdrawal of MVI (MisodelTM) in September 2019. Results: 75.7% (n = 230) of women gave birth within 24 hours after MVI placement. 72.2% (n = 140) nulliparous women and 81.8% (n = 90) parous women delivered within 24 hours. In two cases emergency CS was required. 67.8% (n = 206) of women delivered vaginal. 2.3% (n = 7) of cord pH levels were be

关键词： Misoprostol Vaginal Insert induction of labor Caesarean Section Vaginal Delivery

A Qualitative Study on the Psychological Experience of Pregnant Women with Abnormal Induced Abortion of Fetuses under 20 Weeks of Pregnancy

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Open Journal of Obstetrics and Gynecology 2023年第7期13卷 1133-1141页

作者： Chunrong Pu Department of Obstetrics Deyang People’s Hospital Deyang China

Objective: This paper aims to understand the psychological experience and needs of pregnant women who need induction of labor due to fetal abnormalities at less than 20 weeks of gestation through in-depth interviews. Methods: Using the phenomenological research method in qualitative research, 12 pregnant women with fetal abnormalities less than 20 weeks of gestation in the obstetrics department of a hospital from January to April 2023 were selected as the research objects for semi-structured in-depth interviews. After information was collected to saturation, Colaizzi content analysis method was used to sort out, analyze and refine the data. Results: Through the interview results, three themes were refined from the transcript. Those are: 1) the support and assistance needed during the induction of labor;2) inner feelings after labor induction;3) The vision of future life. Conclusion: Abnormal fetal development at induction of labor, pregnant women have to experience many physical and mental suffering, and need to get the care of family, relatives, friends, medical staff and society. Medical staff can help them seek multi-directional support, provide professional knowledge, and help them with self-management.

关键词： <20 Weeks of Gestation Fetal Abnormalities induction of labor Psychological Experience Qualitative Research